SFPI1
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Official Full Name
SFFV proviral integration 1 -
Synonyms
SFPI1;SFFV proviral integration 1;transcription factor PU.1;31 kDa Transforming Protein;31 kDa-transforming protein;Hematopoietic transcription factor PU.1;OF;PU.1;SPI 1 proto oncogene;SPI A;Spi1;SPI1_HUMAN;Spleen focus forming virus (SFFV) proviral integration oncogene spi1;Spleen Focus Forming Virus Proviral Integration Oncogene;SFFV proviral integration 1 protein;Dis1;Dis-1;Spi-1;Sfpi-1;Tcfpu1;Tfpu.1
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| SFPI1-15006M | Recombinant Mouse SFPI1 Protein | Mammalian Cells | Mouse | His |
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| SFPI1-8082M | Recombinant Mouse SFPI1 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | Avi&Fc&His |
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| SFPI1-8082M-B | Recombinant Mouse SFPI1 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
SFPI1 involved in several pathways and played different roles in them. We selected most pathways SFPI1 participated on our site, such as Osteoclast differentiation,HTLV-I infection,Epstein-Barr virus infection, which may be useful for your reference. Also, other proteins which involved in the same pathway with SFPI1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Osteoclast differentiation | IFNAR1,MAP2K6,LILRB5,PPP3CA,PIK3R2,FOS,IFNAR2,MAP3K7,FHL2,ITGB3 |
| Acute myeloid leukemia | NRAS,MAP2K1,BAD,RAF1,RPS6KB2,HRAS,IKBKG,PIK3CB,RELA,LEF1 |
| Transcriptional misregulation in cancer | NCOR1,ZBTB16,SIX4,BCL2L1,GZMB,MAX,PAX3,BCL2A1A,WHSC1,BMI1 |
| HTLV-I infection | XPO1,XIAP,FZD1,SLC25A5,PCNA,XBP1,WNT10B,H2-Q10,HLA-DOA,ATM |
| Epstein-Barr virus infection | TRAF5,POLR3K,HLA-B,LYN,MAPK12,RBPJL,MAPK9,MAPK13,PTMA,SYK |
| Pathways in cancer | RELA,HRAS,HIF1A,HSP90B1,FGFR3,AKT1,LAMA5,NCOA4,GSTP1,FIGF |
Protein Function
SFPI1 has several biochemical functions, for example, DNA binding,NFAT protein binding,RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SFPI1 itself. We selected most functions SFPI1 had, and list some proteins which have the same functions with SFPI1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding | ZFPM2A,ZFP746,ZNF148,CC2D1B,IFI203,BCL11AA,SNAI1,KLF16,POU4F2,HINFP |
| RNA polymerase II transcription factor binding | SPI1,PITX2,GATA5,GATA2B,GATA1A,GATA2,GATA6,ZFPM1,MEF2A,TRPS1 |
| DNA binding | ZNF410,SPTY2D1,KDM2AA,SURF6,MCM6L,ZNF134,LHFP,NR6A1A,POLR2K,C19orf40 |
| RNA polymerase II distal enhancer sequence-specific DNA binding | TFAP2C,BACH2,NR5A2,TAL1,NFATC1,MEOX2,JUN,NR2F6,T,HNRNPC |
| core promoter binding | NONO,IFI16,RB1,MYBBP1A,NKX3-1,SFPQ,KDM3A,SPI1,HDAC6,KLF4 |
| NFAT protein binding | MAPK14,SPI1,FOXP3,PPARA,GATA4 |
| RNA binding | RTCA,NPM1,KHDC1C,EIF4EA,RBMS2,RNASEL4,EWSR1,NCBP1,NABP1,SRP14 |
| transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding | FOXC1,MEIS1,MEF2A,SNAI2,RFX1,MYOD1,OLIG2,USF1,SPI1,NR5A2 |
| transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding | NFE2L2,MIXL1,BACH1,PROP1,NFKB1,SIX3,CDX1,SUB1,RELA,SPI1 |
Interacting Protein
SFPI1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SFPI1 here. Most of them are supplied by our site. Hope this information will be useful for your research of SFPI1.
Nono;Cd1d1;Hoxa10;Gfi1;GFI1;id3_mouse_gene;ari3a_mouse_gene;cd1d1_mouse_gene;vpre2_mouse_gene;Smad3
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