SOX7
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Official Full Name
SRY (sex determining region Y)-box 7
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Overview
This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. The protein may play a role in tumorigenesis. A similar protein in mice is involved in the regulation of the wingless-type MMTV integration site family (Wnt) pathway. [provided by RefSeq, Jul 2008] -
Synonyms
SOX7; SRY (sex determining region Y)-box 7; transcription factor SOX-7;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- Zebrafish
- E.coli
- HEK293
- Mammalian Cell
- His
- Fc
- Avi
- T7
- Non
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Human | SOX7-173H | Recombinant Human SOX7 protein, T7/His-tagged | E.coli | His&T7 |
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| Human | SOX7-294H | Recombinant Human SOX7 Protein, His-tagged | E.coli | His |
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| Human | SOX7-1556HCL | Recombinant Human SOX7 293 Cell Lysate | HEK293 | Non |
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| Human | SOX7-2722H | Recombinant Human SOX7 Protein, His-tagged | E.coli | His | Gln217-Ser388 |
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| Mouse | SOX7-15786M | Recombinant Mouse SOX7 Protein | Mammalian Cell | His |
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| Mouse | SOX7-8593M | Recombinant Mouse SOX7 Protein, His (Fc)-Avi-tagged | HEK293 | His&Fc&Avi |
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| Mouse | SOX7-8593M-B | Recombinant Mouse SOX7 Protein Pre-coupled Magnetic Beads | HEK293 |
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| Zebrafish | SOX7-5171Z | Recombinant Zebrafish SOX7 | Mammalian Cell | His |
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- Involved Pathway
- Protein Function
- Interacting Protein
- Other Resource
SOX7 involved in several pathways and played different roles in them. We selected most pathways SOX7 participated on our site, such as Deactivation of the beta-catenin transactivating complex, Signal Transduction, Signaling by Wnt, which may be useful for your reference. Also, other proteins which involved in the same pathway with SOX7 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Deactivation of the beta-catenin transactivating complex | SRY;CTBP1;CBY1;SOX9A;PYGO1;TLE3;SOX9B;BCL9L;SOX13 |
| Signal Transduction | NEDD8;PRICKLE1;RYK;UTS2D;AKR1C21;MDK;S1PR3;LPAR5A;STRA6 |
| Signaling by Wnt | KREMEN1;LGR6;RNF146;PYGO2;LGR4;RBBP5;RNF43;RSPO3;WNT8-2 |
| TCF dependent signaling in response to WNT | WIF1;RSPO2;SOX4B;ASH2L;LGR4;SOX9B;TLE3B;LGR5;DACT1 |
SOX7 has several biochemical functions, for example, protein binding, sequence-specific DNA binding, transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SOX7 itself. We selected most functions SOX7 had, and list some proteins which have the same functions with SOX7. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | DIXDC1;MT1H;TGFBR1;C16orf53;LGALS14;CALM1;SELP;CHRDL2;FAM49B |
| sequence-specific DNA binding | RX2;FOXA;HOXB7A;TFAP4;FOXO3;GATA2B;NR2E3;TBX5;LHX2B |
| transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding | THRA;TEAD2;JUN;SOX9;HNF4A;GTF2IRD1;PURA;OLIG2;POU3F1 |
| transcription factor activity, sequence-specific DNA binding | GBX2;KLF7;BRD8;SALL3B;ZNF606;UBP1;ATF4B1;DMRT1;PCGF6 |
| transcription regulatory region DNA binding | SALL3B;ZFP513;RELA;TOMM20A;AHR;GATA4;ZFP746;REST;MESP1 |
SOX7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SOX7 here. Most of them are supplied by our site. Hope this information will be useful for your research of SOX7.
GLRX3; Dlg4; SMAD7; SMAD5
Research Area
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