SGK2

  • Official Full Name

    serum/glucocorticoid regulated kinase 2

  • Overview

    Serum and glucocorticoid-inducible kinase (SGK) is a serine/threonine kinase closely related to Akt. SGK is rapidly induced in response to a variety of stimuli, including serum, glucocorticoid, follicle stimulating hormone, osmotic shock, and mineralocort

  • Synonyms

    SGK2;serum/glucocorticoid regulated kinase 2;serine/threonine-protein kinase Sgk2;H-SGK2;dJ138B7.2

Recombinant Proteins

  • Human
  • Rat
  • Mouse
  • E.coli
  • Sf9 Cells
  • Mammalian Cells
  • HEK293
  • Insect Cells
  • Sf21 Cells
  • GST
  • His
  • T7
  • Non
  • DDK
  • Myc
  • Avi
  • Fc

    Involved Pathway

    SGK2 involved in several pathways and played different roles in them. We selected most pathways SGK2 participated on our site, such as FoxO signaling pathway,Insulin Signaling,Ion channel transport, which may be useful for your reference. Also, other proteins which involved in the same pathway with SGK2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    PI3K-Akt signaling pathway EFNA2,CSH1,PRP2,CSH2,CSF3,CDC37,CSF1,CSF3R,COMP,LAMC3
    Insulin Signaling GSK3AB,STXBP2,EHD1,RHOJ,STXBP3,MINK1,MAP3K2,GRB14,MYO1C,ARHGAP33
    Stimuli-sensing channels TRPC5A,CLCN6,TSC22D3,ANO7,TRPA1B,TPCN1,SLC9A10,TRPC4APB,ANO5B,SLC9B2
    Transmembrane transport of small molecules SLC30A5,TRPA1A,OSTM1,SLC27A4,SLC2A15A,ATP7B,SLC6A15,SLC39A2,SLC17A3,SLC35D1A
    FoxO signaling pathway PRKAB1A,SIRT1,SMAD4,SLC2A4,PIK3R2,IRS2,Fasl,IRS4,SMAD3,S1PR4
    Ion channel transport FXYD6,GLRBA,CLCN1,ANO10A,CLCN5,SLC9B2,HTR3C,ATP1A1A.4,WNK2,BEST1

    Protein Function

    SGK2 has several biochemical functions, for example, ATP binding,calcium channel regulator activity,chloride channel regulator activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SGK2 itself. We selected most functions SGK2 had, and list some proteins which have the same functions with SGK2. You can find most of the proteins on our site.

    Function Related Protein
    chloride channel regulator activity SGK3,SLC9A3R1,SGK2A,SGK1,SGK2B,BSND,CHRNA7
    potassium channel regulator activity ANK2,SGK2A,KCNE1L,ARPP19A,DRD4,KCNE1,ARPP19,KCNIP4,AMIGO1,KCNMB1
    protein serine/threonine kinase activity ADCK4,ACVRL1,LATS1,SQSTM1,KSR2,ACVR1B,FAM20C,DYRK2,MAPK8,EIF2AK3
    ATP binding PRKACBB,CDK10,CERK,PSKH2,HYOU1,HSPA9,CHD8,CARKD,DDX31,CSNK1G2B
    calcium channel regulator activity PRKG1,CACNA2D1,CACNA2D2,CACNA2D4,STIM1A,GRM7,TSPAN13,CACNB2,HPCAL4,STIM2
    sodium channel regulator activity SCN1BB,FXYD3,NEDD4L,RANGRF,PKP2,SCN1BA,SCN2B,FXYD5,SGK2B,SCN1B

    Interacting Protein

    SGK2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SGK2 here. Most of them are supplied by our site. Hope this information will be useful for your research of SGK2.

    HSP90AB1;IL3RA;DDX5;TCP1;CCT6A;CCT5;CCT3;CCT8;CCT4;ILF3;FKBP5;CCT7

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