SGK2

  • Official Full Name

    serum/glucocorticoid regulated kinase 2

  • Overview

    Serum and glucocorticoid-inducible kinase (SGK) is a serine/threonine kinase closely related to Akt. SGK is rapidly induced in response to a variety of stimuli, including serum, glucocorticoid, follicle stimulating hormone, osmotic shock, and mineralocort

  • Synonyms

    SGK2;serum/glucocorticoid regulated kinase 2;serine/threonine-protein kinase Sgk2;H-SGK2;dJ138B7.2

Recombinant Proteins

  • Human
  • Rat
  • Mouse
  • E.coli
  • Sf9 Cells
  • Mammalian Cells
  • HEK293
  • Insect Cells
  • Sf21 Cells
  • GST
  • His
  • T7
  • Non
  • DDK
  • Myc
  • Avi
  • Fc

    Involved Pathway

    SGK2 involved in several pathways and played different roles in them. We selected most pathways SGK2 participated on our site, such as FoxO signaling pathway,Insulin Signaling,Ion channel transport, which may be useful for your reference. Also, other proteins which involved in the same pathway with SGK2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Transmembrane transport of small molecules SLC39A3,SLC1A2B,SLC9A3.1,SLC15A4,TRPC4APA,SLC9A6B,SLC30A5,SLC6A11,FKBP1B,SLC9A5
    Stimuli-sensing channels SLC9A10,CLCN7,ANO5,TRPM1,ANO7,CLCN4,CLCN1A,ANO5B,NHEDC1,ANO10
    Ion channel transport HTR3C,TRPC4,UNC79,MCOLN3,CLCN2,CLIC2,Ano3,ANO10,TRPM6,TPCN1
    FoxO signaling pathway STK11,S1PR1,HRAS,PIK3CG,PRKAG2,MAP2K2B,PRKAA1,IL7R,PIK3R3A,FBXO25
    PI3K-Akt signaling pathway CSH,PRP2,CSF3R,LOC608458,CSH1,CSF3,CSF1R,CSH2,CDC37,LAMC3
    Insulin Signaling EHD1,MYO1C,ARHGAP33,RRAD,MAPK4,STXBP4,STXBP3A,STXBP2,GRB10,MINK1

    Protein Function

    SGK2 has several biochemical functions, for example, ATP binding,calcium channel regulator activity,chloride channel regulator activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SGK2 itself. We selected most functions SGK2 had, and list some proteins which have the same functions with SGK2. You can find most of the proteins on our site.

    Function Related Protein
    ATP binding DDX56,P2RY4,EIF4A1,P2RX3B,KATNA1,DHX8,TMEM38A,SMC1A,TAP2,MLH1
    chloride channel regulator activity CHRNA7,SGK2A,SLC9A3R1,BSND,SGK1,SGK2B,SGK3
    sodium channel regulator activity SCN1BB,SGK2B,PKP2,YWHAH,CAV3,FXYD5,NEDD4L,SGK2A,PRSS30,FXYD3
    protein serine/threonine kinase activity RPS6KA3A,MAPK8,PRKCHA,DMPK,CSNK1G2B,NEK1,HIPK1,STK38L,NUAK1,MAPK8A
    calcium channel regulator activity STIM1,TMEM110,NRXN2,GRM2,NPY,PRKCB,TSPAN13A,SGK2B,GRM6A,PRKG1
    potassium channel regulator activity KCNE1L,DRD4,AKAP9,KCNAB2,DRD2,PRKCZ,KCNAB3,KCNE2,SGK2B,DPP6

    Interacting Protein

    SGK2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SGK2 here. Most of them are supplied by our site. Hope this information will be useful for your research of SGK2.

    HSP90AB1;IL3RA;DDX5;TCP1;CCT6A;CCT5;CCT3;CCT8;CCT4;ILF3;FKBP5;CCT7

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