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Official Full Name SHC (Src homology 2 domain containing) transforming protein 2
Background SHC-transforming protein 2 is a protein that in humans is encoded by the SHC2 gene, SHC2 has been shown to interact with Kinase insert domain receptor.
Synonyms SHC2; SHC (Src homology 2 domain containing) transforming protein 2; SHC-transforming protein 2; neuronal Shc adaptor homolog; SCK; SHCB; SLI; Protein Sck; SH2 domain protein C2; SHC transforming protein 2; Src homology 2 domain containing transforming protein C2; SHC-transforming protein B; src homology 2 domain-containing-transforming protein C2
    • Species :
    • Mouse
    • Rat
    • Zebrafish
    • Source :
    • E.coli
    • Mammalian Cell
    • Tag :
    • His
    • T7
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Mouse SHC2-15091M Recombinant Mouse SHC2 Protein Mammalian Cell His
    Mouse Shc2-1745M Recombinant Mouse Shc2 protein, His & T7-tagged E.coli His/T7
    Rat SHC2-5390R Recombinant Rat SHC2 Protein Mammalian Cell His
    Zebrafish SHC2-4062Z Recombinant Zebrafish SHC2 Mammalian Cell His

    SHC2 involved in several pathways and played different roles in them. We selected most pathways SHC2 participated on our site, such as ErbB signaling pathway, Ras signaling pathway, Chemokine signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with SHC2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    ErbB signaling pathway PIK3CA; PAK4; HRAS; PIK3R3B; MAPK8B; PAK2A; NRAS; MAP2K7; BTC; PRKCBB
    Ras signaling pathway FGF18; FGF20; ETS2; GNG12; KIT; CDC42; RALBP1; NF1; RASSF1; KSR2
    Chemokine signaling pathway GRK1; STAT1; ROCK2; CCL26; CCL18; CCL2; IKBKB; XCL2; NCF1; CCL25
    Phospholipase D signaling pathway PLA2G4F; Pdgfa&Pdgfb; PLCG1; NRAS; GNAS; AGTR1A; PIK3CD; LPAR4; PLD1; CXCR1
    VEGF signaling pathway PTGS2A; SH2D2A; RAF1B; CASP9; PRKCG; PPP3R1; RAC3B; SPHK2; PRKCBA; PRKCB
    Natural killer cell mediated cytotoxicity SH2D1A; HLA-A; Ifna11; FASLG; NFATC2; SH2D1B; ICAM1; NCR3; IFNAR2; H60a
    Neurotrophin signaling pathway RPS6KA2; ATF4; GAB1; CAMK2A; PIK3CA; CALM2; SH2B1; SH2B2; TRP53; NTRK1
    Insulin signaling pathway SHC2; PIK3R5; INPP5K; CBL; MKNK2A; INS1; PPP1CB; PPP1CA; PKLR; FBP1A
    Estrogen signaling pathway FKBP4; CREB3L3; HRAS; CREB3L1; SHC4; GABBR1; ESR2; ITPR1; HSP90AB1; CALML3
    Prolactin signaling pathway AKT1; CCND1; FOS; GALT; ESR2; SHC3; IRF1; TNFRSF11A; PPIB; STAT5A
    Alcoholism GNB4; H3F3A; CALML5; SLC18A2; GRIN3A; GRB2; H2AFZ; H2AFY; HDAC4; GNB5
    Bacterial invasion of epithelial cells CBLB; MET; RHOA; VCL; CTNNA1; ELMO2; SHC4; CRK; CTTN; WASL
    Chronic myeloid leukemia RAF1; CTBP2; HDAC1; PIK3R2; IKBKG; SHC1; CCND1; CRKL; NRAS; CTBP1

    SHC2 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by SHC2 itself. We selected most functions SHC2 had, and list some proteins which have the same functions with SHC2. You can find most of the proteins on our site.

    Function Related Protein

    SHC2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SHC2 here. Most of them are supplied by our site. Hope this information will be useful for your research of SHC2.


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