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PXK

Official Full Name

PX domain containing serine/threonine kinase
Overview

PXK binds to the Na,K-ATPase beta-1 (ATP1B1; MIM 182330) and beta-3 (ATP1B3; MIM 601867) subunits and modulates both;Na,K-ATPase enzymatic and ion pump activities (Mao et al., 2005 (PubMed 16135750)).
Synonyms

PXK; PX domain containing serine/threonine kinase; PX domain-containing protein kinase-like protein; FLJ20335; K-ATPase; Modulator of Na; Modulator of Na K ATPase; Modulator of Na K ATPase long form; MONaKA; PX domain containing protein kinase like protein; PX ser/thr kinase v2; PX serine/threonine kinase; PXK_HUMAN; OTTHUMP00000214170; OTTHUMP00000214171; OTTHUMP00000214173; OTTHUMP00000214175; OTTHUMP00000214179; modulator of Na,K-ATPase long form;

Type

Cell & Tissue Lysates
Recombinant Proteins
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse
Rat
Zebrafish

Source

HEK293
HEK293T
Insect Cell
Mammalian Cell

Tag

His
His (Fc)
Avi
GST
Myc
DDK
N/A
No tag

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	PXK-2653HCL	Recombinant Human PXK 293 Cell Lysate	HEK293	N/A		Inquiry
Human	PXK-0149H	Recombinant Human PXK Protein (A2-G578), Tag Free	Insect Cell	No tag	A2-G578	Inquiry
Human	PXK-0150H	Recombinant Human PXK Protein (A2-G578), His/GST tagged	Insect Cell	His/GST	A2-G578	Inquiry
Mouse	PXK-13740M	Recombinant Mouse PXK Protein	Mammalian Cell	His		Inquiry
Mouse	PXK-7313M-B	Recombinant Mouse PXK Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Mouse	Pxk-5266M	Recombinant Mouse Pxk Protein, Myc/DDK-tagged	HEK293T	Myc/DDK		Inquiry
Mouse	PXK-7313M	Recombinant Mouse PXK Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Rat	PXK-4853R	Recombinant Rat PXK Protein	Mammalian Cell	His		Inquiry
Rat	PXK-4512R	Recombinant Rat PXK Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Rat	PXK-4512R-B	Recombinant Rat PXK Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Zebrafish	PXK-5217Z	Recombinant Zebrafish PXK	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein

PXK involved in several pathways and played different roles in them. We selected most pathways PXK participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with PXK were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

PXK has several biochemical functions, for example, NOT ATP binding, actin binding, NOT nucleotide binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PXK itself. We selected most functions PXK had, and list some proteins which have the same functions with PXK. You can find most of the proteins on our site.

Function	Related Protein
NOT ATP binding	TRIB1;PXK
actin binding	ABLIM1;SSH2;LCP1;ACTR2B;MYO15;MSRB1;EPB41L1;SPIRE1A;IPP
NOT nucleotide binding	TRIB2;PXK
phosphatidylinositol binding	NCF1;ARHGAP32;SNX32;SNX8;SNX19A;SNX27B;SNX12;MTM1;SNX15
protein C-terminus binding	XRCC4;PDZD11;MYO1C;PHB2;SDC1;VGLL2;YEATS4;KCNJ11;ARL6IP5
NOT protein kinase activity	STRADB;MLKL;TRIB1;TRIB2;HSPB8;STRADA;PXK

PXK has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PXK here. Most of them are supplied by our site. Hope this information will be useful for your research of PXK.

YBX3; FBL; HNRNPA0; ALYREF