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RLIM

  • Official Full Name

    ring finger protein, LIM domain interacting

  • Overview

    The protein encoded by this gene is a RING-H2 zinc finger protein. It has been shown to be an E3 ubiquitin protein ligase that targets LIM domain binding 1 (LDB1/CLIM), and causes proteasome-dependent degradation of LDB1. This protein and LDB1 are co-repressors of LHX1/LIM-1, a homeodomain transcription factor. Multiple alternatively spliced variants, encoding the same protein, have been identified.
  • Synonyms

    RNF12; FLJ25923; FLJ41093; FLJ42887; FLJ45986; MGC15161; NY-REN-43; DKFZp686N06224; E3 ubiquitin-protein ligase RLIM; R-LIM; OTTHUMP00000023574; OTTHUMP00000023575; ring finger protein 12; E3 ubiquitin-protein ligase RNF12; renal carcinoma antigen NY-REN-43; RING finger LIM domain-binding protein; ring zinc finger protein NY-REN-43antigen; LIM domain-interacting RING finger protein; ring zinc finger LIM domain binding protein; RLIM; ring finger protein LIM domain interacting;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rhesus Macaque
  • E.coli
  • HEK293
  • Mammalian Cell
  • GST
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human RLIM-2318H Recombinant Human RLIM, GST-tagged E.coli GST 276-350aa
Human RLIM-498H Recombinant Human RLIM Protein, His-tagged E.coli His
Human RLIM-1517HCL Recombinant Human RLIM cell lysate N/A
Mouse RLIM-14254M Recombinant Mouse RLIM Protein Mammalian Cell His
Mouse RLIM-7622M Recombinant Mouse RLIM Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse RLIM-7622M-B Recombinant Mouse RLIM Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque RLIM-3903R Recombinant Rhesus monkey RLIM Protein, His-tagged Mammalian Cell His
Rhesus Macaque RLIM-3720R Recombinant Rhesus Macaque RLIM Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque RLIM-3720R-B Recombinant Rhesus Macaque RLIM Protein Pre-coupled Magnetic Beads HEK293
Chicken RLIM-6391C Recombinant Chicken RLIM Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

RLIM involved in several pathways and played different roles in them. We selected most pathways RLIM participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with RLIM were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

RLIM has several biochemical functions, for example, ligase activity, transcription corepressor activity, ubiquitin protein ligase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by RLIM itself. We selected most functions RLIM had, and list some proteins which have the same functions with RLIM. You can find most of the proteins on our site.

Function Related Protein
ligase activityRNF133;RNF14;HECW1B;ATG10;CDC34B;TRAF7;UBR7;HECW2;CDC34A
transcription corepressor activitySETD8;ZHX1;RARA;APEX1;HDAC9;NR2F2;NR0B2;NSD1;ENO1
ubiquitin protein ligase activityUBE2G1B;UBE2N;UBE2NA;MED1;WWP1;HERC2;HERC5;MED20;SMURF1
ubiquitin-protein transferase activityRAG1;RNF31;RBBP6;FBXL14;MALT1;UBE2O;FLJ11011L;BRCA1;UBE2G2
zinc ion bindingZDHHC15B;ABLIM1B;CD4;ZBTB32;RNF11;NRAP;RUNX1;HIF1AN;ZDHHC11

RLIM has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RLIM here. Most of them are supplied by our site. Hope this information will be useful for your research of RLIM.

LDB2; UBE2O; UBE2D1; UBE2E1; UBE2D3; RPS14; UBE2D2; SNX17; LNX2; UBE2E2; UBE2D4; UBXN1; TOLLIP; LMO2; LDB1

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