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SETD1B

  • Official Full Name

    SET domain containing 1B

  • Overview

    SET1B is a component of a histone methyltransferase complex that produces trimethylated histone H3 at Lys4 (Lee et al.,;2007 (PubMed 17355966)).
  • Synonyms

    SETD1B; SET domain containing 1B; histone-lysine N-methyltransferase SETD1B; KIAA1076; KMT2G; Set1B; hSET1B; lysine N-methyltransferase 2G; SET domain-containing protein 1B; FLJ20803;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • E.coli
  • HEK293
  • Mammalian Cell
  • His
  • His (Fc)
  • Avi
  • His|GST
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human SETD1B-185H Recombinant Human SET1B Complex Protein, His/GST-tagged E.coli His/GST
Human SETD1B-3213H Recombinant Human SETD1B protein, His-tagged E.coli His 867-1044 aa
Mouse SETD1B-14978M Recombinant Mouse SETD1B Protein Mammalian Cell His
Mouse SETD1B-8066M Recombinant Mouse SETD1B Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse SETD1B-8066M-B Recombinant Mouse SETD1B Protein Pre-coupled Magnetic Beads HEK293
Chicken SETD1B-2366C Recombinant Chicken SETD1B Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • SETD1B Related Articles

SETD1B involved in several pathways and played different roles in them. We selected most pathways SETD1B participated on our site, such as Lysine degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with SETD1B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Lysine degradationAGPHD1;WBP7;EHMT2;PLOD2;MLL5;ALDH7A1;HYKK.2;HADHA;GCDHA

SETD1B has several biochemical functions, for example, RNA binding, histone-lysine N-methyltransferase activity, methyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SETD1B itself. We selected most functions SETD1B had, and list some proteins which have the same functions with SETD1B. You can find most of the proteins on our site.

Function Related Protein
RNA bindingATXN1L;IGF2BP2A;DDX17;DDX43;RCAN3;RBM44;AKAP1;RNASET2;WT1
histone-lysine N-methyltransferase activitySMYD2B;SMYD1;EHMT2;AAAS;SETDB1;EHMT1A;EZH1;SUV39H1A;SETD8
methyltransferase activityRNMTL1A;GAMT;METTL21D;PRDM6;METTL8;NTMT1;ASMT2;COMTB;DNMT3
molecular_functionTMEM107;TMEM106BA;DEFB33;MAGEA8;BEX6;CX34.4;RPL39;a1BG;CML3
nucleic acid bindingRBPMS2;EIF4A1B;RBM12B1;GTF2H2;ZFP335;PRDM9;HIVEP2;ZFP74;ZBTB2A
nucleotide bindingNTRK2B;NAIP1;CPEB3;MATR3;ATP2B1A;RAP1AA;MAP2K4A;HNRNPR;SETX
transferase activityPKDCCA;PIK3R3B;ZDHHC16B;CDYL;TAOK1;LYCAT;SRPK1A;SULT2ST1;Chst5

SETD1B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SETD1B here. Most of them are supplied by our site. Hope this information will be useful for your research of SETD1B.

Qadota, H; McGaha, LA; et al. A novel protein phosphatase is a binding partner for the protein kinase domains of UNC-89 (obscurin) in Caenorhabditis elegans. MOLECULAR BIOLOGY OF THE CELL 19:2424-2432(2008).
Wu, H; Zhang, GY; et al. T cell lines specific for a synthetic Heymann nephritis peptide derived from the receptor-associated protein. CLINICAL AND EXPERIMENTAL IMMUNOLOGY 121:157-164(2000).
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