SNX21

Official Full Name

sorting nexin family member 21
Overview

This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein does not contain a coiled coil region, like some family members. The specific function of this protein has not been determined. Multiple transcript variants encoding distinct isoforms have been identified for this gene.
Synonyms

SNX21; sorting nexin family member 21; C20orf161, chromosome 20 open reading frame 161; sorting nexin-21; dJ337O18.4; SNX L; C20orf161; SNXL; Sorting nexin 21; Sorting nexin L; SNX-L; PP3993;

Species	Cat.#	Product name	Source (Host)	Tag	Price
Human	SNX21-1593HCL	Recombinant Human SNX21 293 Cell Lysate	HEK293	Non	Inquiry
Mouse	Snx21-171M	Recombinant Mouse Snx21 Protein, MYC/DDK-tagged	HEK293T	Myc&DDK	Inquiry
Zebrafish	SNX21-4702Z	Recombinant Zebrafish SNX21	Mammalian Cell	His	Inquiry

Involved Pathway
Protein Function
Interacting Protein
Other Resource

SNX21 involved in several pathways and played different roles in them. We selected most pathways SNX21 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with SNX21 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

SNX21 has several biochemical functions, for example, phosphatidylinositol-3-phosphate binding, phosphatidylinositol-4,5-bisphosphate binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SNX21 itself. We selected most functions SNX21 had, and list some proteins which have the same functions with SNX21. You can find most of the proteins on our site.

Function	Related Protein
phosphatidylinositol-3-phosphate binding	FAM21C;SNX21;SH3PXD2B;VPS36;RS1;SNX13;SNX3;ZFYVE28;WIPI2
phosphatidylinositol-4,5-bisphosphate binding	PARD3;VIL1;STXBP6;AMER2;PHLDA3;SCIN;TULP3;CCDC167;SNX21

SNX21 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SNX21 here. Most of them are supplied by our site. Hope this information will be useful for your research of SNX21.

LRRK1; COX6A2

Research Area

Kleino, I; Ortiz, RM; et al. Alternative Splicing of ADAM15 Regulates its Interactions With Cellular SH3 Proteins. JOURNAL OF CELLULAR BIOCHEMISTRY 108:877-885(2009).