RNF19B
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Official Full Name
ring finger protein 19B -
Overview
IBRDC3 is a cytolysis-associated transmembrane protein expressed in natural killer (NK) cells and T lymphocytes;following cytokine stimulation (Kozlowski et al., 1999 (PubMed 10438909)). -
Synonyms
RNF19B;ring finger protein 19B;IBR domain containing 3 , IBRDC3;E3 ubiquitin-protein ligase RNF19B;FLJ90005;IBR domain containing 3;IBR domain-containing protein 3;IBRDC3;Natural killer lytic-associated molecule;NKLAM;RN19B_HUMAN
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| RNF19B-7968Z | Recombinant Zebrafish RNF19B | Mammalian Cells | Zebrafish | His |
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| RNF19B-546HCL | Recombinant Human RNF19B lysate | HEK293 | Human | Non |
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| RFL25743HF | Recombinant Full Length Human E3 Ubiquitin-Protein Ligase Rnf19B(Rnf19B) Protein, His-Tagged | E.coli | Human | His | Full L. Full Length (1-732) |
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| RFL31299DF | Recombinant Full Length Danio Rerio E3 Ubiquitin-Protein Ligase Rnf19B(Rnf19B) Protein, His-Tagged | E.coli | zebrafish | His | Full L. Full Length (1-701) |
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| RFL4243XF | Recombinant Full Length Xenopus Laevis E3 Ubiquitin-Protein Ligase Rnf19B(Rnf19B) Protein, His-Tagged | E.coli | Xenopus laevis | His | Full L. Full Length (1-687) |
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| RFL6677MF | Recombinant Full Length Mouse E3 Ubiquitin-Protein Ligase Rnf19B(Rnf19B) Protein, His-Tagged | E.coli | Mus musculus | His | Full L. Full Length (1-732) |
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Involved Pathway
RNF19B involved in several pathways and played different roles in them. We selected most pathways RNF19B participated on our site, such as Adaptive Immune System,Antigen processing: Ubiquitination &,Proteasome degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with RNF19B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Immune System | IFI35,NLRP4C,HUWE1,AP1S3A,FBXO27,SIGLEC6,SPSB1,MB21D1,RNF135,CSH1 |
| Proteasome degradation | UFL1,KLHL20,TRIM63,NPEPPS,ASB13,ASB8,SPSB4,HECTD3,FBXO44,WSB1 |
| presentation | RNF34,NPEPPS,UBR1,TPP2,SPSB2,SPSB4,UBE2V1,RNF182,UBE2U,TRIM9 |
| Adaptive Immune System | CD300LB,CTLA4,CD200R1,ASB8,MICA,GRAP2A,CDKN1B,CD200R2,MOV10,STIM1B |
| Class I MHC mediated antigen processing & | SPSB1,DZIP3,ASB13,UBE2F,TRIM63,UBE2V1,BLMH,RNF6,RBCK1,TPP2 |
| Antigen processing: Ubiquitination & | FBXO27,TRIM9,UBR1,ATG7,RNF111,ASB18,RNF182,UFL1,ASB7,STUB1 |
Protein Function
RNF19B has several biochemical functions, for example, ligase activity,protein binding,ubiquitin conjugating enzyme binding. Some of the functions are cooperated with other proteins, some of the functions could acted by RNF19B itself. We selected most functions RNF19B had, and list some proteins which have the same functions with RNF19B. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| zinc ion binding | MYLIP,MMP23B,RNF5,ZFAND5,TRIM47,ZDHHC6,ZYX,SIRT5,CRYZ,MMP1A |
| ubiquitin conjugating enzyme binding | ARIH1,DCUN1D1,ARIH1L,RNF144A,ZMYM2,ARIH2,DCUN1D2A,DCUN1D4,TOLLIP,RNF14 |
| ligase activity | TRIM58,TRIM32,HERC2,LIPT2,TRIM71,CBLB,UFL1,TTLL2,TTLL11,CCNB1IP1 |
| ubiquitin protein ligase activity | RNF19A,RNF144B,UBE2H,HECW1B,MED21,HECW2,STUB1,CMTM2A,ASB4,CDC34A |
| protein binding | SLC25A46,SERPINA5,GSE1,PAN2,RYR1,CKS1B,SUGP1,UHRF2,MAP3K7,CASP7 |
Interacting Protein
RNF19B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RNF19B here. Most of them are supplied by our site. Hope this information will be useful for your research of RNF19B.
UCKL1;UBE2L6;UBE2L3;HSP90AB1;PPP1CC
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