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Official Full Name proteasome (prosome, macropain) subunit, alpha type, 8
Background The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity (By similarity). This may be a testis-specific subunit.
Synonyms PSMA8; proteasome (prosome, macropain) subunit, alpha type, 8; proteasome subunit alpha type-7-like; MGC26605; PSMA7L; Proteasome subunit alpha type 7 like; PSA7L_HUMAN; PSMA 7L; PSMA 8; PSMA8 proteasome (prosome macropain) subunit alpha type 8; PSMA8 proteasome subunit alpha type 8
    • Species :
    • Human
    • Mouse
    • Zebrafish
    • Source :
    • E.coli
    • Mammalian Cell
    • Tag :
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human PSMA8-1320H Recombinant Human Proteasome (prosome, macropain) Subunit, Alpha Type, 8, His-tagged E.coli His
    Human PSMA8-1429HCL Recombinant Human PSMA8 cell lysate N/A
    Human PSMA8-2015H Recombinant Human PSMA8, His-tagged E.coli His
    Human PSMA8-30593TH Recombinant Human PSMA8, His-tagged E.coli His
    Mouse PSMA8-13568M Recombinant Mouse PSMA8 Protein Mammalian Cell His
    Zebrafish PSMA8-12382Z Recombinant Zebrafish PSMA8 Mammalian Cell His

    psma8 involved in several pathways and played different roles in them. We selected most pathways psma8 participated on our site, such as APC/C-mediated degradation of cell cycle proteins, APC/C:Cdc20 mediated degradation of Securin, APC/C:Cdc20 mediated degradation of mitotic proteins, which may be useful for your reference. Also, other proteins which involved in the same pathway with psma8 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    APC/C-mediated degradation of cell cycle proteins PSMD5; PSMD10; ANAPC10; UBE2C; AURKB; PSMA8; PSMD14; PSMD9; NEK2; PSME3
    APC/C:Cdc20 mediated degradation of Securin ANAPC10; PSMD10; PSMD5; UBE2C; PSMA8; PSMD14; PSMD9; PSME3
    APC/C:Cdc20 mediated degradation of mitotic proteins ANAPC10; PSMD10; NEK2; PSMD14; PSME3; UBE2C; PSMA8; PSMD9; PSMD5
    APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 AURKB; PSMA8; PSMD9; PSMD14; ANAPC10; PSMD10; PSMD5; PSME3; UBE2C
    APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint PSMD14; PSMA8; PSMD10; PSME3; PSMD5; UBE2C; ANAPC10; PSMD9; NEK2
    ARMS-mediated activation PSMD10; WDR83; JAK3; DUSP5; PEA15A; DUSP1; MARK3; PAQR3A; PSMD14; SPTBN1
    AUF1 (hnRNP D0) binds and destabilizes mRNA PSMD10; EIF4G1; HNRNPD; PSME3; PSMA8; PSMD9; PSMD5; PSMD14
    Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins NEK2; UBE2C; PSMD14; ANAPC10; PSMD10; PSMA8; PSME3; PSMD9; PSMD5

    psma8 has several biochemical functions, for example, endopeptidase activity, threonine-type endopeptidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by psma8 itself. We selected most functions psma8 had, and list some proteins which have the same functions with psma8. You can find most of the proteins on our site.

    Function Related Protein
    endopeptidase activity CPNE1; RHBDD1; MMP12; PSMB10; PSMB9B; PSMA6B; PSMA7; PSMA1; PSMB1; AP1S2
    threonine-type endopeptidase activity TASP1; PSMB3; PSMA6; PSMA2; PSMA8; PSMA5; PSMB4; PSMB7; PSMB2; PSMB10

    psma8 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with psma8 here. Most of them are supplied by our site. Hope this information will be useful for your research of psma8.

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