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RHAG

  • Official Full Name

    Rh-associated glycoprotein

  • Overview

    The protein encoded by this gene is erythrocyte-specific and is thought to be part of a membrane channel that transports ammonium and carbon dioxide across the blood cell membrane. The encoded protein appears to interact with Rh blood group antigens and Rh30 polypeptides. Defects in this gene are a cause of regulator type Rh-null hemolytic anemia (RHN), or Rh-deficiency syndrome.
  • Synonyms

    RHAG; Rh-associated glycoprotein; Rhesus blood group associated glycoprotein; ammonium transporter Rh type A; CD241; RH50A; SLC42A1; Abnormal Rhesus blood group associated glycoprotein; CD241 antigen; Erythrocyte membrane glycoprotein Rh50; Erythrocyte plasma membrane 50 kDa glycoprotein; Rh associated glycoprotein; RH2; RH50; Rh50 glycoprotein; Rh50 GP; Rhesus blood group associated ammonia channel; rh type A glycoprotein; rh family type A glycoprotein; Rhesus associated polypeptide, 50-KD; Rhesus blood group-associated glycoprotein; rhesus blood group family type A glycoprotein; rhesus blood group-associated ammonia channel; Rh50GP;

  • Cell & Tissue Lysates
  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rat
  • Rattus norvegicus (Rat)
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • E.coli expression system
  • HEK293
  • Mammalian Cell
  • His
  • His (Fc)
  • Avi
  • His|T7
  • N/A
  • Tag
  • Free
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human RHAG-2366HCL Recombinant Human RHAG 293 Cell Lysate HEK293 N/A
Mouse RHAG-14153M Recombinant Mouse RHAG Protein Mammalian Cell His
Mouse RHAG-7573M Recombinant Mouse RHAG Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse RHAG-7573M-B Recombinant Mouse RHAG Protein Pre-coupled Magnetic Beads HEK293
Rat Rhag-1840R Recombinant Rat Rhag protein, His & T7-tagged E.coli His/T7 Ala251~Val450 (Accession # Q7TNK7)
Rat RHAG-5025R Recombinant Rat RHAG Protein Mammalian Cell His
Rat RHAG-4684R Recombinant Rat RHAG Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat RHAG-4684R-B Recombinant Rat RHAG Protein Pre-coupled Magnetic Beads HEK293
Rattus norvegicus (Rat) RFL35348RF Recombinant Full Length Rat Ammonium Transporter Rh Type A(Rhag) Protein, Tag-Free E.coli expression system Tag-Free Full Length (1-450)
Rhesus Macaque RHAG-3879R Recombinant Rhesus monkey RHAG Protein, His-tagged Mammalian Cell His
Rhesus Macaque RHAG-3696R-B Recombinant Rhesus Macaque RHAG Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque RHAG-3696R Recombinant Rhesus Macaque RHAG Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Zebrafish RHAG-12107Z Recombinant Zebrafish RHAG Mammalian Cell His
Chicken RHAG-6034C Recombinant Chicken RHAG Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • RHAG Related Articles

RHAG involved in several pathways and played different roles in them. We selected most pathways RHAG participated on our site, such as Erythrocytes take up carbon dioxide and release oxygen, Erythrocytes take up oxygen and release carbon dioxide, Metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with RHAG were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Erythrocytes take up carbon dioxide and release oxygenRHAG;SLC4A1B;AQP1A.2;AQP1A.1;SLC4A1A
Erythrocytes take up oxygen and release carbon dioxideAQP1A.1;AQP1A.2;SLC4A1B;SLC4A1A;RHAG
MetabolismGSTK1;CIAPIN1;CYP2A7;ETFDH;YAP1;FABP11B;LYRM4;GRHL1;DCT
O2/CO2 exchange in erythrocytesSLC4A1A;AQP1A.1;RHAG;SLC4A1B;AQP1A.2
Rhesus glycoproteins mediate ammonium transport.RHCGB;RHCG;RHAG;RHCGA;RHCGL1;RHCG2A;RHBG
SLC-mediated transmembrane transportSLC2A6;SLC44A5B;SLC6A7;SLC9A8;SLC30A8;SLC6A6A;SLC5A6B;SLC4A4A;SLC5A11
Transmembrane transport of small moleculesSLC35A1;SLCO2B1;LCN9;APOD;TTYH2;TRPC5;SLC2A13;AQP3A;DMTN
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compoundsSLC30A8;SLC13A1;SLC6A19B;SLC6A15;RHCGL1;SLC2A13B;CP;SLC39A6;SLC5A2

RHAG has several biochemical functions, for example, ammonium transmembrane transporter activity, ankyrin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by RHAG itself. We selected most functions RHAG had, and list some proteins which have the same functions with RHAG. You can find most of the proteins on our site.

Function Related Protein
ammonium transmembrane transporter activityRHBG;AQP1;AQP1A.2;RHAG;RHCG;RHCGA;RHCGL1;RHD;AQP1A.1
ankyrin bindingCDH1;KCNJ11;OBSCN;ATP1A1;PLEC;KCNQ2;KCTD6;RHCG;SLC4A1

RHAG has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RHAG here. Most of them are supplied by our site. Hope this information will be useful for your research of RHAG.

Wood, CM; Nawata, CM; et al. Rh proteins and NH4+-activated Na+-ATPase in the Magadi tilapia (Alcolapia grahami), a 100% ureotelic teleost fish. JOURNAL OF EXPERIMENTAL BIOLOGY 216:2998-3007(2013).
Hsu, K; Lee, TY; et al. Expression of the Rh/RhAG complex is reduced in Mi.III erythrocytes. VOX SANGUINIS 102:221-227(2012).
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