STAG1

  • Official Full Name

    stromal antigen 1
  • Overview

    This gene is a member of the SCC3 family and is expressed in the nucleus. It encodes a component of cohesin, a multisubunit protein complex that provides sister chromatid cohesion along the length of a chromosome from DNA replication through prophase and prometaphase, after which it is dissociated in preparation for segregation during anaphase.
  • Synonyms

    STAG1;stromal antigen 1;cohesin subunit SA-1;SA 1;SCC3A;SCC3 homolog 1;nuclear protein stromal antigen 1;SA1;DKFZp781D1416
Cat.# Product name Source (Host) Species Tag Protein Length Price
STAG1-2986H Recombinant Human STAG1 protein, GST-tagged E.coli Human GST
STAG1-16089M Recombinant Mouse STAG1 Protein Mammalian Cells Mouse His
STAG1-29260TH Recombinant Human STAG1, His-tagged E.coli Human His 872-1258 a.a.
STAG1-1430HCL Recombinant Human STAG1 293 Cell Lysate HEK293 Human Non
STAG1-8771M Recombinant Mouse STAG1 Protein, His (Fc)-Avi-tagged HEK293 Mouse Avi&Fc&His
STAG1-8771M-B Recombinant Mouse STAG1 Protein Pre-coupled Magnetic Beads HEK293 Mouse

    Involved Pathway

    STAG1 involved in several pathways and played different roles in them. We selected most pathways STAG1 participated on our site, such as Cell Cycle,Cell Cycle, Mitotic,Cohesin Loading onto Chromatin, which may be useful for your reference. Also, other proteins which involved in the same pathway with STAG1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Establishment of Sister Chromatid Cohesion PDS5B,CDCA5,ESCO1,PDS5A,STAG2,WAPAL,ESCO2
    Meiosis MSH5,SYCP2,SYCE1,DMC1,MND1,POT1,PSMC3IP,DIDO1,TERF2IP,TEX12
    Cell Cycle, Mitotic MAPRE1B,DULLARD,USO1,E2F4,CETN2,DNA2,CDK11B,E2F3,SPDL1,LIN9
    Cohesin Loading onto Chromatin STAG2,WAPAL,NIPBLA,NIPBLB,MAU2,PDS5B,NIPBL,PDS5A
    Cell cycle SMC1AL,TGFB3,CDKN2A,AHCTF1,OFD1,CUL1A,TUBGCP5,HDAC1,FOXM1,MYC
    M Phase SMC4,SETB,NCAPD2,NCAPG,ZW10,CENPI,ARPP19,NSL1,PDS5B,PHF8
    Meiotic synapsis TERF2IP,SUN2,FKBP6,TEX12,TINF2,SYCE2,ACD,TERF1,TERF2,SYCP1

    Protein Function

    STAG1 has several biochemical functions, for example, chromatin binding,protein binding,transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding. Some of the functions are cooperated with other proteins, some of the functions could acted by STAG1 itself. We selected most functions STAG1 had, and list some proteins which have the same functions with STAG1. You can find most of the proteins on our site.

    Function Related Protein
    chromatin binding MSL1,LMO2,TCF7L1B,SIRT7,UBTF,AIRE,POLG,CENPA,KDM5A,NSBP1
    transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding IKZF3,CSRNP1,HSF2,SOHLH1,ETV5,ATF1,MAFGA,SRF,EP300,ATF2
    protein binding NME2,DNMT1,WLS,FUCA2,SGTA,S100A4,AQP5,UBA3,CENPK,EFNA1

    Interacting Protein

    STAG1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with STAG1 here. Most of them are supplied by our site. Hope this information will be useful for your research of STAG1.

    SMC3;RAD21;WAPAL

    Resources

    References

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