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RD3

Official Full Name

retinal degeneration 3
Overview

This gene encodes a retinal protein that is associated with promyelocytic leukemia-gene product (PML) bodies in the nucleus. Mutations in this gene cause Leber congenital amaurosis type 12, a disease that results in retinal degeneration. Alternative splicing results in multiple transcript variants.
Synonyms

RD3; retinal degeneration 3; C1orf36, chromosome 1 open reading frame 36; protein RD3; LCA12; C1orf36; chromosome 1 open reading frame 36;

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	RD3-2234H	Recombinant Human RD3, His-tagged	E.coli	His	1-195aa	$319 / 25ug
Human	RD3-2441HCL	Recombinant Human RD3 293 Cell Lysate	HEK293	N/A		Inquiry
Human	RD3-5664H	Recombinant Human RD3 Protein, Myc/DDK-tagged, C13 and N15-labeled	HEK293T	Myc/DDK		Inquiry
Mouse	Rd3-5442M	Recombinant Mouse Rd3 Protein, Myc/DDK-tagged	HEK293T	Myc/DDK		Inquiry
Zebrafish	RD3-5120Z	Recombinant Zebrafish RD3	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein
RD3 Related Articles

RD3 involved in several pathways and played different roles in them. We selected most pathways RD3 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with RD3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

RD3 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by RD3 itself. We selected most functions RD3 had, and list some proteins which have the same functions with RD3. You can find most of the proteins on our site.

Function	Related Protein
protein binding	VEGFC;CUL5;ZNF230;UNKL;IGSF1;NAT10;TCEB3;CD8B;EEA1

RD3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RD3 here. Most of them are supplied by our site. Hope this information will be useful for your research of RD3.

EHMT2; EIF2B1

Hara, M; Hirokawa, K; et al. Isoform transition from four-repeat to three-repeat tau underlies dendrosomatic and regional progression of neurofibrillary pathology. ACTA NEUROPATHOLOGICA 125:565-579(2013).

Uchihara, T; Hara, M; et al. Tangle evolution linked to differential 3-and 4-repeat tau isoform deposition: a double immunofluorolabeling study using two monoclonal antibodies. HISTOCHEMISTRY AND CELL BIOLOGY 137:261-267(2012).