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RASAL1

Official Full Name

RAS protein activator like 1 (GAP1 like)
Overview

The protein encoded by this gene is member of the GAP1 family of GTPase-activating proteins. These proteins stimulate;the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the;protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS,;thereby allowing control of cellular proliferation and differentiation. This particular family member contains domains;which are characteristic of the GAP1 subfamily of RasGAP proteins but, in contrast to the other GAP1 family members,;this protein is strongly and selectively expressed in endocrine tissues. Alternatively spliced transcript variants;that encode different isoforms have been described.
Synonyms

RASAL1; RAS protein activator like 1 (GAP1 like); rasGAP-activating-like protein 1; RASAL; GAP1 like protein; MRASAL; RAS GTPase activating protein like; rasGAP activating like protein 1; RASGAP1 LIKE; RASL1_HUMAN;

Species	Cat.#	Product name	Source (Host)	Tag	Price
Human	RASAL1-1475HCL	Recombinant Human RASAL1 cell lysate		N/A	Inquiry
Mouse	RASAL1-13943M	Recombinant Mouse RASAL1 Protein	Mammalian Cell	His	Inquiry
Mouse	RASAL1-7430M	Recombinant Mouse RASAL1 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi	Inquiry
Mouse	RASAL1-7430M-B	Recombinant Mouse RASAL1 Protein Pre-coupled Magnetic Beads	HEK293		Inquiry

Involved Pathway
Protein Function
Interacting Protein

RASAL1 involved in several pathways and played different roles in them. We selected most pathways RASAL1 participated on our site, such as Ras signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with RASAL1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Ras signaling pathway	KSR2;SHC3;PLD2;MAPK1;INS2;Fasl;RALB;MAPK9;PLA2G2E

RASAL1 has several biochemical functions, for example, GTPase activator activity, metal ion binding, phospholipid binding. Some of the functions are cooperated with other proteins, some of the functions could acted by RASAL1 itself. We selected most functions RASAL1 had, and list some proteins which have the same functions with RASAL1. You can find most of the proteins on our site.

Function	Related Protein
GTPase activator activity	RALBP1;PGAM5;RGS6;RGS12;TBC1D5;MYO9B;RANBP1;GDI1;DOCK1
metal ion binding	KLF2;RARAB;AGBL4;THOP1;FOLH1;ZNF496;ELAC1;Car4;BTR12
phospholipid binding	NUP35;AMPH;NBEAA;VAMP2;BPIFC;SEC14L2;F3;DGKA;SPTB

RASAL1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RASAL1 here. Most of them are supplied by our site. Hope this information will be useful for your research of RASAL1.