Spna2
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Official Full Name
spectrin alpha 2 -
Synonyms
SPNA2;spectrin alpha 2;ENSMUSG00000057738;Spna-2;Sptan1;2610027H02Rik;2 B;2 18.0 cM;spectrin alpha chain, brain;spectrin alpha chain, brain;alpha-fodrin;alpha-II spectrin;fodrin alpha chain;alpha-spectrin 2, brain;spectrin, non-erythroid alpha chain
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| SPNA2-5689Z | Recombinant Zebrafish SPNA2 | Mammalian Cells | Zebrafish | His |
|
Involved Pathway
Spna2 involved in several pathways and played different roles in them. We selected most pathways Spna2 participated on our site, such as ARMS-mediated activation,Apoptosis,Apoptotic cleavage of cellular proteins, which may be useful for your reference. Also, other proteins which involved in the same pathway with Spna2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Caspase-mediated cleavage of cytoskeletal proteins | DBNL,CASP6L1,CASP6L2,PLEC,PLECA,DBNLA,VIML,DBNLB,GAS2,ADD1 |
| Apoptotic cleavage of cellular proteins | DBNLA,CASP6L2,DSG2,PLECA,BCAP31,STK26,SATB1,OCLN,DSG3,CLSPN |
| DAP12 interactions | SPTBN1,KIR2DS2,SPRED1,PAQR3A,JAK1,FRS2,KBTBD7,NRG4,DUSP6,SPTB |
| ARMS-mediated activation | SPTB,FRS2A,PSMD14,SPRED2,JAK3,DUSP1,CRK,PTPRA,DAB2IPB,DUSP4 |
| Apoptotic execution phase | CLSPN,HIST1H1E,PKP1,BMX,DBNL,CASP8L1,PLEC,HIST1H1D,DSG2,PANK1A |
| Cytokine Signaling in Immune system | LAMTOR2,FGF20A,TRIM10,IRF9,NRG3,RASGRP1,LGALS9,HAVCR2,PAQR3B,GBP4 |
| Apoptosis | TRAF2,CASP10,CASP6L2,NFKBIAB,AKT3A,BAXA,AKT1,PRKACB,HMGB2,TNFRSF1A |
| Axon guidance | CSF2RB,SLC14A2,PAK6,GNAI1,ITSN1,SLIT2,UNC5C,DLG3,COL4A4,EFNA1A |
Protein Function
Spna2 has several biochemical functions, for example, calcium ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by Spna2 itself. We selected most functions Spna2 had, and list some proteins which have the same functions with Spna2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| calcium ion binding | EHD3,CPNE1,S100A10A,CHP,FLG,PCDH10B,CDH12A,CANT1A,ATP2A1,PLCD1B |
Interacting Protein
Spna2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Spna2 here. Most of them are supplied by our site. Hope this information will be useful for your research of Spna2.
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References
- Chin, MS; Hooper, LC; et al. Identification of alpha-fodrin as an autoantigen in experimental coronavirus retinopathy (ECOR). JOURNAL OF NEUROIMMUNOLOGY 272:42-50(2014).
- Valiyaveettil, M; Alamneh, YA; et al. Cytoskeletal protein alpha-II spectrin degradation in the brain of repeated blast exposed mice. BRAIN RESEARCH 1549:32-41(2014).
