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Official Full Name SHC (Src homology 2 domain containing) family, member 4
Synonyms SHC4; SHC (Src homology 2 domain containing) family, member 4; SHC-transforming protein 4; rai like protein; RaLP; hShcD; MGC34023; SH2 domain protein C4; SHC (Src homology 2 domain containing) family member 4; SHC 4; SHC; SHC family member 4; SHC transforming protein 4; SHC transforming protein D; SHCD; Src homology 2 domain containing familymember 4; Src homology 2 domain containing transforming protein C4; rai-like protein; OTTHUMP00000162250; SHC-transforming protein D; src homology 2 domain-containing-transforming protein C4
    • Species :
    • Human
    • Mouse
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Tag :
    • C-Myc/DDK
    • GST
    • His
    • Myc/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human SHC4-1861HCL Recombinant Human SHC4 293 Cell Lysate HEK293 N/A
    Human SHC4-2656H Recombinant Human SHC4, GST-tagged E.coli GST
    Human SHC4-355H Recombinant Human SHC4 Protein, MYC/DDK-tagged, C13 and N15-labeled HEK293 C-Myc/DDK
    Mouse SHC4-15093M Recombinant Mouse SHC4 Protein Mammalian Cell His
    Mouse Shc4-5855M Recombinant Mouse Shc4 Protein, Myc/DDK-tagged HEK293T Myc/DDK

    SHC4 involved in several pathways and played different roles in them. We selected most pathways SHC4 participated on our site, such as ErbB signaling pathway, Ras signaling pathway, Chemokine signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with SHC4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    ErbB signaling pathway SHC4; RAF1A; CAMK2B1; AREGB; RPS6KB2; MTOR; PLCG1; NCK2A; SHC2; AKT3A
    Ras signaling pathway FGF2; GNB3; RASA1; RHOA; GAB2; RALGDS; FIGF; FGF13; FGF7; SHC1
    Chemokine signaling pathway CCR1; Ccl12; CCL4L1; PIK3CD; PRKACG; GRK1; PRKCB; Ccl21a; CCR7; PIK3R3
    Phospholipase D signaling pathway PLD2; FYN; FCER1G; MS4A2; KIT; RHOA; PLD1; PLA2G4A; PLA2G4C; RAF1
    Focal adhesion IGF1; TNW; RAC3B; GRB2A; PTK2AA; HGF; PTENB; COL5A2A; RAC2; PDGFRB
    Natural killer cell mediated cytotoxicity IFNA14; KLRD1; HLA-A; SH3BP2; GRB2; PPP3R1; PIK3CB; HRAS; KLRC2; PAK1
    Neurotrophin signaling pathway MAP2K5; BAX; CAMK2D; RELA; TRP53; MAPK7; TRAF6; CALML5; Fasl; MATK
    Insulin signaling pathway PRKCI; CALM4; FLOT1; ARAF; EIF4E2RS1; SLC2A4; EIF4EA; PRKAA2; RAF1A; PTPRF
    Estrogen signaling pathway NRAS; MAPK3; PIK3R5; GNAQ; MAP2K2; SHC3; MAP2K1; CALM3; CALM4; KRAS
    Prolactin signaling pathway SOS1; STAT1; TH; SHC4; GRB2; ELF5; SLC2A2; PIK3CB; PIK3CA; LHB
    Alcoholism H2AFY2; PRKACA; GM14477; CREB3L1; HIST1H4B; CAMKK2; H2BFWT; HIST1H3I; GNG11; PKIA
    Bacterial invasion of epithelial cells CD2AP; SEPT2; WASF1; CTNNA2; CAV1; HCLS1; RHOA; CBL; VCL; PIK3CB
    MicroRNAs in cancer MDM4; CCND2; SOS1; PIM1; FGFR3; UBE2I; CDCA5; TNC; ZEB1; TTC6
    Chronic myeloid leukemia TGFBR1; MDM2; CRKL; CCND1; CBL; HDAC1; SHC1; TRP53; PIK3CB; BRAF

    SHC4 has several biochemical functions, for example, protein binding, protein domain specific binding, protein kinase binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SHC4 itself. We selected most functions SHC4 had, and list some proteins which have the same functions with SHC4. You can find most of the proteins on our site.

    Function Related Protein
    protein binding CST7; ZNF622; REEP5; MAGEB2; DDR2; RAB18; MYOC; PTRF; SMAD3B; UNC45A
    protein domain specific binding PRKAR2B; CALM3; STXBP1; EFS; MYO7A; THRA; WNT1; NEFL; PHRF1; HOMER3
    protein kinase binding CACNB4; PTPRJ; TSKS; HDAC7A; YWHAZ; XBP1; CNTLN; FAF1; CCNA2; SUFU
    receptor tyrosine kinase binding HYAL2; SQSTM1; PIK3R2; SHC3; LRP4; ANGPT2A; ANGPT4; PTPN11; FIZ1; ANGPT1

    SHC4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SHC4 here. Most of them are supplied by our site. Hope this information will be useful for your research of SHC4.


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