SMAD9

  • Official Full Name

    SMAD family member 9

  • Overview

    The protein encoded by this gene is a member of the SMAD family, which transduces signals from TGF-beta family members. The encoded protein is activated by bone morphogenetic proteins and interacts with SMAD4. Two transcript variants encoding different isoforms have been found for this gene.
  • Synonyms

    SMAD9; SMAD family member 9; MAD, mothers against decapentaplegic homolog 9 (Drosophila) , MADH6, MADH9, SMAD, mothers against DPP homolog 9 (Drosophila); mothers against decapentaplegic homolog 9; MAD homolog 9; MADH6; Mothers against decapentaplegic; SMAD 9; SMAD, mothers against DPP homolog 9 (Drosophila); SMAD8A; SMAD8B; SMAD, mothers against DPP homolog 9; Mothers against decapentaplegic, drosophila, homolog of, 9; MADH9; SMAD8;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rat
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • Mammalian Cell
  • GST
  • His
  • His (Fc)
  • Avi
  • His|GST
  • Myc
  • DDK
  • Myc|DDK
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human SMAD9-2802H Recombinant Human SMAD9, GST-tagged E.coli GST
Human SMAD9-234H Recombinant Human SMAD9, GST-tagged E.coli GST
Human SMAD9-1645HCL Recombinant Human SMAD9 cell lysate N/A
Human SMAD9-302H Recombinant Human SMAD9 Protein, His/GST-tagged E.coli His/GST
Human SMAD9-1914H Recombinant Human SMAD9 Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human SMAD9-5872H Recombinant Human SMAD9 Protein (Thr226-Pro459), N-GST tagged E.coli N-GST
Human SMAD9-098H Recombinant Human SMAD9 Protein, His-tagged E.coli His
Mouse Smad9-5955M Recombinant Mouse Smad9 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Rat SMAD9-5611R Recombinant Rat SMAD9 Protein Mammalian Cell His
Rat SMAD9-5270R Recombinant Rat SMAD9 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat SMAD9-5270R-B Recombinant Rat SMAD9 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque SMAD9-4334R Recombinant Rhesus monkey SMAD9 Protein, His-tagged Mammalian Cell His
Rhesus Macaque SMAD9-4150R-B Recombinant Rhesus Macaque SMAD9 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque SMAD9-4150R Recombinant Rhesus Macaque SMAD9 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Zebrafish SMAD9-1212Z Recombinant Zebrafish SMAD9 Mammalian Cell His
Chicken SMAD9-2196C Recombinant Chicken SMAD9 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • SMAD9 Related Gene Family
  • SMAD9 Related Research Area
  • SMAD9 Related Signal Pathway

SMAD9 involved in several pathways and played different roles in them. We selected most pathways SMAD9 participated on our site, such as TGF-beta signaling pathway, Signaling pathways regulating pluripotency of stem cells, which may be useful for your reference. Also, other proteins which involved in the same pathway with SMAD9 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
TGF-beta signaling pathwayTGIF1;ID4;TGFB3;GDF6;RBL1;CHRD;INHBC;BMPR1A;BMPR1B
Signaling pathways regulating pluripotency of stem cellsACVR1B;TBX3;ESRRB;NODAL;ONECUT1;PIK3R2;WNT1;BMP2;JARID2

SMAD9 has several biochemical functions, for example, DNA binding, metal ion binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SMAD9 itself. We selected most functions SMAD9 had, and list some proteins which have the same functions with SMAD9. You can find most of the proteins on our site.

Function Related Protein
DNA bindingPOLR3F;FOXA1;MYCLB;TCF4;C1D;HLFA;HOXC4A;PAX2;GTF2IRD2
metal ion bindingKDM6BB;BCL11BA;ZNF576.2;ENPP4;SP5;ATP2C1;ZNF43;ZNF468;ZFP768
protein bindingFCRL4;ARSI;HER5;EXOC3L;HBZ;PRICKLE1;CD300LD;COL17A1;GJA4
transcription factor activity, sequence-specific DNA bindingGRHL2;ZFP639;CBFB;XBP1;ZFP110;IRF6;WNT5A;HEYL;SOLH
transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activitySMAD1;SMAD9;SMAD2;SMAD3

SMAD9 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SMAD9 here. Most of them are supplied by our site. Hope this information will be useful for your research of SMAD9.

KDM1A; PRMT6; UBA6; MTMR11; EIF3F; PIR; KMT2D; KDM6A; ZEB2; MCM3AP; MAN1A2; LRP5; SF3B1; DKK1; AP2A1; CSH1; FTL; CYP11A1

TGF
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