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RPS18

Official Full Name

ribosomal protein S18
Overview

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S13P family of ribosomal proteins. It is located in the cytoplasm. The gene product of the E. coli ortholog (ribosomal protein S13) is involved in the binding of fMet-tRNA, and thus, in the initiation of translation. This gene is an ortholog of mouse Ke3. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.
Synonyms

RPS18; ribosomal protein S18; D6S218E; 40S ribosomal protein S18; HKE3; KE 3; KE3; S18; Rhabdomyosarcoma antigen MU-RMS-40.21; OTTHUMP00000029059; KE-3;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse
Rat
Zebrafish

Source

E.coli
HEK293
Mammalian Cell

Tag

Species	Cat.#	Product name	Source (Host)	Tag	Price
Human	RPS18-297H	Recombinant Human ribosomal protein S18, His-tagged	E.coli	His	Inquiry
Human	RPS18-2170HCL	Recombinant Human RPS18 293 Cell Lysate	HEK293	Non	Inquiry
Mouse	RPS18-14474M	Recombinant Mouse RPS18 Protein	Mammalian Cell	His	Inquiry
Mouse	RPS18-7774M	Recombinant Mouse RPS18 Protein, His (Fc)-Avi-tagged	HEK293	His&Fc&Avi	Inquiry
Mouse	RPS18-7774M-B	Recombinant Mouse RPS18 Protein Pre-coupled Magnetic Beads	HEK293		Inquiry
Rat	RPS18-5155R	Recombinant Rat RPS18 Protein	Mammalian Cell	His	Inquiry
Rat	RPS18-4814R	Recombinant Rat RPS18 Protein, His (Fc)-Avi-tagged	HEK293	His&Fc&Avi	Inquiry
Rat	RPS18-4814R-B	Recombinant Rat RPS18 Protein Pre-coupled Magnetic Beads	HEK293		Inquiry
Zebrafish	RPS18-9508Z	Recombinant Zebrafish RPS18	Mammalian Cell	His	Inquiry

Involved Pathway
Protein Function
Interacting Protein
Other Resource

RPS18 involved in several pathways and played different roles in them. We selected most pathways RPS18 participated on our site, such as Ribosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with RPS18 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Ribosome	RPL8;MRPL33;RPL4;FAUA;MRPL35;RPS4Y2;RPS6;MRPL30;MRPL34

RPS18 has several biochemical functions, for example, poly(A) RNA binding, protein binding, rRNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by RPS18 itself. We selected most functions RPS18 had, and list some proteins which have the same functions with RPS18. You can find most of the proteins on our site.

Function	Related Protein
poly(A) RNA binding	RC3H2;TRIM25;RPS14;LUZP4;SNW1;MRPL28;MAGOH2;CISD2;ZNF622
protein binding	FYN;PIK3R3;KCNIP1;HIC1;TPP2;UBE2D1;TPD52L2;CD1A;RAD51L3
rRNA binding	FASTKD5;PPAN;MRPL11;DDX28;MRPL16;TLR13;ERI1;ERAL1;MTERFD2
structural constituent of ribosome	MRPS14;RPL18A;RPS3;MRPS18B;MRP63;RPL36AL;RPL8;RPS17;SLC25A24L

RPS18 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RPS18 here. Most of them are supplied by our site. Hope this information will be useful for your research of RPS18.

ESR2; ESR1; CSNK2A1; LRRK2; TNF; TNFRSF1B; ACTB; NFKB2; MAP3K14; TBK1; ERG; midostaurin; 2_aha_camp; 8-aha-camp

Research Area

Rugjee, KN; Chaudhury, SR; et al. Fluorescent protein tagging confirms the presence of ribosomal proteins at Drosophila polytene chromosomes. PEERJ 1:-(2013).