SOCS5

  • Official Full Name

    suppressor of cytokine signaling 5

  • Overview

    The protein encoded by this gene contains a SH2 domain and a SOCS BOX domain. The protein thus belongs to the suppressor of cytokine signaling (SOCS) family, also known as STAT-induced STAT inhibitor (SSI) protein family. SOCS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The specific function of this protein has not yet been determined. Two alternatively spliced transcript variants encoding an identical protein have been reported.
  • Synonyms

    SOCS5; suppressor of cytokine signaling 5; CIS6; Cish5; CISH6; KIAA0671; SOCS 5; CIS-6; cytokine-inducible SH2 protein 6; cytokine-inducible SH2-containing protein 5; SOCS-5;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rhesus Macaque
  • E.coli
  • HEK293
  • Mammalian Cell
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human SOCS5-552H Recombinant Human SOCS5 Protein, His-tagged E.coli His
Human SOCS5-1579HCL Recombinant Human SOCS5 293 Cell Lysate HEK293 N/A
Human SOCS5-1578HCL Recombinant Human SOCS5 293 Cell Lysate HEK293 N/A
Mouse SOCS5-15746M Recombinant Mouse SOCS5 Protein Mammalian Cell His
Mouse SOCS5-8565M Recombinant Mouse SOCS5 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse SOCS5-8565M-B Recombinant Mouse SOCS5 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque SOCS5-4404R Recombinant Rhesus monkey SOCS5 Protein, His-tagged Mammalian Cell His
Rhesus Macaque SOCS5-4220R Recombinant Rhesus Macaque SOCS5 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque SOCS5-4220R-B Recombinant Rhesus Macaque SOCS5 Protein Pre-coupled Magnetic Beads HEK293
Chicken SOCS5-3841C Recombinant Chicken SOCS5 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Other Resource
  • SOCS5 Related Signal Pathway

SOCS5 involved in several pathways and played different roles in them. We selected most pathways SOCS5 participated on our site, such as Jak-STAT signaling pathway, Prolactin signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with SOCS5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Jak-STAT signaling pathwayIL27RA;BCL2;PTPN2A;MTOR;PTPN2B;SOCS2;IL11RA;CTF1;IFNA2
Prolactin signaling pathwayINS1;TNFRSF11A;STAT5B;SOCS4;MAPK3;SRC;KRAS;SOCS6;FOXO3

SOCS5 has several biochemical functions, for example, epidermal growth factor receptor binding, protein binding, receptor tyrosine kinase binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SOCS5 itself. We selected most functions SOCS5 had, and list some proteins which have the same functions with SOCS5. You can find most of the proteins on our site.

Function Related Protein
epidermal growth factor receptor bindingHBEGF;EGF;Fert2;LINGO1;SHC1;ATXN2;TNK2;MS4A1;PLSCR1
protein bindingMRPL41;DCTN3;GCHFR;TRIM2;GSPT2;ZBTB22;NFU1;C14orf93;EFHA1
receptor tyrosine kinase bindingSHC4;FLT3LG;PTPN1;TOB1;LRP4;ANGPT1;Flt3l;PTPN14;PLCG1

SOCS5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SOCS5 here. Most of them are supplied by our site. Hope this information will be useful for your research of SOCS5.

MET; KIT; PPP5C; CASP3; TCEB1; TMBIM1; npm_alk

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