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RSPO4

  • Official Full Name

    R-spondin family, member 4

  • Synonyms

    A730099F22; A930029K19Rik;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Zebrafish
  • E.coli
  • HEK293
  • Mammalian Cell
  • GST
  • His
  • His (Fc)
  • Avi
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human RSPO4-1001H Recombinant Human RSPO4 Mammalian Cell His
Human RSPO4-3715H Recombinant Human RSPO4 protein, His-tagged E.coli His 163-234 aa
Human RSPO4-301500H Recombinant Human RSPO4 protein, GST-tagged E.coli GST Leu163-Pro234
Human RSPO4-4014H-B Recombinant Human RSPO4 Protein Pre-coupled Magnetic Beads HEK293
Human RSPO4-4014H Recombinant Human RSPO4 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Zebrafish RSPO4-8401Z Recombinant Zebrafish RSPO4 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • RSPO4 Related Articles
  • RSPO4 Related Research Area
  • RSPO4 Related Signal Pathway

RSPO4 involved in several pathways and played different roles in them. We selected most pathways RSPO4 participated on our site, such as Regulation of FZD by ubiquitination, Signal Transduction, Signaling by Wnt, which may be useful for your reference. Also, other proteins which involved in the same pathway with RSPO4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Regulation of FZD by ubiquitinationLGR4;ZNRF3;FMNL3;RSPO1;LGR6;RNF43;RSPO3;RSPO2;RSPO4
Signal TransductionLGR6;LGR4;RDH7;RGS11;CCRL2;APOC2;RLN1;DEPDC7;FFAR3
Signaling by WntGPR177;TNKS;TNKS2;FMNL3;RSPO4;RSPO2;WLS;RBBP5;RYK
TCF dependent signaling in response to WNTWIF1;ASH2L;TLE3B;KREMEN1;PYGO2;RBBP5;SOX6;USP34;PYGO1

RSPO4 has several biochemical functions, for example, G-protein coupled receptor binding, heparin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by RSPO4 itself. We selected most functions RSPO4 had, and list some proteins which have the same functions with RSPO4. You can find most of the proteins on our site.

Function Related Protein
G-protein coupled receptor bindingPACRG;PROK1;HSPA1A;UTS2D;USP33;PROK2;PSAPL1;GNA14;PICK1
heparin bindingNRP1;FGF14;APOB;COL5A1;CHRD;CCL23;PDCD5;RSPO1;SLIT1B

RSPO4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RSPO4 here. Most of them are supplied by our site. Hope this information will be useful for your research of RSPO4.

Xu, JG; Huang, CF; et al. Crystal Structure of LGR4-Rspo1 Complex INSIGHTS INTO THE DIVERGENT MECHANISMS OF LIGAND RECOGNITION BY LEUCINE-RICH REPEAT G-PROTEIN-COUPLED RECEPTORS (LGRs). JOURNAL OF BIOLOGICAL CHEMISTRY 290:2455-2465(2015).
Carmon, KS; Gong, X; et al. RSPO-LGR4 functions via IQGAP1 to potentiate Wnt signaling. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 111:E1221-E1229(2014).
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