SMAD9

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SMAD9

Official Full Name SMAD family member 9
Background The protein encoded by this gene is a member of the SMAD family, which transduces signals from TGF-beta family members. The encoded protein is activated by bone morphogenetic proteins and interacts with SMAD4. Two transcript variants encoding different isoforms have been found for this gene.
Synonyms SMAD9; SMAD family member 9; MAD, mothers against decapentaplegic homolog 9 (Drosophila) , MADH6, MADH9, SMAD, mothers against DPP homolog 9 (Drosophila); mothers against decapentaplegic homolog 9; MAD homolog 9; MADH6; Mothers against decapentaplegic; SMAD 9; SMAD, mothers against DPP homolog 9 (Drosophila); SMAD8A; SMAD8B; SMAD, mothers against DPP homolog 9; Mothers against decapentaplegic, drosophila, homolog of, 9; MADH9; SMAD8
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rat
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Tag :
    • GST
    • His
    • Myc/DDK
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human SMAD9-1645HCL Recombinant Human SMAD9 cell lysate N/A
    Human SMAD9-1914H Recombinant Human SMAD9 Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human SMAD9-234H Recombinant Human SMAD9, GST-tagged E.coli GST
    Human SMAD9-2802H Recombinant Human SMAD9, GST-tagged E.coli GST
    Human SMAD9-302H Recombinant Human SMAD9 Protein, His/GST-tagged E.coli His/GST
    Mouse Smad9-5955M Recombinant Mouse Smad9 Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Rat SMAD9-5611R Recombinant Rat SMAD9 Protein Mammalian Cell His
    Rhesus Macaque SMAD9-4334R Recombinant Rhesus monkey SMAD9 Protein, His-tagged Mammalian Cell His
    Chicken SMAD9-2196C Recombinant Chicken SMAD9 Mammalian Cell His
    Zebrafish SMAD9-1212Z Recombinant Zebrafish SMAD9 Mammalian Cell His

    SMAD9 involved in several pathways and played different roles in them. We selected most pathways SMAD9 participated on our site, such as TGF-beta signaling pathway, Signaling pathways regulating pluripotency of stem cells, which may be useful for your reference. Also, other proteins which involved in the same pathway with SMAD9 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    TGF-beta signaling pathway ACVR1C; ACVR2AA; MAPK1; RPS6KB1; INHBC; ID4; RHOAC; LFT2; NBL1; BMPR1B
    Signaling pathways regulating pluripotency of stem cells WNT1; LEFTY2; GSK3B; NODAL; MYF5; BMPR2; PIK3R5; PIK3R3; WNT3; INHBC

    SMAD9 has several biochemical functions, for example, DNA binding, metal ion binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SMAD9 itself. We selected most functions SMAD9 had, and list some proteins which have the same functions with SMAD9. You can find most of the proteins on our site.

    Function Related Protein
    DNA binding HIST2H2AA2; ETS1; ZC3H3; DBN1; NR1D2A; PAX7B; HDX; NCOR2; ZFY1; ZNF763
    metal ion binding ROR2; TREX1; GMEB2; ZKSCAN3; ZNF182; CHD4A; ZNF133; BLF; TRIM101; CSH2
    protein binding CHCHD3; ZNF263; SLC25A5; NLRC4; FKBP7; ATG101; FOXL2; GP6; CXCR2; C10orf33
    transcription factor activity, sequence-specific DNA binding TFAP2B; E2F6; NR5A5; DLX2; POU5F1; NFE2L1; NOTCH1; DMRTA1; ELK1; HMGA1A
    transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity SMAD1; SMAD3; SMAD2; SMAD9

    SMAD9 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SMAD9 here. Most of them are supplied by our site. Hope this information will be useful for your research of SMAD9.

    KDM1A; PRMT6; UBA6; MTMR11; EIF3F; PIR; KMT2D; KDM6A; ZEB2; MCM3AP; MAN1A2; LRP5; SF3B1; DKK1; AP2A1; CSH1; FTL; CYP11A1

    TGF

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