|Official Full Name||sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E|
|Background||Semaphorins are a large family of conserved secreted and membrane associated proteins which possess a semaphorin (Sema) domain and a PSI domain (found in plexins, semaphorins and integrins) in the N-terminal extracellular portion. Based on sequence and structural similarities, semaphorins are put into eight classes: invertebrates contain classes 1 and 2, viruses have class V, and vertebrates contain classes 3-7. Semaphorins serve as axon guidance ligands via multimeric receptor complexes, some (if not all) containing plexin proteins. This gene encodes a class 4 semaphorin. This gene encodes a class 3 semaphorin. Multiple transcript variants encoding different isoforms have been found for this gene.|
|Synonyms||SEMA3E; sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E; SEMAH; semaphorin-3E; coll 5; KIAA0331; M sema H; M SemaK; coll-5; M-SEMAH; M-SemaK|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
SEMA3E involved in several pathways and played different roles in them. We selected most pathways SEMA3E participated on our site, such as Axon guidance, which may be useful for your reference. Also, other proteins which involved in the same pathway with SEMA3E were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Axon guidance||GNAI3; HRAS; PAK4; ACTR2; CSNK2B; FYN; CSF2RB; SEMA7A; AP2A2; EFNA4|
SEMA3E has several biochemical functions, for example, chemorepellent activity, neuropilin binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SEMA3E itself. We selected most functions SEMA3E had, and list some proteins which have the same functions with SEMA3E. You can find most of the proteins on our site.
|chemorepellent activity||SEMA6A; SEMA3A; SEMA4D; EPHA7; FLRT3; SEMA5A; SEMA4B; SEMA4E; SEMA5B; SEMA3G|
|neuropilin binding||SEMA3AB; SEMA3C; SEMA3A; SEMA4E; SEMA3H; SEMA7A; SEMA3AA; SEMA3GA; SEMA3FA; SEMA3E|
|protein binding||RAB6A; SLC25A10; BBS9; NR3C2; MED10; TPT1; BIN2; NFS1; CUTC; DTNBP1|
|semaphorin receptor binding||SEMA3G; SEMA6DL; SEMA3GA; SEMA3E; SEMA3A; SEMA3AA; SEMA3GB; SEMA4B; SEMA4A; SEMA3AB|
SEMA3E has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SEMA3E here. Most of them are supplied by our site. Hope this information will be useful for your research of SEMA3E.