Siah1a
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Official Full Name
seven in absentia 1A
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| SIAH1A-15120M | Recombinant Mouse SIAH1A Protein | Mammalian Cells | Mouse | His |
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| SIAH1A-8168M | Recombinant Mouse SIAH1A Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | Avi&Fc&His |
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| SIAH1A-8168M-B | Recombinant Mouse SIAH1A Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
Siah1a involved in several pathways and played different roles in them. We selected most pathways Siah1a participated on our site, such as p signaling pathway,Ubiquitin mediated proteolysis,Wnt signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with Siah1a were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Wnt signaling pathway | TCF7L2,SMAD4,WNT11R,EP300,WNT2BB,FOSL1A,CUL1B,SIAH1,PLCB2,TP53 |
| Ubiquitin mediated proteolysis | KLHL9,HERC4,PIAS4,UBE4B,CDC20,HERC2,CUL4A,ITCH,WWP2,ITCHA |
| p signaling pathway | SIAH1,CCNB2,Casp3,SESN1,CYCS,SHISA5,MDM4,CD82A,TP53I3,TRP53 |
Protein Function
Siah1a has several biochemical functions, for example, UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity,coenzyme F420-0 gamma-glutamyl ligase activity,coenzyme F420-2 alpha-glutamyl ligase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by Siah1a itself. We selected most functions Siah1a had, and list some proteins which have the same functions with Siah1a. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| coenzyme F420-0 gamma-glutamyl ligase activity | MARCH5L,NEURL3,MYLIPA,MUL1A,TMEM129,MGRN1A,ARIH1L,RNF149,MARCH9,HECW2 |
| ubiquitin protein ligase activity | ZNRF2,COP1,FLJ11011L,RNF222,C18orf25,RBBP6,RNF4,HECW2,NEURL3,AMFR |
| ligase activity | RNF6,CDC34B,TNFAIP3,TRAF7,ACSL1,TRAIP,RNF146,RNF180,PDZRN3,MUL1A |
| zinc ion binding | ZNRF4,ZDHHC9,RORB,ZFAND1,OTUD7A,CA12,DNMT5,KDM7AB,RBM4B,NR6A1A |
| ubiquitin-protein transferase activity | XIAP,RNF25,FBXO11,FBXO25,UBE2D3,RNF144AB,RC3H2,TTC3,SHPRH,FBXO3 |
| protein-glycine ligase activity, elongating | TRIM71,RNF169,RC3H2,MARCH6,RAG1,UBE2IA,RNF144AB,G2E3,ZNRF2B,UBR1 |
| tubulin-glycine ligase activity | HERC2,UBE2IB,ARIH1L,TRIM50,RC3H2,ITCHA,RNF180,RNF169,LTN1,FLR |
| protein-glycine ligase activity, initiating | ARIH1L,TTLL3,MARCH6,LTN1,MGRN1A,RNF169,MARCH11,MARCH4,SIAH2L,RNF149 |
| coenzyme F420-2 alpha-glutamyl ligase activity | LTN1,RNF187,HECW2,UBE2IB,MARCH5L,TRIM71,MGRN1A,ZNRF2B,MARCH4,TRIM50 |
Interacting Protein
Siah1a has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Siah1a here. Most of them are supplied by our site. Hope this information will be useful for your research of Siah1a.
Dab1;Sh3rf1;AGAP2
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