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RASD2

Official Full Name

RASD family, member 2
Overview

Ras family proteins are molecular switches,Which are mediated by extracellular signals and regulate intracellular signaling pathways, thereby controlling a plethora of biological functions such as cell growth, gene transcription, mRNA stability and translation, cytoskeleton organization, peptide trafficking and secrection. Ras proteins are also involved in synaptic plasticity, learning, and memory in the central nervous system.As a member of the RASD subfamily of the Ras-related GTP-binding protein superfamily, Rhes is predominantly expressed in the striatal region of the brain,Where it reported to influence brain development and function. It is thought that the activation and expression of the Rhes gene is mediated by thyroid hormones in the brain. In humans, a lack of such hormones is known to cause cretinism. Additionally, Rhes -/- knockout mice display marked behavioral abnormalities, a gender-dependent increase in anxiety levels, and a clear deficit in motor coordination.
Synonyms

RASD2; RASD family, member 2; GTP-binding protein Rhes; MGC:4834; Ras homolog enriched in striatum; Rhes; TEM2; tumor endothelial marker 2;

Species	Cat.#	Product name	Source (Host)	Tag	Price
Human	RASD2-2508HCL	Recombinant Human RASD2 293 Cell Lysate	HEK293	N/A	Inquiry
Human	RASD2-5922H	Recombinant Human RASD2 Protein, Myc/DDK-tagged, C13 and N15-labeled	HEK293T	Myc/DDK	Inquiry
Rat	RASD2-4934R	Recombinant Rat RASD2 Protein	Mammalian Cell	His	Inquiry
Rat	RASD2-4593R	Recombinant Rat RASD2 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi	Inquiry
Rat	RASD2-4593R-B	Recombinant Rat RASD2 Protein Pre-coupled Magnetic Beads	HEK293		Inquiry

Involved Pathway
Protein Function
Interacting Protein

RASD2 involved in several pathways and played different roles in them. We selected most pathways RASD2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with RASD2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

RASD2 has several biochemical functions, for example, G-protein beta-subunit binding, GTP binding, GTPase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by RASD2 itself. We selected most functions RASD2 had, and list some proteins which have the same functions with RASD2. You can find most of the proteins on our site.

Function	Related Protein
G-protein beta-subunit binding	CCT5;F2R;RGS9;RASD2;GNG2;OPRM1;GNG13;F2RL1;RGS11
GTP binding	RAB30;RAB40AL;SEPT10;ARL5A;ARL14;GNA13B;TUBA2;TUBA3C;ADSSL1
GTPase activity	GNB1;RASD2;MXA;CDC42;ARL4D;RAB11BB;SEPT5;RALAA;RAB33B
ubiquitin conjugating enzyme binding	RNF144A;TOLLIP;TRAF6;SIAH2;RNF144AB;GRIK2;RNF19B;MARCH6;UBE2V1

RASD2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RASD2 here. Most of them are supplied by our site. Hope this information will be useful for your research of RASD2.

RABAC1