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RXFP4

  • Official Full Name

    relaxin/insulin-like family peptide receptor 4

  • Overview

    GPR100 is a member of the rhodopsin family of G protein-coupled receptors (GPRs) (Fredriksson et al., 2003 (PubMed;14623098)).
  • Synonyms

    RXFP4; relaxin/insulin-like family peptide receptor 4; G protein coupled receptor 100 , GPR100, relaxin 3 receptor 2 , relaxin family peptide receptor 4 , RLN3R2; relaxin-3 receptor 2; GPCR142; RXFPR4; G protein coupled receptor 100; Relaxin 3 receptor 2; Relaxin family peptide receptor 4; RLN3R2; RLN3 receptor 2; G protein-coupled receptor 100; G-protein coupled receptor 100; G-protein coupled receptor GPCR142; insulin-like peptide INSL5 receptor; GPR100;
Species Cat.# Product name Source (Host) Tag Protein Length Price
Homo sapiens (Human) RFL20762HF Recombinant Full Length Human Relaxin-3 Receptor 2(Rxfp4) Protein, His-Tagged E.coli expression system His Full Length (1-374)
Mus musculus (Mouse) RFL13804MF Recombinant Full Length Mouse Relaxin-3 Receptor 2(Rxfp4) Protein, His-Tagged E.coli expression system His Full Length (1-414)
Kit-0998 Cell Invasion Assay Kit (Collagen I), 8 μm N/A
Kit-1517 RXFP4 CHO-K1 β-Arrestin GPCR Assay Kit N/A
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • RXFP4 Related Articles

RXFP4 involved in several pathways and played different roles in them. We selected most pathways RXFP4 participated on our site, such as Neuroactive ligand-receptor interaction, which may be useful for your reference. Also, other proteins which involved in the same pathway with RXFP4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Neuroactive ligand-receptor interactionGABRB3;LPAR6;HCRTR2;GRM2;TRHR;P2RX6;F2RL1.1;P2RY10;TAAR8C

RXFP4 has several biochemical functions, for example, G-protein coupled peptide receptor activity, angiotensin type II receptor activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by RXFP4 itself. We selected most functions RXFP4 had, and list some proteins which have the same functions with RXFP4. You can find most of the proteins on our site.

Function Related Protein
G-protein coupled peptide receptor activityNPR1;LTB4R;TSHR;GPR37;MC1R;CYSLTR1;GPR37L1;LTB4R2;CYSLTR2
angiotensin type II receptor activityCXCR3.2;AGTR2;RXFP3.2B;AGTR1A;APLNRA;AGTR1;RXFP4;APLNRB;AGTR1B
protein bindingKRT17;ITGB1BP2;PKD2;MED24;PTCH1;C14orf135;CC2D1B;SRI;DEDD

RXFP4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RXFP4 here. Most of them are supplied by our site. Hope this information will be useful for your research of RXFP4.

RLN3

Perkins, SD; Key, CN; et al. Residual feed intake studies in Angus-sired cattle reveal a potential role for hypothalamic gene expression in regulating feed efficiency. JOURNAL OF ANIMAL SCIENCE 92:549-560(2014).
Munro, J; Skrobot, O; et al. Relaxin polymorphisms associated with metabolic disturbance in patients treated with antipsychotics. JOURNAL OF PSYCHOPHARMACOLOGY 26:374-379(2012).
Hanna, CB; Yao, S; et al. Expression of insulin-like 3 (INSL3) and differential splicing of its receptor in the ovary of rhesus macaques. REPRODUCTIVE BIOLOGY AND ENDOCRINOLOGY 8:-(2010).
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