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PPEF1

  • Official Full Name

    protein phosphatase, EF-hand calcium binding domain 1

  • Overview

    This gene encodes a member of the serine/threonine protein phosphatase with EF-hand motif family. The protein contains a protein phosphatase catalytic domain, and at least two EF-hand calcium-binding motifs in its C terminus. Although its substrate(s) is unknown, the encoded protein has been suggested to play a role in specific sensory neuron function and/or development. This gene shares high sequence similarity with the Drosophila retinal degeneration C (rdgC) gene. Several alternatively spliced transcript variants, each encoding a distinct isoform, have been described.
  • Synonyms

    PPEF1; protein phosphatase, EF-hand calcium binding domain 1; PPEF; serine/threonine-protein phosphatase with EF-hands 1; PPP7CA; protein phosphatase 7; catalytic subunit; alpha isozyme; serine/threonine protein phosphatase 7; serine/threonine-protein pho;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • Zebrafish
  • E.coli
  • HEK293
  • Mammalian Cell
  • GST
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human PPEF1-1878H Recombinant Human PPEF1, GST-tagged E.coli GST N-term-350aa
Human PPEF1-2980HCL Recombinant Human PPEF1 293 Cell Lysate HEK293 N/A
Human PPEF1-3062H Recombinant Human PPEF1 protein, His-tagged E.coli His 1-350 aa
Mouse PPEF1-13170M Recombinant Mouse PPEF1 Protein Mammalian Cell His
Mouse PPEF1-6974M-B Recombinant Mouse PPEF1 Protein Pre-coupled Magnetic Beads HEK293
Mouse PPEF1-6974M Recombinant Mouse PPEF1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat PPEF1-4598R Recombinant Rat PPEF1 Protein Mammalian Cell His
Rat PPEF1-4257R Recombinant Rat PPEF1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat PPEF1-4257R-B Recombinant Rat PPEF1 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish PPEF1-6474Z Recombinant Zebrafish PPEF1 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • PPEF1 Related Articles

PPEF1 involved in several pathways and played different roles in them. We selected most pathways PPEF1 participated on our site, such as Inactivation, recovery and regulation of the phototransduction cascade, Signal Transduction, The phototransduction cascade, which may be useful for your reference. Also, other proteins which involved in the same pathway with PPEF1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Inactivation, recovery and regulation of the phototransduction cascadeNMT2;NMT1A;METAP1;PPEF1;GUCA1E;METAP2A;METAP2B;RLN1;RGS9BP
Signal TransductionLRP12;RGS21;CDON;EDNRAB;ADCYAP1B;GPRC6A;GPR37B;RHOT2;RLBP1
The phototransduction cascadeMETAP2B;RGS9BP;NMT1B;RLN1;METAP2;PPEF1;NMT1A;CNGA1;METAP2A
Visual phototransductionMETAP2;APOA4A;MYO7AA;BCO2;LRP12;PPEF1;RLBP1A;RBP3;METAP1

PPEF1 has several biochemical functions, for example, calcium ion binding, iron ion binding, manganese ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PPEF1 itself. We selected most functions PPEF1 had, and list some proteins which have the same functions with PPEF1. You can find most of the proteins on our site.

Function Related Protein
calcium ion bindingTLL1;JAG1B;SCUBE2;AP1S2;PLA2G2F;CAPN11;PLA2G12B;PVALB;MGMT
iron ion bindingCYP2F2;KDM3A;CYP2R1;FAM125B;CALR;HIF1AN;CYP11B2;NOS1;BBOX1
manganese ion bindingPPM1B;LAP3;B4GALT7;FAM20C;B4GALT1;DCP2;ENDOU;MTPAP;DYRK2
protein bindingHSPA5;RGS20;OAZ3;ZFYVE1;USP8;CHN1;TMEM182;IGFBP3;USP22
protein serine/threonine phosphatase activityCTDNEP1;PPM1N;DUSP23A;PPM1AB;CDC14AB;PPM1B;PPM1K;PPP6C;MTMR3

PPEF1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PPEF1 here. Most of them are supplied by our site. Hope this information will be useful for your research of PPEF1.

Calm1

Yamaguchi, M; et al. The anti-apoptotic effect of regucalcin is mediated through multisignaling pathways. APOPTOSIS 18:1145-1153(2013).
Brunet, S; Scheuer, T; et al. Increased intracellular magnesium attenuates beta-adrenergic stimulation of the cardiac Ca(V)1.2 channel. JOURNAL OF GENERAL PHYSIOLOGY 141:85-94(2013).
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