SSRP1
-
Official Full Name
structure specific recognition protein 1 -
Overview
SSRP1 is a nuclear protein and a component of the FACT complex (facilitates chromatin transcription). The FACT complex is composed of the SUPT16H (FACT140) and the SSRP1 FACTp80 proteins. This complex interacts with nucleosomes and histone H2A/H2B dimers -
Synonyms
SSRP1;structure specific recognition protein 1;FACT complex subunit SSRP1;facilitates chromatin remodeling 80 kDa subunit;FACT80;hSSRP1;FACTp80;cisplatin-DNA SSRP;FACT 80 kDa subunit;high mobility group box;structure-specific recognition protein
Recombinant Proteins
- Human
- Chicken
- Rhesus macaque
- Rat
- Mouse
- E.coli
- Mammalian Cells
- HEK293
- His
- Non
- DDK
- Myc
- Avi
- Fc
Involved Pathway
SSRP1 involved in several pathways and played different roles in them. We selected most pathways SSRP1 participated on our site, such as Disease,Formation of HIV elongation complex in the absence of HIV Tat,Formation of HIV-1 elongation complex containing HIV-1 Tat, which may be useful for your reference. Also, other proteins which involved in the same pathway with SSRP1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Disease | RNF43,HDAC6,TH1L,DERL2,OGN,NPM1,SUPT4H1,PSTPIP2,KREMEN2,OPN1LW |
| Formation of HIV elongation complex in the absence of HIV Tat | RDBP,SUPT5H,WHSC2,CDK9,ELL,COBRA1,PSTPIP2,CTDP1,TCEA1,TH1L |
| Formation of RNA Pol II elongation complex | CCNT2A,SUPT4H1,RDBP,SUPT16H,WHSC2,ELL,CCNT2B,GM3258,CDK9,TH1L |
| Gene Expression | BARHL1,NR2E3,HNRNPL,ZNF558,HNRNPF,PAIP1,GTF3C3,THG1L,POLR3C,ZNF184 |
| HIV Transcription Elongation | TCEB3 |
| HIV Infection | APOBEC3G,AP1G1,PSTPIP2,AP1S1,RCC1,PACS1,TCEB3,CHMP4C,NMT2,ELL |
| HIV Life Cycle | RCC1,CHMP4C,NMT2,CHMP4B,ELL,CDK9,VPS37A,PSTPIP2,TAF1L,NMT1 |
| Formation of HIV-1 elongation complex containing HIV-1 Tat | CDK9,TH1L,TCEA1,WHSC2,SUPT5H,ELL,CTDP1,SUPT4H1,RDBP,TCEB3 |
Protein Function
SSRP1 has several biochemical functions, for example, DNA binding,chromatin binding,poly(A) RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SSRP1 itself. We selected most functions SSRP1 had, and list some proteins which have the same functions with SSRP1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| DNA binding | SMARCA5,ZNF654,SETDB1B,NR5A1B,POLR2I,ZNF423,ZNF620,PAX1,PHC1,HIST1H2BI |
| chromatin binding | CBX4,GATA2A,RAG2,HMG20B,EGFR,TFAP2A,TOX4,NR5A1A,C19orf40,HDGF2 |
| protein binding | FLOT2,IL-8,GSTM5,TES,PRDM1,SPRY2,DAAM1,AGTRAP,CHRNA5,EGFR |
| poly(A) RNA binding | RPS7,PARN,SKIV2L2,CSTF3,SLC16A3,RBM5,RPL30,MRPL15,RBM14,HNRNPL |
Interacting Protein
SSRP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SSRP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of SSRP1.
MCM4;CSNK2A1;SUPT16H;VCAM1;HDGF;CD3EAP
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