SGK2

  • Official Full Name

    serum/glucocorticoid regulated kinase 2

  • Overview

    Serum and glucocorticoid-inducible kinase (SGK) is a serine/threonine kinase closely related to Akt. SGK is rapidly induced in response to a variety of stimuli, including serum, glucocorticoid, follicle stimulating hormone, osmotic shock, and mineralocort

  • Synonyms

    SGK2;serum/glucocorticoid regulated kinase 2;serine/threonine-protein kinase Sgk2;H-SGK2;dJ138B7.2

Recombinant Proteins

  • Human
  • Rat
  • Mouse
  • E.coli
  • Sf9 Cells
  • Mammalian Cells
  • HEK293
  • Insect Cells
  • Sf21 Cells
  • GST
  • His
  • T7
  • Non
  • DDK
  • Myc
  • Avi
  • Fc

    Involved Pathway

    SGK2 involved in several pathways and played different roles in them. We selected most pathways SGK2 participated on our site, such as FoxO signaling pathway,Insulin Signaling,Ion channel transport, which may be useful for your reference. Also, other proteins which involved in the same pathway with SGK2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    PI3K-Akt signaling pathway CSF3R,PRP2,LAMC3,COMP,CSH1,EFNA2,CSF1R,EFNA3,EFNA4,CSH2
    Transmembrane transport of small molecules ABCC2,SLC9B2,SLCO2B1,SLC7A6,ABCB8,WNK2,ATP1A1A.4,SLC2A15A,SLC34A3,SLC13A5A
    Ion channel transport CLCN7,FXYD3,TRPC4APB,BEST3,GABRR2A,SLC17A3,CLCN6,TRPC4,FXYD6-FXYD2,TRPV3
    Insulin Signaling MYO1C,MAPK6,RRAD,RHOJ,INPP4AA,STXBP4,GRB10,CAP1,SNAP25A,REG1A
    FoxO signaling pathway IGF1RB,ATG12,FOXO3,NLK1,EGFRA,SGK3,CCND2,MAPK11,CDKN2D,MAP2K2A
    Stimuli-sensing channels TRPC5,CLCN4-2,ANO10,TRPA1B,ANO6,TRPM1,TRPV3,TTYH3B,TSC22D3,ASIC1A

    Protein Function

    SGK2 has several biochemical functions, for example, ATP binding,calcium channel regulator activity,chloride channel regulator activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SGK2 itself. We selected most functions SGK2 had, and list some proteins which have the same functions with SGK2. You can find most of the proteins on our site.

    Function Related Protein
    protein serine/threonine kinase activity PLK3,TESK1,TRPM6,MAP2K6,STK16,MAST2,PRKAA2,MAP3K12,RIOK3,MAP3K4
    potassium channel regulator activity CHP,YWHAE,KCNV1,SGK1,KCNMB3,KCNIP4,SUMO1,SGK3,ARPP19A,ARPP19
    sodium channel regulator activity NEDD4L,SCN1BB,AGT,SGK2A,SCN3B,GPLD1,FGF12,CAV3,RANGRF,FXYD4
    calcium channel regulator activity SGK2A,CACNA2D2,CAV3,NRXN3,GRM7,STIM1,CACNA2D3,GRM2,SGK3,PLN
    ATP binding CARNS1,KIF21A,SMARCA4,RIPK2,NETO2,TLK2,UBE2D2A,ABCC10,ATP1A4,NOL9
    chloride channel regulator activity SLC9A3R1,SGK2B,BSND,SGK3,CHRNA7,SGK1,SGK2A

    Interacting Protein

    SGK2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SGK2 here. Most of them are supplied by our site. Hope this information will be useful for your research of SGK2.

    HSP90AB1;IL3RA;DDX5;TCP1;CCT6A;CCT5;CCT3;CCT8;CCT4;ILF3;FKBP5;CCT7

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