SSTR4

  • Official Full Name

    somatostatin receptor 4
  • Overview

    transmembrane receptor for somatostatin; coupled to a G-protein which inhibits adenylyl cyclase; may also activate the mitogen-activated protein (MAP) kinase cascade
  • Synonyms

    SSTR4;somatostatin receptor 4;somatostatin receptor type 4;SS 4R;SS4R;SST R4;SSTR 4;SS4-R;SS-4-R;Somatostatin receptor subtype 4 Rattus norvegicus Sprague-Dawley major hippocampal somatostatin receptor (SSTR4) mRNA;Smstr4

Recombinant Proteins

  • Chicken
  • Rat
  • Mus musculus
  • Human
  • Mammalian Cells
  • E.coli
  • HEK293
  • His
  • Avi
  • Fc
Cat.# Product name Source (Host) Species Tag Protein Length Price
SSTR4-3163C Recombinant Chicken SSTR4 Mammalian Cells Chicken His
SSTR4-5763R Recombinant Rat SSTR4 Protein Mammalian Cells Rat His
RFL12898MF Recombinant Full Length Mouse Somatostatin Receptor Type 4(Sstr4) Protein, His-Tagged E.coli Mus musculus His Full L. Full Length (1-384)
RFL21724HF Recombinant Full Length Human Somatostatin Receptor Type 4(Sstr4) Protein, His-Tagged E.coli Human His Full L. Full Length (1-388)
RFL24711RF Recombinant Full Length Rat Somatostatin Receptor Type 4(Sstr4) Protein, His-Tagged E.coli Rat His Full L. Full Length (1-384)
SSTR4-4520H Recombinant Human SSTR4 protein, His-tagged Mammalian Cells Human His
SSTR4-5422R Recombinant Rat SSTR4 Protein, His (Fc)-Avi-tagged HEK293 Rat Avi&Fc&His
SSTR4-5422R-B Recombinant Rat SSTR4 Protein Pre-coupled Magnetic Beads HEK293 Rat

    Involved Pathway

    SSTR4 involved in several pathways and played different roles in them. We selected most pathways SSTR4 participated on our site, such as Class A/1 (Rhodopsin-like receptors),G alpha (i) signalling events,GPCR downstream signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with SSTR4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Peptide ligand-binding receptors NMB,OXTRL,PNOC,SSTR1,NPFF,PPY,ACKR4,CCL19A.2,NPS,PROKR2
    Neuroactive ligand-receptor interaction GRID2,GRIN2BB,TAAR14A,GNRHR2,TAAR8B,PTGER1C,SSTR1,KISS1RA,S1PR4,AGTR1A
    GPCR downstream signaling PMCH,SOUL3,TAC3,RGS12,PPY,NMB,RGS18,CRHR2,PROK1,SST
    GPCR ligand binding INSL3,LTB4R,CALCB,PENK,SST,GPR55A,FPR-RS3,ADM2A,TAC3,CNR2
    Peptide GPCRs TAC4,SSTR1,CX3CR1,SSTR5,CXCR6
    Class A/1 (Rhodopsin-like receptors) DRD1,RLN3,ADRA2A,TAC2,NMUR1,AGT,CCR9,FPR-RS6,UTS2D,CCL27
    GPCRs, Class A Rhodopsin-like ADORA3,GPR12,CNR2,GPR68,FPR-RS4,GPR39,GPR18,PTGDR2,CCR1,GPR171
    G alpha (i) signalling events CCR7,GAL,OPN5,LPAR2B,CHRM4,PYY,GPR18,TAS2R7,APPA,S1PR3

    Protein Function

    SSTR4 has several biochemical functions, for example, neuropeptide binding,somatostatin receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SSTR4 itself. We selected most functions SSTR4 had, and list some proteins which have the same functions with SSTR4. You can find most of the proteins on our site.

    Function Related Protein
    neuropeptide binding GPR149,OPRM1,NPBWR1,NPY8AR,MRGPRX2,ADCYAP1R1,OPRK1,GALR1,SSTR1,MC3R
    somatostatin receptor activity SSTR3,SSTR5,SSTR1,SSTR2

    Interacting Protein

    SSTR4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SSTR4 here. Most of them are supplied by our site. Hope this information will be useful for your research of SSTR4.

    Resources

    References

    • Frati, A; Rouzier, R; et al. Expression of Somatostatin Type-2 and-4 Receptor and Correlation with Histological Type in Breast Cancer. ANTICANCER RESEARCH 34:3997-4003(2014).
    • Yamamoto, J; Ohnuma, K; et al. Regulation of somatostatin receptor 4-mediated cytostatic effects by CD26 in malignant pleural mesothelioma. BRITISH JOURNAL OF CANCER 110:2232-2245(2014).

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