SNX18
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Official Full Name
sorting nexin 18 -
Overview
This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein does not contain a coiled coil region, like some family members, but contains a SH3 domain. Multiple transcript variants encoding different isoforms have been found for this gene. -
Synonyms
SNX18;sorting nexin 18;SNAG1, sorting nexin associated golgi protein 1;sorting nexin-18;SH3PX2;SH3PXD3B;SH3 and PX domain-containing protein 3B;sorting nexin associated golgi protein 1;sorting nexin-associated Golgi protein 1;SNAG1;FLJ11997;FL
Recombinant Proteins
- Human
- Rhesus macaque
- Mouse
- E.coli
- Mammalian Cells
- HEK293
- His
- T7
- Non
- Flag
- Avi
- Fc
- DDK
- Myc
Involved Pathway
SNX18 involved in several pathways and played different roles in them. We selected most pathways SNX18 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with SNX18 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
SNX18 has several biochemical functions, for example, phosphatidylinositol-4,5-bisphosphate binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SNX18 itself. We selected most functions SNX18 had, and list some proteins which have the same functions with SNX18. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | BCAM,PTGES2,SMC1A,TXN2,CDKN2A,SMAD7,CARS,C9orf78,ZNF550,NOTCH3 |
| phosphatidylinositol-4,5-bisphosphate binding | TIRAP,ADAP2,SYTL2,FAM123A,RAB35,TWF1,PLCB1,VIL1,PHLDA3,KCNJ2 |
Interacting Protein
SNX18 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SNX18 here. Most of them are supplied by our site. Hope this information will be useful for your research of SNX18.
RAB11FIP5;ANKRD28;FASLG;SOS1;SOS2;ITCH;SNX9;SNX8
Resources
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References
- Willenborg, C; Jing, J; et al. Interaction between FIP5 and SNX18 regulates epithelial lumen formation. JOURNAL OF CELL BIOLOGY 195:71-86(2011).
- Nakazawa, S; Gotoh, N; et al. Expression of Sorting Nexin 18 (SNX18) Is Dynamically Regulated in Developing Spinal Motor Neurons. JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY 59:202-213(2011).
