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SLCO1B3

  • Official Full Name

    solute carrier organic anion transporter family, member 1B3

  • Overview

    This gene encodes a liver-specific member of the organic anion transporter family. The encoded protein is a;transmembrane receptor that mediates the sodium-independent uptake of endogenous and xenobiotic compounds and plays a;critical role in bile acid and bilirubin transport. Mutations in this gene are a cause of Rotor type;hyperbilirubinemia.
  • Synonyms

    SLCO1B3; solute carrier organic anion transporter family, member 1B3; SLC21A8, solute carrier family 21 (organic anion transporter), member 8; solute carrier organic anion transporter family member 1B3; OATP1B3; OATP8; organic anion transporter 8; organi;

  • Cell & Tissue Lysates
  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Cynomolgus Monkey
  • Human
  • Rat
  • Rhesus Macaque
  • HEK293
  • Mammalian Cell
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human SLCO1B3-1688HCL Recombinant Human SLCO1B3 293 Cell Lysate HEK293 N/A
Rat SLCO1B3-5595R Recombinant Rat SLCO1B3 Protein Mammalian Cell His
Rat SLCO1B3-5254R Recombinant Rat SLCO1B3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat SLCO1B3-5254R-B Recombinant Rat SLCO1B3 Protein Pre-coupled Magnetic Beads HEK293
Cynomolgus Monkey SLCO1B3-941C Recombinant Cynomolgus SLCO1B3 Protein, His-tagged Mammalian Cell His
Cynomolgus Monkey SLCO1B3-684C-B Recombinant Cynomolgus Monkey SLCO1B3 Protein Pre-coupled Magnetic Beads HEK293
Cynomolgus Monkey SLCO1B3-684C Recombinant Cynomolgus Monkey SLCO1B3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque SLCO1B3-4319R Recombinant Rhesus monkey SLCO1B3 Protein, His-tagged Mammalian Cell His
Rhesus Macaque SLCO1B3-4135R Recombinant Rhesus Macaque SLCO1B3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque SLCO1B3-4135R-B Recombinant Rhesus Macaque SLCO1B3 Protein Pre-coupled Magnetic Beads HEK293
  • Involved Pathway
  • Protein Function
  • Interacting Protein

SLCO1B3 involved in several pathways and played different roles in them. We selected most pathways SLCO1B3 participated on our site, such as Bile secretion, which may be useful for your reference. Also, other proteins which involved in the same pathway with SLCO1B3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Bile secretionAQP9;SLC4A4;SLC51B;ABCG2;PRKACA;SLC22A7;FXYD2;ATP1B4;SLCO1B3

SLCO1B3 has several biochemical functions, for example, bile acid transmembrane transporter activity, organic anion transmembrane transporter activity, sodium-independent organic anion transmembrane transporter activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SLCO1B3 itself. We selected most functions SLCO1B3 had, and list some proteins which have the same functions with SLCO1B3. You can find most of the proteins on our site.

Function Related Protein
bile acid transmembrane transporter activitySLCO1C1;SLCO1A6;SLCO1A2;SLCO1F3;SLCO1F4;SLCO1A4;SLCO1B1;SLCO1B2;SLCO1D1
organic anion transmembrane transporter activitySLC17A3;ABCC2;SLCO1B3;SLCO1A5;SLC22A20;SLC22A17;SLC22A23;SLCO1D1;SLCO1A4
sodium-independent organic anion transmembrane transporter activitySLC22A6;SLCO1B1;SLCO1A2;SLCO1F2;SLCO1C1;SLCO1F1;SLC22A12;SLCO3A1;SLCO2A1

SLCO1B3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SLCO1B3 here. Most of them are supplied by our site. Hope this information will be useful for your research of SLCO1B3.

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