|Official Full Name||SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2|
|Background||The protein encoded by this gene is a member of the SWI/SNF family of proteins, whose members display helicase and ATPase activities and which are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI and contains a predicted leucine zipper motif typical of many transcription factors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]|
|Synonyms||SMARCC2; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2; Rsc8; BAF170; CRACC2; SWI/SNF complex subunit SMARCC2; SWI3-like protein; BRG1-associated factor 170; SWI/SNF complex 170 kDa subunit; chromatin remodeling complex BAF170 subunit; mammalian chromatin remodeling complex BRG1-associated factor 170; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2;|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
smarcc2 involved in several pathways and played different roles in them. We selected most pathways smarcc2 participated on our site, such as Chromatin modifying enzymes, Chromatin organization, Glucocorticoid receptor regulatory network, which may be useful for your reference. Also, other proteins which involved in the same pathway with smarcc2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Chromatin modifying enzymes||GATAD2A; CHD4A; MORF4L1; SMARCE1; ELP4; EED; VPS72; ARID1A; PRMT7; EPC1|
|Chromatin organization||PHF17; KDM5B; KIAA1267; KDM6AL; MORF4L1; SUZ12A; ELP3; DPY30; EPC1; GATAD2AB|
|Glucocorticoid receptor regulatory network||SMARCC2; CSN2; SMARCA4; BGLAP; KRT14; NR1I3; KRT5; POU2F1; EGR1; SMARCD1|
|Prostate Cancer||CCNE1; BAD; Ar; PIK3R5; ARAF; MAPK1; NDRG1; CCND1; EP300; FOXA1|
|RMTs methylate histone arginines||ARID2; SMARCA4; PRMT5; PBRM1; SMARCD1; SMARCC2; SMARCC1; SMARCA2; ACTL6B; SMARCC1B|
|TNF-alpha/NF-kB Signaling Pathway||COPS3; FAF1; TNIP1; ZFAND5; CRADD; USP2; NKIRAS1; PEG3; TRAIP; SMARCE1|
smarcc2 has several biochemical functions, for example, contributes_to RNA polymerase II core promoter proximal region sequence-specific DNA binding, contributes_to RNA polymerase II distal enhancer sequence-specific DNA binding, contributes_to nucleosomal DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by smarcc2 itself. We selected most functions smarcc2 had, and list some proteins which have the same functions with smarcc2. You can find most of the proteins on our site.
|contributes_to RNA polymerase II core promoter proximal region sequence-specific DNA binding||SMARCC1; MTA2; CHD4; HDAC1; SMARCA4; SMARCE1; GATAD2B; RBBP4; MBD3; HDAC2|
|contributes_to RNA polymerase II distal enhancer sequence-specific DNA binding||CHD4; GATAD2B; SMARCE1; RBBP4; SMARCC1; HDAC1; MBD3; SMARCB1; SMARCC2; HDAC2|
|contributes_to nucleosomal DNA binding||HDAC1; SMARCC1; MBD3; SMARCB1; SMARCC2; GATAD2B; ACTB; HDAC2; MTA2; ACTL6A|
|protein binding||CNOT6L; PEX10; MBD4; CCDC103; KAZN; FTL; PPP1R2P3; GNPDA2; GAST; U2AF2|
|transcription coactivator activity||NR2C2; HIF3A; NCOA1; KAT5; COPS5; TFDP1A; RNF14; MED17; RUNX1; NFYC|
smarcc2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with smarcc2 here. Most of them are supplied by our site. Hope this information will be useful for your research of smarcc2.