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SEMA4B

  • Official Full Name

    sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B

  • Overview

    Semaphorin-4B is a protein that in humans is encoded by the SEMA4B gene.
  • Synonyms

    SEMA4B; sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B; SEMAC; semaphorin-4B; KIAA1745; MGC131831; SemC; Sema domain immunoglobulin domain (Ig) transmembrane domain (TM) and short cytoplasmic domain (semaphorin) 4B; Sema domain immunoglobulin domain (Ig) transmembrane domain (TM) and short cytoplasmic domain 4B; Semaphorin 4B; sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, 4B;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • E.coli
  • HEK293
  • HEK293T
  • Mammalian Cell
  • Mammalian cells
  • C
  • Fc
  • His
  • Fc|His
  • GST
  • His (Fc)
  • Avi
  • His|GST
  • Myc
  • DDK
  • Myc|DDK
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human SEMA4B-2575H Recombinant Human SEMA4B, GST-tagged E.coli GST 78aa-330aa
Human SEMA4B-352H Recombinant Human SEMA4B Protein, Fc/His-tagged HEK293 Fc/His
Human SEMA4B-1540H Recombinant Human SEMA4B protein, His-tagged E.coli His Leu192~Thr367
Human SEMA4B-3798H Recombinant Human SEMA4B Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human SEMA4B-1541H Recombinant Human SEMA4B protein, His & GST-tagged E.coli His/GST Gln644~Val832 (Accession # Q9NPR2)
Human SEMA4B-595H Recombinant Human SEMA4B Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human SEMA4B-2773H Recombinant Human SEMA4B Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human SEMA4B-5548H Recombinant Human SEMA4B Protein (Gln649-Val837), N-GST tagged E.coli N-GST Gln649-Val837
Human SEMA4B-5549H Recombinant Human SEMA4B Protein (Leu39-Glu712), C-Fc and His tagged Mammalian cells C-Fc and His Leu39-Glu712
Mouse SEMA4B-14867M Recombinant Mouse SEMA4B Protein Mammalian Cell His
Mouse Sema4b-1542M Recombinant Mouse Sema4b protein, His-tagged E.coli His Leu31~Pro240 (Accession # Q62179)
Mouse SEMA4B-8006M Recombinant Mouse SEMA4B Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse SEMA4B-8006M-B Recombinant Mouse SEMA4B Protein Pre-coupled Magnetic Beads HEK293
Mouse Sema4b-5759M Recombinant Mouse Sema4b Protein, Myc/DDK-tagged HEK293T Myc/DDK
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • SEMA4B Related Articles
  • SEMA4B Related Research Area

SEMA4B involved in several pathways and played different roles in them. We selected most pathways SEMA4B participated on our site, such as Axon guidance, which may be useful for your reference. Also, other proteins which involved in the same pathway with SEMA4B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Axon guidanceEPHA10;GPC1B;KIF4;PLXNA1;MAPK1;GNAI2;JAK1;Unc5b;SLIT2

SEMA4B has several biochemical functions, for example, chemorepellent activity, NOT neuropilin binding, semaphorin receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SEMA4B itself. We selected most functions SEMA4B had, and list some proteins which have the same functions with SEMA4B. You can find most of the proteins on our site.

Function Related Protein
chemorepellent activityFLRT3;SEMA3AA;SEMA6B;SEMA4C;SEMA6E;SEMA4BA;SEMA3H;SEMA3GA;SEMA4E
NOT neuropilin bindingSEMA4BA;SEMA4D;SEMA4B;SEMA4C;SEMA4A
semaphorin receptor bindingSema3f;SEMA3G;SEMA3FA;SH3BGRL3;SEMA5B;SEMA4D;SEMA4A;SEMA6DL;SEMA3D

SEMA4B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SEMA4B here. Most of them are supplied by our site. Hope this information will be useful for your research of SEMA4B.

Jian, H; Zhao, Y; et al. SEMA4b inhibits MMP9 to prevent metastasis of non-small cell lung cancer. TUMOR BIOLOGY 35:11051-11056(2014).
Jian, H; Liu, B; et al. Hypoxia and hypoxia-inducible factor 1 repress SEMA4B expression to promote non-small cell lung cancer invasion. TUMOR BIOLOGY 35:4949-4955(2014).
  • Q&As
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