SNX14 Protein

SNX14

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SNX14

Official Full Name sorting nexin 14
Background This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. The encoded protein also contains a regulator of G protein signaling (RGS) domain. Regulator of G protein signaling family members are regulatory molecules that act as GTPase activating proteins for G alpha subunits of heterotrimeric G proteins. Two transcript variants encoding distinct isoforms have been identified for this gene.
Synonyms SNX14; sorting nexin 14; sorting nexin-14; RGS PX2; MGC13217; RGS-PX2; RP11-321N4.2; SNX14_HUMAN; OTTHUMP00000016812; OTTHUMP00000016813; OTTHUMP00000220929; OTTHUMP00000220930; OTTHUMP00000220931; OTTHUMP00000220932
    • Species :
    • Chicken
    • Human
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • E.coli
    • Mammalian Cell
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human SNX14-1659HCL Recombinant Human SNX14 cell lysate N/A
    Human SNX14-2856H Recombinant Human SNX14, GST-tagged E.coli GST
    Rhesus Macaque SNX14-4390R Recombinant Rhesus monkey SNX14 Protein, His-tagged Mammalian Cell His
    Chicken SNX14-3350C Recombinant Chicken SNX14 Mammalian Cell His
    Zebrafish SNX14-3933Z Recombinant Zebrafish SNX14 Mammalian Cell His

    SNX14 involved in several pathways and played different roles in them. We selected most pathways SNX14 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with SNX14 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    SNX14 has several biochemical functions, for example, phosphatidylinositol-3,5-bisphosphate binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SNX14 itself. We selected most functions SNX14 had, and list some proteins which have the same functions with SNX14. You can find most of the proteins on our site.

    Function Related Protein
    phosphatidylinositol-3,5-bisphosphate binding WDR45B; WDR45L; MAPKAP1; WIPI2; D6WSU116E; SESTD1; SH3PXD2B; WDR45; JPH2; GBF1

    SNX14 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SNX14 here. Most of them are supplied by our site. Hope this information will be useful for your research of SNX14.

    q99ib8-pro_0000045601; pi3p

    Thomas, AC; Williams, H; et al. Mutations in SNX14 Cause a Distinctive Autosomal-Recessive Cerebellar Ataxia and Intellectual Disability Syndrome. AMERICAN JOURNAL OF HUMAN GENETICS 95:611-621(2014).
    Huang, HS; Yoon, BJ; et al. Snx14 Regulates Neuronal Excitability, Promotes Synaptic Transmission, and Is Imprinted in the Brain of Mice. PLOS ONE 9:-(2014).

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