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Siah1a

Official Full Name

seven in absentia 1A

Species	Cat.#	Product name	Source (Host)	Tag	Price
Mouse	SIAH1A-15120M	Recombinant Mouse SIAH1A Protein	Mammalian Cell	His	Inquiry
Mouse	SIAH1A-8168M	Recombinant Mouse SIAH1A Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi	Inquiry
Mouse	SIAH1A-8168M-B	Recombinant Mouse SIAH1A Protein Pre-coupled Magnetic Beads	HEK293		Inquiry

Involved Pathway
Protein Function
Interacting Protein

Siah1a involved in several pathways and played different roles in them. We selected most pathways Siah1a participated on our site, such as p signaling pathway, Ubiquitin mediated proteolysis, Wnt signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with Siah1a were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
p signaling pathway	GADD45AA;CD82B;CD82A;GTSE1;CASP9;TSC2;CCNE2;SIAH2L;TP53AIP1
Ubiquitin mediated proteolysis	PIAS4;UBE2Q2;UBE2G1B;UBE2U;CDH1-A;UBA2;UBE2KA;UBA7;CDC26
Wnt signaling pathway	CTBP2A;LRP5;CUL1B;PLCB1;MAPK8;SMAD3;FBXW2;PPARD;DVL1B

Siah1a has several biochemical functions, for example, UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity, coenzyme F420-0 gamma-glutamyl ligase activity, coenzyme F420-2 alpha-glutamyl ligase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by Siah1a itself. We selected most functions Siah1a had, and list some proteins which have the same functions with Siah1a. You can find most of the proteins on our site.

Function	Related Protein
UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity	RC3H2;MGRN1A;HERC2;HECW2;RNF180;MARCH6;SHRPRBCK1R;TMEM129;LTN1
coenzyme F420-0 gamma-glutamyl ligase activity	LTN1;MARCH4;TRIM50;RNF187;HECW2;ITCHA;MARCH6;MYLIPB;UBR1
coenzyme F420-2 alpha-glutamyl ligase activity	TRIM71;ARIH1L;UBE2IA;ITCHA;RNF187;ZNRF3;LTN1;TRIM41;RC3H2
identical protein binding	VAMP2;LYZ2;SH2B2;MSANTD3;PAICS;PICK1;SNCAIP;SOX10;S100B
ligase activity	UBR5;RNF181;ACSM2;HERC5;RCHY1;TRIM23;MGRN1;CDC34A;PET112L
metal ion binding	ZNF280D;ZBTB7B;GFI1B;JUB;ZNF471;KCNIP3A;NUDT11;DTD1;ZNF781
protein C-terminus binding	VGLL3;SDCBP2;NPAT;IFT52;PEX12;FOXN3;MAP3K7;HAND2;BCL10
protein binding	FANCA;HORMAD1;UQCC2;TOPORS;PRKCE;ZBTB2;ENTPD3;NRIP2;EEF1E1
protein homodimerization activity	IZUMO3;SYNE1;CECR1;MGST1;RRAGA;SLC39A13;TIRAP;TPD52;ALDH5A1
protein-glutamic acid ligase activity	MYLIPB;UBE2IB;RAG1;RNF144AB;HERC2;MUL1A;TRIM50;MARCH6;MGRN1A
protein-glycine ligase activity	ZNRF2B;SIAH1A;TTLL3;MARCH4;RC3H2;NEURL3;ARIH1L;MUL1A;MGRN1A
protein-glycine ligase activity, elongating	MUL1A;RNF144AA;SHRPRBCK1R;TRIM50;UBR1;TRIM71;MARCH11;RC3H2;RNF187
protein-glycine ligase activity, initiating	ITCHA;RNF144AA;RNF149;MARCH6;UBE2IB;SIAH1A;TRIM50;NEURL1B;RNF169
ribosomal S6-glutamic acid ligase activity	RFWD2;RNF144AB;RNF169;SIAH1A;TRIM50;HERC2;RNF144AA;RAG1;LTN1
tubulin-glutamic acid ligase activity	RNF169;ZNRF2B;MGRN1A;RNF149;TRIM50;RNF144AB;UBE2IB;MYLIPB;ARIH1L
tubulin-glycine ligase activity	DTX1;UBR1;MGRN1A;TRIM50;UBE2IA;RNF187;LTN1;UBE2IB;RAG1
ubiquitin protein ligase activity	UBE3A;RNF126;UBE2KA;RNF34;RNF14;RNF19B;RNF144B;RNF220;RNF121
ubiquitin-protein transferase activity	XIAP;FLJ11011L;WWP2;BTR22;ANKIB1A;UBA7;RNF220;RNF25;UBE2L6
zinc ion binding	PDXK;UQCRC2A;TRIM2A;ADAMTS2;PXN;PCGF5;ZADH2;RUNX1;MKRN1

Siah1a has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Siah1a here. Most of them are supplied by our site. Hope this information will be useful for your research of Siah1a.

Dab1; Sh3rf1; AGAP2