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PSMA4

  • Official Full Name

    proteasome (prosome, macropain) subunit, alpha type, 4

  • Overview

    The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene.
  • Synonyms

    PSMA4; proteasome (prosome, macropain) subunit, alpha type, 4; proteasome subunit alpha type-4; HC9; HsT17706; Macropain subunit C9; MGC111191; MGC12467; MGC24813; Multicatalytic endopeptidase complex subunit C9; Proteasome (prosome macropain) subunit alpha type 4; Proteasome alpha 4 subunit; Proteasome component C9; Proteasome subunit alpha type 4; Proteasome subunit HC9; Proteasome subunit L; PSA4_HUMAN; PSC9; PSMA 4; OTTHUMP00000185020;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Cynomolgus Monkey
  • Human
  • Mouse
  • Rat
  • Rhesus Macaque
  • Staphylococcus aureus (strain Mu3 / ATCC 700698)
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • Mammalian Cell
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human PSMA4-1565H Recombinant Human Proteasome (prosome, macropain) Subunit, Alpha Type, 4, His-tagged E.coli His
Human PSMA4-2012H Recombinant Human PSMA4, GST-tagged E.coli GST 1-237aa
Human PSMA4-2778HCL Recombinant Human PSMA4 293 Cell Lysate HEK293 N/A
Human PSMA4-1960H Recombinant Human PSMA4 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human PSMA4-2843H Recombinant Human PSMA4 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human PSMA4-2634H Recombinant Human PSMA4 Protein, His-tagged E.coli N-His Met1-Lys261
Mouse PSMA4-13564M Recombinant Mouse PSMA4 Protein Mammalian Cell His
Mouse PSMA4-7206M Recombinant Mouse PSMA4 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Psma4-5174M Recombinant Mouse Psma4 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse PSMA4-7206M-B Recombinant Mouse PSMA4 Protein Pre-coupled Magnetic Beads HEK293
Rat PSMA4-4766R Recombinant Rat PSMA4 Protein Mammalian Cell His
Rat PSMA4-4425R Recombinant Rat PSMA4 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat PSMA4-4425R-B Recombinant Rat PSMA4 Protein Pre-coupled Magnetic Beads HEK293
Cynomolgus Monkey PSMA4-818C Recombinant Cynomolgus PSMA4 Protein, His-tagged Mammalian Cell His
Cynomolgus Monkey PSMA4-561C-B Recombinant Cynomolgus Monkey PSMA4 Protein Pre-coupled Magnetic Beads HEK293
Cynomolgus Monkey PSMA4-561C Recombinant Cynomolgus Monkey PSMA4 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque PSMA4-3650R Recombinant Rhesus monkey PSMA4 Protein, His-tagged Mammalian Cell His
Rhesus Macaque PSMA4-3468R Recombinant Rhesus Macaque PSMA4 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque PSMA4-3468R-B Recombinant Rhesus Macaque PSMA4 Protein Pre-coupled Magnetic Beads HEK293
Staphylococcus aureus (strain Mu3 / ATCC 700698) psmA4-4505S Recombinant Staphylococcus aureus (strain Mu3 / ATCC 700698) psmA4 protein E.coli N/A 1-20aa
Zebrafish PSMA4-12727Z Recombinant Zebrafish PSMA4 Mammalian Cell His
Chicken PSMA4-4182C Recombinant Chicken PSMA4 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

PSMA4 involved in several pathways and played different roles in them. We selected most pathways PSMA4 participated on our site, such as Proteasome, which may be useful for your reference. Also, other proteins which involved in the same pathway with PSMA4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
ProteasomePSMB1;PSMA4;PSMD11;PSMB2;PSME4B;PSMD6;PSMC1A;PSMD8;PSMD4A

PSMA4 has several biochemical functions, for example, endopeptidase activity, protein binding, threonine-type endopeptidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PSMA4 itself. We selected most functions PSMA4 had, and list some proteins which have the same functions with PSMA4. You can find most of the proteins on our site.

Function Related Protein
endopeptidase activityPSMB9;KLK1B11;PSMB8;ATG4B;KLK1B1;FAP;APH1B;TPP1;PARL
protein bindingSCNN1G;DDX41;ASGR2;TYK2;NAV1;ASMTL;SDHB;TFAP2A;NITR9
threonine-type endopeptidase activityPSMB9A;PSMB3;PSMB5;PSMA1;PSMA3;PSMB2;PSMA7;PSMB8F;PSMA6B

PSMA4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PSMA4 here. Most of them are supplied by our site. Hope this information will be useful for your research of PSMA4.

PSMA2; PSMA7; PSMA1; PSMA3

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