| Official Full Name | SHC (Src homology 2 domain containing) family, member 4 |
| Synonyms | SHC4; SHC (Src homology 2 domain containing) family, member 4; SHC-transforming protein 4; rai like protein; RaLP; hShcD; MGC34023; SH2 domain protein C4; SHC (Src homology 2 domain containing) family member 4; SHC 4; SHC; SHC family member 4; SHC transforming protein 4; SHC transforming protein D; SHCD; Src homology 2 domain containing familymember 4; Src homology 2 domain containing transforming protein C4; rai-like protein; OTTHUMP00000162250; SHC-transforming protein D; src homology 2 domain-containing-transforming protein C4 |
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|
SHC4 involved in several pathways and played different roles in them. We selected most pathways SHC4 participated on our site, such as ErbB signaling pathway, Ras signaling pathway, Chemokine signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with SHC4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| ErbB signaling pathway | SHC4; RAF1A; CAMK2B1; AREGB; RPS6KB2; MTOR; PLCG1; NCK2A; SHC2; AKT3A |
| Ras signaling pathway | FGF2; GNB3; RASA1; RHOA; GAB2; RALGDS; FIGF; FGF13; FGF7; SHC1 |
| Chemokine signaling pathway | CCR1; Ccl12; CCL4L1; PIK3CD; PRKACG; GRK1; PRKCB; Ccl21a; CCR7; PIK3R3 |
| Phospholipase D signaling pathway | PLD2; FYN; FCER1G; MS4A2; KIT; RHOA; PLD1; PLA2G4A; PLA2G4C; RAF1 |
| Focal adhesion | IGF1; TNW; RAC3B; GRB2A; PTK2AA; HGF; PTENB; COL5A2A; RAC2; PDGFRB |
| Natural killer cell mediated cytotoxicity | IFNA14; KLRD1; HLA-A; SH3BP2; GRB2; PPP3R1; PIK3CB; HRAS; KLRC2; PAK1 |
| Neurotrophin signaling pathway | MAP2K5; BAX; CAMK2D; RELA; TRP53; MAPK7; TRAF6; CALML5; Fasl; MATK |
| Insulin signaling pathway | PRKCI; CALM4; FLOT1; ARAF; EIF4E2RS1; SLC2A4; EIF4EA; PRKAA2; RAF1A; PTPRF |
| Estrogen signaling pathway | NRAS; MAPK3; PIK3R5; GNAQ; MAP2K2; SHC3; MAP2K1; CALM3; CALM4; KRAS |
| Prolactin signaling pathway | SOS1; STAT1; TH; SHC4; GRB2; ELF5; SLC2A2; PIK3CB; PIK3CA; LHB |
| Alcoholism | H2AFY2; PRKACA; GM14477; CREB3L1; HIST1H4B; CAMKK2; H2BFWT; HIST1H3I; GNG11; PKIA |
| Bacterial invasion of epithelial cells | CD2AP; SEPT2; WASF1; CTNNA2; CAV1; HCLS1; RHOA; CBL; VCL; PIK3CB |
| MicroRNAs in cancer | MDM4; CCND2; SOS1; PIM1; FGFR3; UBE2I; CDCA5; TNC; ZEB1; TTC6 |
| Glioma | PDGFRA; NRAS; CALM4; CAMK2B; ARAF; PLCG1; PIK3CG; SHC4; PRKCB; PIK3R2 |
| Chronic myeloid leukemia | TGFBR1; MDM2; CRKL; CCND1; CBL; HDAC1; SHC1; TRP53; PIK3CB; BRAF |
SHC4 has several biochemical functions, for example, protein binding, protein domain specific binding, protein kinase binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SHC4 itself. We selected most functions SHC4 had, and list some proteins which have the same functions with SHC4. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | CST7; ZNF622; REEP5; MAGEB2; DDR2; RAB18; MYOC; PTRF; SMAD3B; UNC45A |
| protein domain specific binding | PRKAR2B; CALM3; STXBP1; EFS; MYO7A; THRA; WNT1; NEFL; PHRF1; HOMER3 |
| protein kinase binding | CACNB4; PTPRJ; TSKS; HDAC7A; YWHAZ; XBP1; CNTLN; FAF1; CCNA2; SUFU |
| receptor tyrosine kinase binding | HYAL2; SQSTM1; PIK3R2; SHC3; LRP4; ANGPT2A; ANGPT4; PTPN11; FIZ1; ANGPT1 |
SHC4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SHC4 here. Most of them are supplied by our site. Hope this information will be useful for your research of SHC4.
EGFR; MET; AR; KIT
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