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RIMS1

  • Official Full Name

    regulating synaptic membrane exocytosis 1

  • Overview

    The protein encoded by this gene is a RAS gene superfamily member that regulates synaptic vesicle exocytosis. The encoded protein may be part of the protein scaffold of the cell. Defects in this gene are a cause of cone-rod dystrophy type 7 (CORD7). Several transcript variants encoding different isoforms have been found for this gene.
  • Synonyms

    RIMS1; regulating synaptic membrane exocytosis 1; CORD7, RAB3 interacting protein 2 , RAB3IP2; regulating synaptic membrane exocytosis protein 1; KIAA0340; Rab3 interacting molecule; RIM; RIM1; RAB3-interacting protein 2; rab-3-interacting protein 2; rab;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • E.coli
  • HEK293
  • Mammalian Cell
  • GST
  • His
  • His (Fc)
  • Avi
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human RIMS1-2307H Recombinant Human RIMS1, GST-tagged E.coli GST 912-1028aa
Mouse RIMS1-14230M Recombinant Mouse RIMS1 Protein Mammalian Cell His
Mouse RIMS1-7608M-B Recombinant Mouse RIMS1 Protein Pre-coupled Magnetic Beads HEK293
Mouse RIMS1-7608M Recombinant Mouse RIMS1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat RIMS1-5047R Recombinant Rat RIMS1 Protein Mammalian Cell His
Rat RIMS1-4706R Recombinant Rat RIMS1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat RIMS1-4706R-B Recombinant Rat RIMS1 Protein Pre-coupled Magnetic Beads HEK293
  • Involved Pathway
  • Protein Function
  • Interacting Protein

RIMS1 involved in several pathways and played different roles in them. We selected most pathways RIMS1 participated on our site, such as Synaptic vesicle cycle, Retrograde endocannabinoid signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with RIMS1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Synaptic vesicle cycleATP6V0E2;NSF;ATP6V0E1;CPLX4;ATP6V1E1;ATP6V0D2;UNC13A;ATP6V0D1;ATP6V1B1
Retrograde endocannabinoid signalingGNG7;PLCB1;GNAO1;PRKCA;GRIA2;PLCB3;SLC17A6;GABRQ;GRIA4

RIMS1 has several biochemical functions, for example, GTPase regulator activity, Rab GTPase binding, ion channel binding. Some of the functions are cooperated with other proteins, some of the functions could acted by RIMS1 itself. We selected most functions RIMS1 had, and list some proteins which have the same functions with RIMS1. You can find most of the proteins on our site.

Function Related Protein
GTPase regulator activityRGS14A;RUNDC3A;RHPN1;GPSM2L;GPSM1B;RGS12B;KRIT1;WAS;TSC1
Rab GTPase bindingLLGL1;HACE1;ACAP2;RUSC2;MYO5B;EVI5L;RAB11FIP4A;TBC1D7;SGSM3
ion channel bindingRNF207;TRPC1;KCNC1;FKBP1B;ABCC9;FXYD1;RIMS1;CALM1;YWHAQ
metal ion bindingPHLPP2;MARCH11;CPXCR1;ZNF280B;ZBTB9;SMAD9;DPYDB;MTHFS;AGAP1
poly(A) RNA bindingBOP1;PURB;SRP54B;SUMO2;GRN;TPT1;CPSF7;PARN;CIRH1A
protein bindingNDUFAF1;UBASH3B;FKBP8;DNER;PKD2L1;TTC25;ERCC1;CEBPB;HOXB9

RIMS1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RIMS1 here. Most of them are supplied by our site. Hope this information will be useful for your research of RIMS1.

ABL1; FYN; NCK1; GRB2; SMAD2; LRRK1; pi3p

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