|Official Full Name||pyrophosphatase (inorganic) 2|
|Background||The protein encoded by this gene is localized to the mitochondrion, is highly similar to members of the inorganic pyrophosphatase (PPase) family, and contains the signature sequence essential for the catalytic activity of PPase. PPases catalyze the hydrolysis of pyrophosphate to inorganic phosphate, which is important for the phosphate metabolism of cells. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.|
|Synonyms||PPA2; pyrophosphatase (inorganic) 2; inorganic pyrophosphatase 2, mitochondrial; FLJ20459; HSPC124; PPase2; Pyrophosphatase SID6 306; PPase 2; OTTHUMP00000158985; OTTHUMP00000158986; OTTHUMP00000218513; OTTHUMP00000218514; pyrophosphatase SID6-306; pyrophosphate phospho-hydrolase 2; SID6-306|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
PPA2 involved in several pathways and played different roles in them. We selected most pathways PPA2 participated on our site, such as Oxidative phosphorylation, which may be useful for your reference. Also, other proteins which involved in the same pathway with PPA2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Oxidative phosphorylation||ATP5IA; ATP6V0A1A; NDUFA5; NDUFA12; NDUFA4L2; ATP6V0E2; Atp5g2; NDUFB8; MT-ND1; COX10|
PPA2 has several biochemical functions, for example, inorganic diphosphatase activity, magnesium ion binding, protein serine/threonine phosphatase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PPA2 itself. We selected most functions PPA2 had, and list some proteins which have the same functions with PPA2. You can find most of the proteins on our site.
|inorganic diphosphatase activity||PRUNE; PPA1; PPA2; PPA1A; LHPP; PPA1B|
|magnesium ion binding||ATP9A; MARK2; SRPK1; PI4K2A; SPHK1; NUDT18; THTPA; ZAK; PPA1B; SIK3|
|protein serine/threonine phosphatase activity||TIMM50; CTDNEP1; PPEF1; PPM1NB; PPM1H; CDKN3; PPP1R15B; PTEN; MTMR3; PPM1A|
PPA2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PPA2 here. Most of them are supplied by our site. Hope this information will be useful for your research of PPA2.
HTT; 15-deoxy-delta(12,14; ZWINT; MYC; COMT; SIRT4