• Official Full Name

    sphingosine-1-phosphate receptor 4

  • Overview

    This gene is a member of the endothelial differentiation, G-protein-coupled (EDG)) receptor gene family. EDG receptors bind lysophospholipids or lysosphingolipids as ligands, and are involved in cell signalling in many different cell types. This EDG receptor gene is intronless and is specifically expressed in the lymphoid tissue.
  • Synonyms

    S1PR4; sphingosine-1-phosphate receptor 4; EDG6, endothelial differentiation, G protein coupled receptor 6 , endothelial differentiation, lysophosphatidic acid G protein coupled receptor, 6; sphingosine 1-phosphate receptor 4; Endothelial differentiationlysophosphatidic acid G protein coupled receptor 6; Endothelial differentiation G protein coupled receptor 6; Endothelial differentiation G-protein coupled receptor 6; Endothelial differentiation gene 6; LPC1; Lysophospholipid receptor C1; MGC129298; Putative G protein coupled receptor; S1P receptor 4; S1P receptor Edg-6; S1P receptor Edg6; S1P4; S1PR4_HUMAN; SLP4; Sphingosine 1 phosphate receptor 4; Sphingosine 1 phosphate receptor Edg6; Sphingosine 1-phosphate receptor Edg-6; endothelial differentiation, G protein coupled receptor 6; endothelial differentiation, G-protein-coupled receptor 6; endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 6; EDG6;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Homo sapiens (Human)
  • Human
  • Mouse
  • Rhesus Macaque
  • Zebrafish
  • E.coli expression system
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human S1PR4-4042H Recombinant Human S1PR4 Protein, GST-tagged Wheat Germ GST
Human S1PR4-2083HCL Recombinant Human S1PR4 293 Cell Lysate HEK293 N/A
Human S1PR4-4742HF Recombinant Full Length Human S1PR4 Protein, GST-tagged In Vitro Cell Free System GST 384 amino acids
Mouse S1PR4-14631M Recombinant Mouse S1PR4 Protein Mammalian Cell His
Mouse S1PR4-7874M-B Recombinant Mouse S1PR4 Protein Pre-coupled Magnetic Beads HEK293
Mouse S1PR4-7874M Recombinant Mouse S1PR4 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Homo sapiens (Human) RFL7620HF Recombinant Full Length Human Sphingosine 1-Phosphate Receptor 4(S1Pr4) Protein, His-Tagged E.coli expression system His Full Length (1-384)
Rhesus Macaque S1PR4-4067R Recombinant Rhesus monkey S1PR4 Protein, His-tagged Mammalian Cell His
Rhesus Macaque S1PR4-3884R-B Recombinant Rhesus Macaque S1PR4 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque S1PR4-3884R Recombinant Rhesus Macaque S1PR4 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Zebrafish S1PR4-6557Z Recombinant Zebrafish S1PR4 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Other Resource

S1PR4 involved in several pathways and played different roles in them. We selected most pathways S1PR4 participated on our site, such as FoxO signaling pathway, Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction, which may be useful for your reference. Also, other proteins which involved in the same pathway with S1PR4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
FoxO signaling pathwayKLF2;ATM;TGFB2;KLF2B;G6PC3;SMAD4;CDKN2B;PIK3R5;PLK4
Sphingolipid signaling pathwayKRAS;ABCC1;MAPK11;S1PR5;PLD2;PPP2R5B;TRP53;LOC100328615;MS4A2
Neuroactive ligand-receptor interactionP2RX8;TAAR14H;MTNR1AA;MTNR1B;GHRHR;DRD4B;TAAR13B;PTGER4;TAAR14J

S1PR4 has several biochemical functions, for example, G-protein coupled receptor activity, lipid binding, sphingosine-1-phosphate receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by S1PR4 itself. We selected most functions S1PR4 had, and list some proteins which have the same functions with S1PR4. You can find most of the proteins on our site.

Function Related Protein
G-protein coupled receptor activityOLFR498;OR51D1;TAAR6;FZD8;Fzd4;CXCR4B;TAAR14G;GPR6;OR2AP1
sphingosine-1-phosphate receptor activitySPHK2;S1PR5B;S1PR1;GPR6;SPHK1;S1PR5A;S1PR2;S1PR3;S1PR3A

S1PR4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with S1PR4 here. Most of them are supplied by our site. Hope this information will be useful for your research of S1PR4.

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