SGK2
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Official Full Name
serum/glucocorticoid regulated kinase 2 -
Overview
Serum and glucocorticoid-inducible kinase (SGK) is a serine/threonine kinase closely related to Akt. SGK is rapidly induced in response to a variety of stimuli, including serum, glucocorticoid, follicle stimulating hormone, osmotic shock, and mineralocort
Recombinant Proteins
- Human
- Rat
- Mouse
- E.coli
- Sf9 Cells
- Mammalian Cells
- HEK293
- Insect Cells
- Sf21 Cells
- GST
- His
- T7
- Non
- DDK
- Myc
- Avi
- Fc
Involved Pathway
SGK2 involved in several pathways and played different roles in them. We selected most pathways SGK2 participated on our site, such as FoxO signaling pathway,Insulin Signaling,Ion channel transport, which may be useful for your reference. Also, other proteins which involved in the same pathway with SGK2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| FoxO signaling pathway | BRAF,SMAD4,INSRA,PIK3CG,AKT1,SIRT1,SLC2A4,HRASA,PIK3CB,BCL6 |
| Transmembrane transport of small molecules | SLC12A7,SLC17A1,SLC20A1A,SLC38A4,SLC7A8A,SLC5A3A,FTH1A,TRPM6,AQP10A,ATP2B1B |
| Insulin Signaling | GSK3AB,SNAP25A,MAP3K9,ARHGAP33,MAP4K5,REG1A,STXBP3A,CAP1,GRB14,KIF5B |
| Stimuli-sensing channels | TRPC4AP,TPCN1,TRPC4APA,ANO10,TTYH3B,ASIC1A,TRPC4A,ANO8,TSC22D3,ANO6 |
| Ion channel transport | BEST1,FXYD6-FXYD2,ANO10,CLCN1A,ATP13A5,TTYH2,CLCN2,GLRBA,TTYH3B,ATP7B |
| PI3K-Akt signaling pathway | CSH1,EFNA2,CSF1,PIK3AP1,CHAD,CSF3R,CSF1R,EFNA4,COMP,PRP2 |
Protein Function
SGK2 has several biochemical functions, for example, ATP binding,calcium channel regulator activity,chloride channel regulator activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SGK2 itself. We selected most functions SGK2 had, and list some proteins which have the same functions with SGK2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| calcium channel regulator activity | CACNA2D4,NPY,STIM1B,TSPAN13A,NRXN3,STIM2,CACNA2D1,CRISP1,GNB2,CACNA2D1A |
| sodium channel regulator activity | FXYD6,SCN3B,FXYD4,SCN2B,SCLT1,FXYD2,GPLD1,GPD1L,PTPN3,PRSS30 |
| potassium channel regulator activity | KCNAB2,KCNE1L,ABCC9,KCNAB1,KCNIP3,DPP6,KCNMB1,KCNIP2,KCNMB2,CHP |
| protein serine/threonine kinase activity | CAMK1DB,NEK10,CDK15,DCAMKL2,OBSCN,CAMK1GA,MAP3K8,CSNK1A1,MAP4K3,MAP4K2 |
| ATP binding | FKBP4,NOLC1,TOR1B,FGR,NEK8,SMOK2B,P2RX8,PHKG1B,PBK,KHK |
| chloride channel regulator activity | BSND,CHRNA7,SGK3,SLC9A3R1,SGK1,SGK2A,SGK2B |
Interacting Protein
SGK2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SGK2 here. Most of them are supplied by our site. Hope this information will be useful for your research of SGK2.
HSP90AB1;IL3RA;DDX5;TCP1;CCT6A;CCT5;CCT3;CCT8;CCT4;ILF3;FKBP5;CCT7
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