SETD8
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Official Full Name
SET domain containing (lysine methyltransferase) 8
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Overview
SET domain-containing lysine methyltransferase 8 (SET8), also known as PR/SET domain-containing protein 7 (PR/SET7), is a member of a family of histone lysine methyltransferases, each of which contains a conserved catalytic SET domain originally identifie -
Synonyms
SETD8; SET domain containing (lysine methyltransferase) 8; N-lysine methyltransferase SETD8; KMT5A; PR Set7; SET07; SET8; PR/SET07; H4-K20-HMTase SETD8; lysine N-methyltransferase 5A; SET domain-containing protein 8; PR/SET domain containing protein 8; PR;
- Recombinant Proteins
- Cell & Tissue Lysates
- Human
- E.coli
- HEK293
- Sf9 Insect Cell
- GST
- His
- N/A
Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
---|---|---|---|---|---|---|
Human | SETD8-461H | Recombinant Human SETD8, GST-tagged | E.coli | GST | ||
Human | SETD8-2608H | Recombinant Human SETD8, His-tagged | E.coli | His | 1-352aa | |
Human | SETD8-187H | Recombinant Human SETD8 Protein, His-tagged | E.coli | His | 190-352 | |
Human | SETD8-1631H | Recombinant Human SET Domain Containing (lysine methyltransferase) 8, GST-tagged | Sf9 Insect Cell | GST | ||
Human | SETD8-886H | Recombinant Human SETD8, None tagged | E.coli | N/A | ||
Human | SETD8-6964H | Recombinant Human SETD8, GST-tagged | Sf9 Insect Cell | GST | Full length | |
Human | SETD8-1924HCL | Recombinant Human SETD8 293 Cell Lysate | HEK293 | N/A |
- Involved Pathway
- Protein Function
- Interacting Protein
- SETD8 Related Articles
- SETD8 Related Research Area
SETD8 involved in several pathways and played different roles in them. We selected most pathways SETD8 participated on our site, such as Lysine degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with SETD8 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Lysine degradation | SETD8B;EHMT1A;AGPHD1;EHHADH;PLOD3;WHSC1;MLL1;SUV39H1;EHMT1 |
SETD8 has several biochemical functions, for example, histone-lysine N-methyltransferase activity, p53 binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SETD8 itself. We selected most functions SETD8 had, and list some proteins which have the same functions with SETD8. You can find most of the proteins on our site.
Function | Related Protein |
---|---|
histone-lysine N-methyltransferase activity | SUV420H1;EHMT1B;EZH1;SETD1B;SUV39H1A;AAAS;SETD7;WHSC1L1;MLL1 |
p53 binding | RNF34;TRIM29;CDKN2A;BANP;NUAK1;SMYD2;TP53;RFWD3;ZFP385C |
protein binding | UBE3A;CDIPT;ABCG2;TMEM27;CCDC11;TRAPPC2;SAMD4A;FIS1;MLH3 |
protein-lysine N-methyltransferase activity | METTL8;SETD7;AAAS;METTL7B;METTL21D;IRF4;EZH2;SETD8;PRMT8B |
transcription corepressor activity | JUB;AEBP1;WWTR1;CCND1;HOMEZA;TRIM28;SAP18;HOMEZ;CRYM |
SETD8 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SETD8 here. Most of them are supplied by our site. Hope this information will be useful for your research of SETD8.
HIST2H4B; TWIST1; FAM9A
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