SHC4

  • Official Full Name

    SHC (Src homology 2 domain containing) family, member 4
  • Synonyms

    SHC4;SHC (Src homology 2 domain containing) family, member 4;SHC-transforming protein 4;rai like protein;RaLP;hShcD;MGC34023;SH2 domain protein C4;SHC (Src homology 2 domain containing) family member 4;SHC 4;SHC;SHC family member 4;SHC transforming protein 4;SHC transforming protein D;SHCD;Src homology 2 domain containing familymember 4;Src homology 2 domain containing transforming protein C4;rai-like protein;OTTHUMP00000162250;SHC-transforming protein D;src homology 2 domain-containing-transforming protein C4

Recombinant Proteins

  • Human
  • Mouse
  • E.coli
  • Mammalian Cells
  • HEK293
  • GST
  • His
  • Non
  • DDK
  • Myc
  • Avi
  • Fc
Cat.# Product name Source (Host) Species Tag Protein Length Price
SHC4-2656H Recombinant Human SHC4, GST-tagged E.coli Human GST C-term-307aa
SHC4-15093M Recombinant Mouse SHC4 Protein Mammalian Cells Mouse His
SHC4-1861HCL Recombinant Human SHC4 293 Cell Lysate HEK293 Human Non
SHC4-355H Recombinant Human SHC4 Protein, MYC/DDK-tagged, C13 and N15-labeled HEK293 Human DDK&Myc
Shc4-5855M Recombinant Mouse Shc4 Protein, Myc/DDK-tagged HEK293 Mouse DDK&Myc
SHC4-7854H Recombinant Human SHC4 protein, GST-tagged E.coli Human GST
SHC4-8144M Recombinant Mouse SHC4 Protein, His (Fc)-Avi-tagged HEK293 Mouse Avi&Fc&His
SHC4-8144M-B Recombinant Mouse SHC4 Protein Pre-coupled Magnetic Beads HEK293 Mouse

    Involved Pathway

    SHC4 involved in several pathways and played different roles in them. We selected most pathways SHC4 participated on our site, such as ErbB signaling pathway,Ras signaling pathway,Chemokine signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with SHC4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Focal adhesion BCAR1,IGF1,AKT1,PAK2B,COL1A1,ACTN4,PDGFRA,MAPK8B,PDPK1,ITGB7
    Bacterial invasion of epithelial cells SEPT2,CDH1,CTNNA2,CDC42,ELMO3,ELMO1,HCLS1,CAV3,CTTN,PIK3CA
    Phospholipase D signaling pathway GRM6,RALGDS,PLCB1,PDGFB,CXCR1,PLD2,RRAS,TSC2,PDGFD,LPAR2
    Ras signaling pathway PAK7,FGFR1,PLD2,ETS2,VEGFC,FGFR2,FGF3,PDGFA,PAK6,PRKCA
    Alcoholism HIST1H2AP,GNB4,H3F3C,SHC3,SLC6A3,GNB5,HIST1H2BI,HIST1H2BC,GNG10,GNAO1
    Natural killer cell mediated cytotoxicity PIK3R5,TNFRSF10C,CD244,BID,IFNA2,TYROBP,FAS,TNF,PPP3CC,ZAP70
    Estrogen signaling pathway RAF1,ITPR3,ESR2,HSP90AB1,Adcy4,PIK3CA,AKT2,GNAI3,GABBR2,HRAS
    Neurotrophin signaling pathway SHC2,PIK3CB,BCL2,BAX,SHC3,RIPK2,CALM2,RAPGEF1,BDNF,NGF
    Chemokine signaling pathway CCR1,GRK5,PLCB2,BRAF,SRC,GRK1,AMCF-II,PRKACB,CX3CL1,PRKACG

    Protein Function

    SHC4 has several biochemical functions, for example, protein binding,protein domain specific binding,protein kinase binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SHC4 itself. We selected most functions SHC4 had, and list some proteins which have the same functions with SHC4. You can find most of the proteins on our site.

    Function Related Protein
    protein kinase binding LIPE,AKAP5,HCLS1,MAML1,CD24,CCNYL1,CRY1,NEK9,GATA4,EPHA1
    protein binding MATR3,FBXO17,IFT88,MTMR7,ABLIM3,LSM5,MEF2C,ABHD1,MS4A12,TMCO6
    receptor tyrosine kinase binding HYAL2,Flt3l,PITPNM3,ANGPT1,GNB2L1,DOCK4,PLCG1,ANGPT4,SQSTM1,TRP53
    protein domain specific binding VRK2,RCC2,YWHABB,CRB3,PLG,TFDP1,ANGEL1,RAP2B,CNTROB,ETV6

    Interacting Protein

    SHC4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SHC4 here. Most of them are supplied by our site. Hope this information will be useful for your research of SHC4.

    EGFR;MET;AR;KIT

    SHC4 Related Signal Pathway

    Resources

    References

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