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SSTR1

  • Official Full Name

    somatostatin receptor 1

  • Overview

    Somatostatin acts at many sites to inhibit the release of many hormones and other secretory proteins. The biological effects of somatostatin are probably mediated by a family of G protein-coupled receptors that are expressed in a tissue-specific manner. The encoded protein is a member of the superfamily of somatostatin receptors having seven transmembrane segments, and is expressed in highest levels in jejunum and stomach.
  • Synonyms

    SSTR1; somatostatin receptor 1; somatostatin receptor type 1; G-protein coupled receptor; SS1R; SS1-R; SRIF-2; SS-1-R;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Assay Kits
  • Canis lupus familiaris (Dog) (Canis familiaris)
  • Chicken
  • Homo sapiens (Human)
  • Human
  • Mouse
  • Mus musculus (Mouse)
  • Rat
  • Rattus norvegicus (Rat)
  • E.coli
  • E.coli expression system
  • HEK293
  • Mammalian Cell
  • GST
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human SSTR1-2970H Recombinant Human SSTR1, GST-tagged E.coli GST 1-70aa
Human SSTR1-1453HCL Recombinant Human SSTR1 293 Cell Lysate HEK293 N/A
Mouse SSTR1-16042M Recombinant Mouse SSTR1 Protein Mammalian Cell His
Mouse SSTR1-8751M Recombinant Mouse SSTR1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse SSTR1-8751M-B Recombinant Mouse SSTR1 Protein Pre-coupled Magnetic Beads HEK293
Rat SSTR1-5760R Recombinant Rat SSTR1 Protein Mammalian Cell His
Rat SSTR1-5419R Recombinant Rat SSTR1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat SSTR1-5419R-B Recombinant Rat SSTR1 Protein Pre-coupled Magnetic Beads HEK293
Canis lupus familiaris (Dog) (Canis familiaris) RFL25914CF Recombinant Full Length Dog Somatostatin Receptor Type 1(Sstr1) Protein, His-Tagged E.coli expression system His Full Length (1-391)
Homo sapiens (Human) RFL14899HF Recombinant Full Length Human Somatostatin Receptor Type 1(Sstr1) Protein, His-Tagged E.coli expression system His Full Length (1-391)
Mus musculus (Mouse) RFL3534MF Recombinant Full Length Mouse Somatostatin Receptor Type 1(Sstr1) Protein, His-Tagged E.coli expression system His Full Length (1-391)
Rattus norvegicus (Rat) RFL2406RF Recombinant Full Length Rat Somatostatin Receptor Type 1(Sstr1) Protein, His-Tagged E.coli expression system His Full Length (1-391)
Chicken SSTR1-3796C Recombinant Chicken SSTR1 Mammalian Cell His
Kit-0942 PPARγ-Competitor Assay Kit, Green N/A
Kit-1520 SSTR1 U2OS β-Arrestin GPCR Assay Kit N/A
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • SSTR1 Related Articles

SSTR1 involved in several pathways and played different roles in them. We selected most pathways SSTR1 participated on our site, such as Class A/1 (Rhodopsin-like receptors), G alpha (i) signalling events, GPCR downstream signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with SSTR1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Class A/1 (Rhodopsin-like receptors)NPB;ADRB1;SSTR1;HCAR1-2;PRLH;NMUR1;CXCR7B;GPBAR1;GPR65
G alpha (i) signalling eventsGPR18;SST;POMCB;GAL;OXGR1A.1;OPN1LW1;PYY;ANXA1B;FPR-RS4
GPCR downstream signalingRGS19;DGKB;NMUR1;ANXA1B;GCGB;DRD4;RGS1;RHOL;GCGA
GPCR ligand bindingNMS;NMBA;GPR55A;CALCA;GPR39;CALCRL;GPR77;GHRH;CNR1
GPCRs, Class A Rhodopsin-likeGPR20;RRH;OPN3;SSTR1;CCRL2;DRD4;NMUR1;CNR1;CHRM4
Neuroactive ligand-receptor interactionTAAR4;HTR1A;KISS1R;NPFFR1L2;PTGER4A;GRM8;AGTR2;TAAR15;CSH1
Peptide GPCRsSSTR4;CXCR6;SSTR5;CX3CR1;TAC4;SSTR1
Peptide ligand-binding receptorsRXFP2;EDN2;FPR-RS6;TAC1;EDN3;INSL3;CCL35.2;KISS1;NPS

SSTR1 has several biochemical functions, for example, neuropeptide binding, somatostatin receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SSTR1 itself. We selected most functions SSTR1 had, and list some proteins which have the same functions with SSTR1. You can find most of the proteins on our site.

Function Related Protein
neuropeptide bindingSSTR1;GPR149;GALR1;SSTR4;OPRD1A;ADCYAP1R1;PTGDR2;OPRD1;OPRL1
somatostatin receptor activitySSTR1;SSTR4;SSTR3;SSTR2;SSTR5

SSTR1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SSTR1 here. Most of them are supplied by our site. Hope this information will be useful for your research of SSTR1.

Elston, MS; Meyer-Rochow, GY; et al. Increased SSTR2A and SSTR3 expression in succinate dehydrogenase-deficient pheochromocytomas and paragangliomas. HUMAN PATHOLOGY 46:390-396(2015).
Lambertini, C; Barzaghi-Rinaudo, P; et al. Evaluation of somatostatin receptor subtype expression in human neuroendocrine tumors using two sets of new monoclonal antibodies. REGULATORY PEPTIDES 187:35-41(2013).
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