PPA2 Protein

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PPA2

Official Full Name	pyrophosphatase (inorganic) 2
Background	The protein encoded by this gene is localized to the mitochondrion, is highly similar to members of the inorganic pyrophosphatase (PPase) family, and contains the signature sequence essential for the catalytic activity of PPase. PPases catalyze the hydrolysis of pyrophosphate to inorganic phosphate, which is important for the phosphate metabolism of cells. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Synonyms	PPA2; pyrophosphatase (inorganic) 2; inorganic pyrophosphatase 2, mitochondrial; FLJ20459; HSPC124; PPase2; Pyrophosphatase SID6 306; PPase 2; OTTHUMP00000158985; OTTHUMP00000158986; OTTHUMP00000218513; OTTHUMP00000218514; pyrophosphatase SID6-306; pyrophosphate phospho-hydrolase 2; SID6-306

Species :
Human
Mouse
Yeast
Zebrafish

Source :
E.coli
HEK293
HEK293T
Mammalian Cell

Tag :
GST
His
Myc/DDK
N/A

Species	Cat.#	Product name	Source (Host)	Tag
Human	PPA2-242H	Recombinant Human PPA2 Protein, His-tagged	E.coli	His
Human	PPA2-2994HCL	Recombinant Human PPA2 293 Cell Lysate	HEK293	N/A
Mouse	PPA2-13153M	Recombinant Mouse PPA2 Protein	Mammalian Cell	His
Mouse	Ppa2-5028M	Recombinant Mouse Ppa2 Protein, Myc/DDK-tagged	HEK293T	Myc/DDK
Zebrafish	PPA2-11689Z	Recombinant Zebrafish PPA2	Mammalian Cell	His
Yeast	ppa2-1868Y	Recombinant Yeast ppa2, GST-tagged	E.coli	GST

Involved Pathway Protein Function Interacting Protein PPA2 Related Articles

PPA2 involved in several pathways and played different roles in them. We selected most pathways PPA2 participated on our site, such as Oxidative phosphorylation, which may be useful for your reference. Also, other proteins which involved in the same pathway with PPA2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Oxidative phosphorylation	NDUFS5; ATP4B; NDUFV3; ATP5G1; NDUFS1; ATP6V0A1B; ATP6V1BA; ATP6V1C1; UQCRC2B; NDUFS8

PPA2 has several biochemical functions, for example, inorganic diphosphatase activity, magnesium ion binding, protein serine/threonine phosphatase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PPA2 itself. We selected most functions PPA2 had, and list some proteins which have the same functions with PPA2. You can find most of the proteins on our site.

Function	Related Protein
inorganic diphosphatase activity	PPA1B; LHPP; PPA2; PPA1; PPA1A; PRUNE
magnesium ion binding	PGM1; ENO1A; COMTA; PINK1; ENO1; GSS; STK38L; NUDT3; PPM1AA; PPM1AB
protein serine/threonine phosphatase activity	DUSP23B; PPM1H; CDC14AB; PHLPP2; PDP2; PPEF2; PPP2R5D; PPM1DA; TIMM50; CDC14C

PPA2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PPA2 here. Most of them are supplied by our site. Hope this information will be useful for your research of PPA2.

HTT; 15-deoxy-delta(12,14; ZWINT; MYC; COMT; SIRT4

Gomez-Garcia, MR; Serrano, A; et al. Expression studies of two paralogous ppa genes encoding distinct Family I pyrophosphatases in marine unicellular cyanobacteria reveal inactivation of the typical cyanobacterial gene. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 295:890-897(2002).

Rojas-Beltran, JA; Dubois, F; et al. Identification of cystosolic Mg2+-dependent soluble inorganic pyrophosphatases in potato and phylogenetic analysis. PLANT MOLECULAR BIOLOGY 39:449-461(1999).

PPA2

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PPA2

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