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PRPF4B

Official Full Name

PRP4 pre-mRNA processing factor 4 homolog B
Overview

Pre-mRNA splicing occurs in two sequential transesterification steps, and the protein encoded by this gene is thought to be involved in pre-mRNA splicing and in signal transduction. This protein belongs to a kinase family that includes serine/arginine-rich protein-specific kinases and cyclin-dependent kinases (CDKs). This protein is regarded as a CDK-like kinase (Clk) with homology to mitogen-activated protein kinases (MAPKs).
Synonyms

PRPF4B; PRP4 pre-mRNA processing factor 4 homolog B (yeast); serine/threonine-protein kinase PRP4 homolog; KIAA0536; PR4H; Prp4; PRP4 kinase; protein-serine/threonine kinase; PRP4 pre-mRNA-processing factor 4 homolog; dJ1013A10.1 (PRP4 protein kinase homo;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse
Rat

Source

E.coli
HEK293
Mammalian Cell

Tag

His
His (Fc)
Avi
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	PRPF4B-1978H	Recombinant Human PRPF4B, His-tagged	E.coli	His	668-1007aa	$319 / 25ug
Human	PRPF4B-2824HCL	Recombinant Human PRPF4B 293 Cell Lysate	HEK293	N/A		Inquiry
Mouse	PRPF4B-13456M	Recombinant Mouse PRPF4B Protein	Mammalian Cell	His		Inquiry
Mouse	PRPF4B-7147M-B	Recombinant Mouse PRPF4B Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Mouse	PRPF4B-7147M	Recombinant Mouse PRPF4B Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Rat	PRPF4B-4720R	Recombinant Rat PRPF4B Protein	Mammalian Cell	His		Inquiry
Rat	PRPF4B-4379R	Recombinant Rat PRPF4B Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Rat	PRPF4B-4379R-B	Recombinant Rat PRPF4B Protein Pre-coupled Magnetic Beads	HEK293			Inquiry

Involved Pathway
Protein Function
Interacting Protein

PRPF4B involved in several pathways and played different roles in them. We selected most pathways PRPF4B participated on our site, such as mRNA processing, which may be useful for your reference. Also, other proteins which involved in the same pathway with PRPF4B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
mRNA processing	QK;DHX15;PTBP1A;RBMS3;SFRS3A;METTL3;MCTS2;PRPF8;RBM5

PRPF4B has several biochemical functions, for example, ATP binding, poly(A) RNA binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PRPF4B itself. We selected most functions PRPF4B had, and list some proteins which have the same functions with PRPF4B. You can find most of the proteins on our site.

Function	Related Protein
ATP binding	PLK2;MKI67;PKZ;MSH4;SLFN5;PRKACA;NLRP4B;PAN3;YARS2
poly(A) RNA binding	NPM1;SOSTDC1B;TRIM25;NME1;SUPT6H;DDX49;MRPS24;CHST13;DDX27
protein binding	PRDM10;STAP2;TCTEX1D1;DIS3;REG3A;KRTAP5-9;ELMO1;BARD1;ATF5
protein kinase activity	EPHB2B;CAMK2D2;MMD;STK17B;ERBB3A;PRKG2;MKNK2B;TAOK1;TNIK
protein serine/threonine kinase activity	ROCK2;ACVR1BA;CAMK1GA;CAMK2D;PKN1B;GM4922;BMPR2A;STK38;CDK16

PRPF4B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PRPF4B here. Most of them are supplied by our site. Hope this information will be useful for your research of PRPF4B.

KLF13; gag; YWHAG; PRPF4; USP39; POLR3F; ARRB2