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Official Full Name proteasome (prosome, macropain) subunit, alpha type, 4
Background The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Synonyms PSMA4; proteasome (prosome, macropain) subunit, alpha type, 4; proteasome subunit alpha type-4; HC9; HsT17706; Macropain subunit C9; MGC111191; MGC12467; MGC24813; Multicatalytic endopeptidase complex subunit C9; Proteasome (prosome macropain) subunit alpha type 4; Proteasome alpha 4 subunit; Proteasome component C9; Proteasome subunit alpha type 4; Proteasome subunit HC9; Proteasome subunit L; PSA4_HUMAN; PSC9; PSMA 4; OTTHUMP00000185020
    • Species :
    • Chicken
    • Cynomolgus Monkey
    • Human
    • Mouse
    • Rat
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human PSMA4-1565H Recombinant Human Proteasome (prosome, macropain) Subunit, Alpha Type, 4, His-tagged E.coli His
    Human PSMA4-2012H Recombinant Human PSMA4, GST-tagged E.coli GST
    Human PSMA4-2778HCL Recombinant Human PSMA4 293 Cell Lysate HEK293 N/A
    Mouse PSMA4-13564M Recombinant Mouse PSMA4 Protein Mammalian Cell His
    Rat PSMA4-4766R Recombinant Rat PSMA4 Protein Mammalian Cell His
    Cynomolgus Monkey PSMA4-818C Recombinant Cynomolgus PSMA4 Protein, His-tagged Mammalian Cell His
    Rhesus Macaque PSMA4-3650R Recombinant Rhesus monkey PSMA4 Protein, His-tagged Mammalian Cell His
    Chicken PSMA4-4182C Recombinant Chicken PSMA4 Mammalian Cell His
    Zebrafish PSMA4-12727Z Recombinant Zebrafish PSMA4 Mammalian Cell His

    psma4 involved in several pathways and played different roles in them. We selected most pathways psma4 participated on our site, such as Proteasome, which may be useful for your reference. Also, other proteins which involved in the same pathway with psma4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Proteasome PSMD12; PSMA1; PSMF1; PSMB1; PSMB5; PSMA3; PSMC5; PSMD3; PSME1; SHFM1

    psma4 has several biochemical functions, for example, endopeptidase activity, protein binding, threonine-type endopeptidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by psma4 itself. We selected most functions psma4 had, and list some proteins which have the same functions with psma4. You can find most of the proteins on our site.

    Function Related Protein
    endopeptidase activity TMEM59; KLK1B4; FAP; CPNE1; PSMB11; KLK1B8; MMP9; P4HB; HTRA4; ADAMTS3
    protein binding KDRL; CXXC11; CDC7; MKI67IP; C9orf116; RPL27A; KPNA5; HACL1; PRL2C2; KLRC1
    threonine-type endopeptidase activity PSMA6A; PSMB9; PSMB9A; PSMA3; PSMA6B; PSMA6; PSMB2; PSMA7; PSMB3; PSMA2

    psma4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with psma4 here. Most of them are supplied by our site. Hope this information will be useful for your research of psma4.


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