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RNF19B

Official Full Name

ring finger protein 19B
Overview

IBRDC3 is a cytolysis-associated transmembrane protein expressed in natural killer (NK) cells and T lymphocytes;following cytokine stimulation (Kozlowski et al., 1999 (PubMed 10438909)).
Synonyms

RNF19B; ring finger protein 19B; IBR domain containing 3 , IBRDC3; E3 ubiquitin-protein ligase RNF19B; FLJ90005; IBR domain containing 3; IBR domain-containing protein 3; IBRDC3; Natural killer lytic-associated molecule; NKLAM; RN19B_HUMAN;

Type

Cell & Tissue Lysates
Recombinant Proteins

Species

Danio rerio (Zebrafish) (Brachydanio rerio)
Homo sapiens (Human)
Human
Mus musculus (Mouse)
Xenopus laevis (African clawed frog)
Zebrafish

Source

E.coli expression system
HEK293
Mammalian Cell

Tag

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	RNF19B-546HCL	Recombinant Human RNF19B lysate	HEK293	N/A		Inquiry
Danio rerio (Zebrafish) (Brachydanio rerio)	RFL31299DF	Recombinant Full Length Danio Rerio E3 Ubiquitin-Protein Ligase Rnf19B(Rnf19B) Protein, His-Tagged	E.coli expression system	His	Full Length (1-701)	Inquiry
Homo sapiens (Human)	RFL25743HF	Recombinant Full Length Human E3 Ubiquitin-Protein Ligase Rnf19B(Rnf19B) Protein, His-Tagged	E.coli expression system	His	Full Length (1-732)	Inquiry
Mus musculus (Mouse)	RFL6677MF	Recombinant Full Length Mouse E3 Ubiquitin-Protein Ligase Rnf19B(Rnf19B) Protein, His-Tagged	E.coli expression system	His	Full Length (1-732)	Inquiry
Xenopus laevis (African clawed frog)	RFL4243XF	Recombinant Full Length Xenopus Laevis E3 Ubiquitin-Protein Ligase Rnf19B(Rnf19B) Protein, His-Tagged	E.coli expression system	His	Full Length (1-687)	Inquiry
Zebrafish	RNF19B-7968Z	Recombinant Zebrafish RNF19B	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein

RNF19B involved in several pathways and played different roles in them. We selected most pathways RNF19B participated on our site, such as Adaptive Immune System, Antigen processing: Ubiquitination &amp, Proteasome degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with RNF19B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Adaptive Immune System	CD160;KIF5B;UBR2;DYNC1LI2;DZIP3;WSB1;KIF4A;RNF220;CRTAM
Antigen processing: Ubiquitination &amp	RNF182;ASB10;STUB1;UBE2E3;ASB9;RNF6;ASB14;ATG7;PJA1
Proteasome degradation	UBE2V1;UBE2F;SPSB1;VPRBP;MKRN1;ASB11;UBR2;UBE2V2;RNF25
Class I MHC mediated antigen processing &amp	WSB1;RNF41;TRIM11;LTN1;UBE2F;RNF25;RBCK1;ASB2;UBE2U
presentation	TRAF7;RNF123;FBXO27;KLHL21;VPRBP;HECTD3;ASB6;TRIM9;UBE2E3
Immune System	RAPGEF4;CXADR;RNF6;TRAF7;RNF123;OSBPL1A;KIF11;CFHL1;IFIT14

RNF19B has several biochemical functions, for example, ligase activity, protein binding, ubiquitin conjugating enzyme binding. Some of the functions are cooperated with other proteins, some of the functions could acted by RNF19B itself. We selected most functions RNF19B had, and list some proteins which have the same functions with RNF19B. You can find most of the proteins on our site.

Function	Related Protein
ligase activity	SIAH1;RNF38;PJA2;HECTD1;MIB2;CDC34B;CBX4;SMURF1;MDM2
protein binding	PEX11G;KIF7;EFCAB4A;TIFA;PRR13;CEP170L;EMX2;ARMC7;NTF3
ubiquitin conjugating enzyme binding	RNF144B;DCUN1D2A;ZMYM2;ANKIB1A;MARCH6;ARIH2;RNF217;GRIK2;RNF144AB
ubiquitin protein ligase activity	UBE2V2;MARCH1;RNF19B;PELI1;SMURF1;RNF217;UHRF2;TRIM71;ITCH
zinc ion binding	ZFP326;SP110;RNF122;ZDHHC5A;RBM4;PML;TRIM35-21;LMO4B;CTCF

RNF19B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RNF19B here. Most of them are supplied by our site. Hope this information will be useful for your research of RNF19B.

UCKL1; UBE2L6; UBE2L3; HSP90AB1; PPP1CC