SOX5

  • Official Full Name

    SRY (sex determining region Y)-box 5

  • Overview

    This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. The encoded protein may play a role in chondrogenesis. A pseudogene of this gene is located on chromosome 8. Multiple transcript variants encoding distinct isoforms have been identified for this gene.
  • Synonyms

    SOX5; SRY (sex determining region Y)-box 5; transcription factor SOX-5; L SOX5; MGC35153; Sex determining region Y box 5; SOX 5; SOX 5 protein; SOX5 protein; SOX5_HUMAN; SRY (sex determining region Y) box 5; SRY box 5; Transcription factor SOX 5; Transcription factor SOX5; OTTHUMP00000239955; OTTHUMP00000239958; OTTHUMP00000239959; OTTHUMP00000239960; OTTHUMP00000239961; OTTHUMP00000239962; OTTHUMP00000239963; L-SOX5;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Chicken
  • Human
  • Mouse
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • Mammalian Cell
  • Sf9 Insect Cell
  • DDK
  • His
  • Myc
  • N/A
  • N
  • T7|His
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human SOX5-143H Recombinant Human SOX5 protein, T7/His-tagged E.coli T7/His
Human SOX5-2884H Recombinant Human SOX5, His-tagged E.coli His
Human SOX5-30693TH Recombinant Human SOX5, His-tagged E.coli His
Human SOX5-107H Recombinant Human SOX5 Protein, DDK-tagged Sf9 Insect Cell DDK
Human SOX5-1558HCL Recombinant Human SOX5 293 Cell Lysate HEK293 N/A
Human SOX5-659H Recombinant Human SOX5 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human SOX5-6337H Recombinant Human SOX5 Protein (Met14-Pro284), N-His tagged E.coli N-His
Human SOX5-2720H Recombinant Human SOX5 Protein, His-tagged E.coli N-His
Mouse Sox5-6057M Recombinant Mouse Sox5 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Zebrafish SOX5-3397Z Recombinant Zebrafish SOX5 Mammalian Cell His
Chicken SOX5-1204C Recombinant Chicken SOX5 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • SOX5 Related Research Area

SOX5 involved in several pathways and played different roles in them. We selected most pathways SOX5 participated on our site, such as Endochondral Ossification, Neural Crest Differentiation, which may be useful for your reference. Also, other proteins which involved in the same pathway with SOX5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Endochondral OssificationRUNX2A;NKX3-2;MMP13;PTHLH;CDKN1C;DDR2;COL2A1;SOX6;MGP
Neural Crest DifferentiationDCT;SOX5;OLIG1;ASCL1;PMP22;TFAP2A;TBX6;TFAP2B;MYB

SOX5 has several biochemical functions, for example, RNA polymerase II transcription factor activity, sequence-specific DNA binding, protein binding, protein heterodimerization activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SOX5 itself. We selected most functions SOX5 had, and list some proteins which have the same functions with SOX5. You can find most of the proteins on our site.

Function Related Protein
RNA polymerase II transcription factor activity, sequence-specific DNA bindingZNF174;HIF1AL2;SP2;FOXH1;XBP1;SPI1;TFAP2E;FOXQ1;SOX9A
protein bindingDDB2;RAB2A;TNIK;BOP1;CAMP;CDK20;GALR2;SLC8A1;SEPT3
protein heterodimerization activityIKBKB;UBXN6;BCL2L10;TYRP1;UNC13A;EFHA1;IRAK3;SOX5;HIST3H2A
transcription factor activity, sequence-specific DNA bindingPHF5A;IKZF4;JUNBA;SUPT4H1;CREBL2;TRP53;LEF1;ELF2A;UBN1
transcription regulatory region DNA bindingSMAD7;THRA;BCL11AA;SALL1;TFAP4;CITED1;SALL4;SOX2;YY1

SOX5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SOX5 here. Most of them are supplied by our site. Hope this information will be useful for your research of SOX5.

ARID5A; g2xkq0_human; CRX; tax; LMO2; LMO1; PRR20C

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