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PSMA8

Official Full Name

proteasome (prosome, macropain) subunit, alpha type, 8
Overview

The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity (By similarity). This may be a testis-specific subunit.
Synonyms

PSMA8; proteasome (prosome, macropain) subunit, alpha type, 8; proteasome subunit alpha type-7-like; MGC26605; PSMA7L; Proteasome subunit alpha type 7 like; PSA7L_HUMAN; PSMA 7L; PSMA 8; PSMA8 proteasome (prosome macropain) subunit alpha type 8; PSMA8 proteasome subunit alpha type 8;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse
Zebrafish

Source

E.coli
HEK293
Mammalian Cell

Tag

His
His (Fc)
Avi
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	PSMA8-2015H	Recombinant Human PSMA8, His-tagged	E.coli	His	1-250aa	$319 / 25ug
Human	PSMA8-1320H	Recombinant Human Proteasome (prosome, macropain) Subunit, Alpha Type, 8, His-tagged	E.coli	His		Inquiry
Human	PSMA8-30593TH	Recombinant Human PSMA8, His-tagged	E.coli	His	250 amino acids	Inquiry
Human	PSMA8-1429HCL	Recombinant Human PSMA8 cell lysate		N/A		Inquiry
Mouse	PSMA8-13568M	Recombinant Mouse PSMA8 Protein	Mammalian Cell	His		Inquiry
Mouse	PSMA8-7208M	Recombinant Mouse PSMA8 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Mouse	PSMA8-7208M-B	Recombinant Mouse PSMA8 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Zebrafish	PSMA8-12382Z	Recombinant Zebrafish PSMA8	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein

PSMA8 involved in several pathways and played different roles in them. We selected most pathways PSMA8 participated on our site, such as APC/C-mediated degradation of cell cycle proteins, APC/C:Cdc20 mediated degradation of Securin, APC/C:Cdc20 mediated degradation of mitotic proteins, which may be useful for your reference. Also, other proteins which involved in the same pathway with PSMA8 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
APC/C-mediated degradation of cell cycle proteins	CDK2;PSMD9;PSMD10;NEK2;PSMD14;PSMA8;UBE2C;PSMD5;PSME3
APC/C:Cdc20 mediated degradation of Securin	PSMA8;UBE2C;PSMD5;PSME3;PSMD14;ANAPC10;PSMD10;PSMD9
APC/C:Cdc20 mediated degradation of mitotic proteins	NEK2;PSME3;PSMD14;ANAPC10;PSMD10;PSMD9;UBE2C;PSMD5;PSMA8
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1	PSMA8;PSME3;PSMD14;PSMD5;PSMD9;PSMD10;UBE2C;ANAPC10;AURKB
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint	PSMA8;PSMD5;PSMD9;PSMD14;NEK2;PSMD10;ANAPC10;PSME3;UBE2C
ARMS-mediated activation	SPTB;DUSP10;DUSP7;DUSP9;FGF20A;NTF7;CRK;PTPRA;CSF2RB
AUF1 (hnRNP D0) binds and destabilizes mRNA	PSME3;PSMD14;HNRNPD;EIF4G1;PSMA8;PSMD9;PSMD10;PSMD5
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins	PSMD10;UBE2C;ANAPC10;PSMD14;NEK2;PSME3;PSMA8;PSMD9;PSMD5

PSMA8 has several biochemical functions, for example, endopeptidase activity, threonine-type endopeptidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PSMA8 itself. We selected most functions PSMA8 had, and list some proteins which have the same functions with PSMA8. You can find most of the proteins on our site.

Function	Related Protein
endopeptidase activity	PSMA6B;TPP1;PARL;ADAMTS3;PSEN2;ACE;PSMB9B;ATG4B;PSMA7
threonine-type endopeptidase activity	PSMA3;PSMA7;PSMB5;PSMA4;PSMB9A;PSMB8;PSMA6;PSMB1;PSMA2

PSMA8 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PSMA8 here. Most of them are supplied by our site. Hope this information will be useful for your research of PSMA8.