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Official Full Name Src homology 2 domain containing adaptor protein B
Background SH2 domain-containing adapter protein B is a protein that in humans is encoded by the SHB gene.
Synonyms SHB; Src homology 2 domain containing adaptor protein B; SHB (Src homology 2 domain containing) adaptor protein B , SHB adaptor protein (a Src homology 2 protein); SH2 domain-containing adapter protein B; SHB adaptor protein (a Src homology 2 protein); S
    • Species :
    • Human
    • Mouse
    • Source :
    • E.coli
    • Mammalian Cell
    • Tag :
    • His
    • T7
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human SHB-1948H Recombinant Human SHB protein, His & T7-tagged E.coli His/T7
    Human SHB-290H Recombinant Human SHB Protein, His-tagged E.coli His
    Mouse SHB-15088M Recombinant Mouse SHB Protein Mammalian Cell His
    Mouse Shb-1949M Recombinant Mouse Shb protein, His & T7-tagged E.coli His/T7

    SHB involved in several pathways and played different roles in them. We selected most pathways SHB participated on our site, such as Axon guidance, Developmental Biology, EPH-Ephrin signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with SHB were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Axon guidance GNAI1; ABL1; CREB1B; DLG3; ARHGEF12; FGF18B; CXCL12; COL9A1; NFATC4; EPHB1
    Developmental Biology CFL1; LGI2A; LGI1B; SIAH2; SPRED3; MEF2AA; ITGB3A; CD24; SPTA1; CLASP1
    EPH-Ephrin signaling AP2S1; EPHB4A; EFNA2; KALRN; CLTC; EFNA3B; MYL12A; EFNA1B; EFNA1; AP2B1
    EPHA-mediated growth cone collapse EFNA4; EFNA2; EPHA4A; EFNA1B; EPHA2A; MYL12B; EFNA2A; EPHA10; SHB; EFNA3
    IL-2 Signaling Pathway CISH; SHB; ITM2BA; NMI; CD53
    Signal Transduction NPB; GMIP; CDC42EP3; UTS2; CRABP1; TJP2B; ARHGEF18A; GPBAR1; GPR18; FABP11A
    Signaling by VEGF AXL; SHB; NRP2; NRP2A; NRP2B; JUPA; DSCAMA
    T Cell Receptor Signaling Pathway LCK; NFATC2; PPP3CB; IKBKB; PIK3CA; PDPK1; PPP3R1; FOS; VAV2; MAP2K2

    SHB has several biochemical functions, for example, SH3/SH2 adaptor activity, glycoprotein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SHB itself. We selected most functions SHB had, and list some proteins which have the same functions with SHB. You can find most of the proteins on our site.

    Function Related Protein
    SH3/SH2 adaptor activity GRB2; PAG1; TOB1; RUSC1; CHN1; ARHGAP4; CNTNAP1; ARHGAP1; SH2D1A; HSH2D
    glycoprotein binding CDH1; FBXO2; CNTN2; SELP; LACRT; LRRK2; Shh; CANX; SERPINA1A; CALR

    SHB has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SHB here. Most of them are supplied by our site. Hope this information will be useful for your research of SHB.

    Pdgfra; FGFR1

    Sato, S; Kamada, H; et al. Identification of the Cancer Cell Proliferation and Survival Functions of proHB-EGF by Using an Anti-HB-EGF Antibody. PLOS ONE 8:-(2013).
    Tsuji, I; Sato, S; et al. Characterization of a variety of neutralizing anti-heparin-binding epidermal growth factor-like growth factor monoclonal antibodies by different immunization methods. MABS 4:732-739(2012).

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