|Official Full Name||sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A|
|Background||The transmembrane semaphorin SEMA6A is expressed in developing neural tissue and is required for proper development of the thalamocortical projection (Leighton et al., 2001 [PubMed 11242070]).[supplied by OMIM, Feb 2011]|
|Synonyms||SEMA6A; sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A; VIA; SEMA; HT018; SEMAQ; SEMA6A1; semaphorin-6A; SEMA6A-1; sema VIa; semaphorin VIA; semaphorin 6A-1; semaphorin-6A-1;|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
SEMA6A involved in several pathways and played different roles in them. We selected most pathways SEMA6A participated on our site, such as Axon guidance, which may be useful for your reference. Also, other proteins which involved in the same pathway with SEMA6A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Axon guidance||AGRN; AP2A2; EFNA1B; DOCK1; CXCL12; RAC1; UNC5A; EPHA4A; ABLIM3; ABLIM1|
SEMA6A has several biochemical functions, for example, chemorepellent activity, protein binding, semaphorin receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SEMA6A itself. We selected most functions SEMA6A had, and list some proteins which have the same functions with SEMA6A. You can find most of the proteins on our site.
|chemorepellent activity||SEMA4D; SEMA4C; NRG3; SEMA3C; SEMA3D; SEMA6E; FLRT2; SEMA3E; SEMA4BA; FLRT3|
|protein binding||TRAF4; EIF4E2; GPA33; CCDC6; ITGB1BP3; DLG3; EPC1; THBS4; RHO; SPINK1|
|semaphorin receptor binding||SEMA5A; SEMA4E; SEMA3D; SEMA4C; SEMA3GA; SEMA4D; SEMA6C; SEMA3GB; SEMA3H; SEMA6DL|
SEMA6A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SEMA6A here. Most of them are supplied by our site. Hope this information will be useful for your research of SEMA6A.
SMAD2; SORBS2; SH3RF1; SORBS1; ITSN2