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  • Official Full Name

    Src homology 2 domain containing adaptor protein B

  • Overview

    SH2 domain-containing adapter protein B is a protein that in humans is encoded by the SHB gene.
  • Synonyms

    SHB; Src homology 2 domain containing adaptor protein B; SHB (Src homology 2 domain containing) adaptor protein B , SHB adaptor protein (a Src homology 2 protein); SH2 domain-containing adapter protein B; SHB adaptor protein (a Src homology 2 protein); S;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • E.coli
  • HEK293
  • Mammalian Cell
  • His
  • His (Fc)
  • Avi
  • His|T7
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human SHB-290H Recombinant Human SHB Protein, His-tagged E.coli His
Human SHB-1948H Recombinant Human SHB protein, His & T7-tagged E.coli His/T7 Ala252~Arg507 (Accession # Q15464)
Human SHB-6281H Recombinant Human SHB Protein (Ala252-Arg507), N-His tagged E.coli N-His Ala252-Arg507
Mouse SHB-15088M Recombinant Mouse SHB Protein Mammalian Cell His
Mouse SHB-8139M Recombinant Mouse SHB Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse SHB-8139M-B Recombinant Mouse SHB Protein Pre-coupled Magnetic Beads HEK293
Mouse Shb-1949M Recombinant Mouse Shb protein, His & T7-tagged E.coli His/T7 Ser248~Leu484 (Accession # Q6PD21)
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • SHB Related Articles
  • SHB Related Research Area
  • SHB Related Signal Pathway

SHB involved in several pathways and played different roles in them. We selected most pathways SHB participated on our site, such as Axon guidance, Developmental Biology, EPH-Ephrin signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with SHB were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
EPHA-mediated growth cone collapseEPHA2A;MYL9;EPHA2;SHB;MYL12B;EPHA10;EFNA4;EPHA4A;KDR
IL-2 Signaling PathwayCISH;SHB;ITM2BA;CD53;NMI
T Cell Receptor Signaling PathwaySLA1;RELA;EVLB;IKBKG;PIK3CA;CD8A;PAK6;MUC1;PAK2

SHB has several biochemical functions, for example, SH3/SH2 adaptor activity, glycoprotein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SHB itself. We selected most functions SHB had, and list some proteins which have the same functions with SHB. You can find most of the proteins on our site.

Function Related Protein
SH3/SH2 adaptor activityIRS4;ARHGAP1;NCK1;SOCS2;GRB10;SLA2;CD28;ITSN2;PAG1
glycoprotein bindingTFRC;SDC1;LCK;F7;CSNK1D;FBXO27;SERPINA1D;BBC3;VIM

SHB has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SHB here. Most of them are supplied by our site. Hope this information will be useful for your research of SHB.

Pdgfra; FGFR1

Sato, S; Kamada, H; et al. Identification of the Cancer Cell Proliferation and Survival Functions of proHB-EGF by Using an Anti-HB-EGF Antibody. PLOS ONE 8:-(2013).
Tsuji, I; Sato, S; et al. Characterization of a variety of neutralizing anti-heparin-binding epidermal growth factor-like growth factor monoclonal antibodies by different immunization methods. MABS 4:732-739(2012).
  • Q&As
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