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RBM28

Official Full Name

RNA binding motif protein 28
Overview

The protein encoded by this gene is a specific nucleolar component of the spliceosomal small nuclear ribonucleoprotein (snRNP)complexes . It specifically associates with U1, U2, U4, U5, and U6 small nuclear RNAs (snRNAs), possibly coordinating their transition through the nucleolus. Mutation in this gene causes alopecia, progressive neurological defects, and endocrinopathy (ANE syndrome), a pleiotropic and clinically heterogeneous disorder. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Synonyms

RBM28; RNA binding motif protein 28; RNA-binding protein 28; FLJ10377; 2810480G15Rik;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse
Zebrafish

Source

E.coli
HEK293
Mammalian Cell

Tag

His
His (Fc)
Avi
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	RBM28-2213H	Recombinant Human RBM28, His-tagged	E.coli	His	408-756aa	$319 / 25ug
Human	RBM28-2475HCL	Recombinant Human RBM28 293 Cell Lysate	HEK293	N/A		Inquiry
Mouse	RBM28-14000M	Recombinant Mouse RBM28 Protein	Mammalian Cell	His		Inquiry
Mouse	RBM28-7477M	Recombinant Mouse RBM28 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Mouse	RBM28-7477M-B	Recombinant Mouse RBM28 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Zebrafish	RBM28-10649Z	Recombinant Zebrafish RBM28	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein

RBM28 involved in several pathways and played different roles in them. We selected most pathways RBM28 participated on our site, such as Ribosome biogenesis in eukaryotes, which may be useful for your reference. Also, other proteins which involved in the same pathway with RBM28 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Ribosome biogenesis in eukaryotes	BMS1;cka1;ACK2;WDR43;WDR3;UTP15;HEATR1;CIRH1A;NHP2L1B

RBM28 has several biochemical functions, for example, nucleotide binding, poly(A) RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by RBM28 itself. We selected most functions RBM28 had, and list some proteins which have the same functions with RBM28. You can find most of the proteins on our site.

Function	Related Protein
nucleotide binding	PABPC3;CELF5A;ROCK2A;EEF1A1A;PSMC1A;TNRC6B;ATP8B1;DCLK3;ABCA5
poly(A) RNA binding	MRPL37;CKAP4;D19BWG1357E;SRPK2;PRPF38B;BCLAF1;WBSCR22;MDH2;HIST1H1B

RBM28 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RBM28 here. Most of them are supplied by our site. Hope this information will be useful for your research of RBM28.

dsdna_dcmdg:dcmdg; NOP56; GABARAP; ESR1; RPL10; MNDA; KIF11; GABARAPL2; HNRNPU; IFI16; ESR2; HDAC11; SORT1; Rrbp1