SDCCAG8
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Official Full Name
serologically defined colon cancer antigen 8 -
Overview
This gene encodes a centrosome associated protein. This protein may be involved in organizing the centrosome during interphase and mitosis. Mutations in this gene are associated with retinal-renal ciliopathy. -
Synonyms
SDCCAG8;serologically defined colon cancer antigen 8;BBS16;CCCAP;NPHP10;NY CO 8;SLSN7;Antigen NY CO 8;Centrosomal colon cancer autoantigen protein;HSPC085;NPHP10 gene;NY-CO-8;Serologically defined colon cancer antigen 8 homolog;SLSN7 gene;antigen NY-CO-8;hCCCAP
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| SDCCAG8-2552H | Recombinant Human SDCCAG8, GST-tagged | E.coli | Human | GST | 1-360aa | |
| SDCCAG8-14796M | Recombinant Mouse SDCCAG8 Protein | Mammalian Cells | Mouse | His |
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| SDCCAG8-30297TH | Recombinant Human SDCCAG8, His-tagged | E.coli | Human | His | 51-380 a.a. |
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| SDCCAG8-1576HCL | Recombinant Human SDCCAG8 cell lysate | Human | Non |
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| SDCCAG8-7962M | Recombinant Mouse SDCCAG8 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | Avi&Fc&His |
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| SDCCAG8-7962M-B | Recombinant Mouse SDCCAG8 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
SDCCAG8 involved in several pathways and played different roles in them. We selected most pathways SDCCAG8 participated on our site, such as Anchoring of the basal body to the plasma membrane,Assembly of the primary cilium,Cell Cycle, which may be useful for your reference. Also, other proteins which involved in the same pathway with SDCCAG8 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Assembly of the primary cilium | FLR,EXOC1,IFT43,CLASP1A,MAPRE1,PKD1,DYNLRB1,CCT3,BBS4,MAPRE1B |
| Loss of proteins required for interphase microtubule organizationfrom the centrosome | CEP290,NINL,MAPRE1,CEP164,CEP70,CEP78,MAPRE1B,TUBG1,CEP152,HAUS2 |
| Cell cycle | DYRK1A,BUB3,PDS5B,SMAD2,CDT1,CDK1,ESCO2,MAD2L2,KIF2C,LIN52 |
| Loss of Nlp from mitotic centrosomes | CEP76,TSGA14,DCTN1A,CEP164,CEP57,CLASP1A,MAPRE1B,CEP63,CEP152,MAPRE1 |
| Centrosome maturation | TUBGCP5,TUBG2,HAUS2,ODF2B,DCTN2,DCTN1A,TUBGCP4,CEP135,CSNK1E,CEP63 |
| Anchoring of the basal body to the plasma membrane | CEP70,TMEM216,CSNK1D,RPGRIP1L,CDK5RAP2,CEP97,DCTN1A,RAB3IP,CEP76,SCLT1 |
| G2/M Transition | ODF2,NDE1,TUBGCP4,MAPRE1A,TUBGCP5,NEDD1,CEP135,PCM1,PLK4,DCTN1A |
| Cell Cycle, Mitotic | MIS12,PLK4,SKA2,NUPL2,NDEL1,NIPBLA,GINS3,CSNK2A1,SETB,E2F2 |
Protein Function
SDCCAG8 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SDCCAG8 itself. We selected most functions SDCCAG8 had, and list some proteins which have the same functions with SDCCAG8. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | CD1B,DRAP1,SETDB1,Mill2,NKX3,COMMD3,EMILIN1,PLD3,UHMK1,NIPBL |
Interacting Protein
SDCCAG8 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SDCCAG8 here. Most of them are supplied by our site. Hope this information will be useful for your research of SDCCAG8.
gag;TRAF6;p29991-pro_0000037946;yhdL;TSC1;q99ib8-pro_0000045599;q9wmx2-pro_0000037548;Rab7a;Ube2k;SRSF2;ZNF423;CEP164
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References
- Scanlan, MJ; Welt, S; et al. Cancer-related serological recognition of human colon cancer: Identification of potential diagnostic and immunotherapeutic targets. CANCER RESEARCH 62:4041-4047(2002).
