TAE1
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Official Full Name
TAE1 Tae1p [ Saccharomyces cerevisiae S288c ] -
Overview
Alpha-N-methyltransferase that methylates the N-terminus of target proteins containing the N-terminal motif [Ala/Pro/Ser]-Pro-Lys when the initiator Met is cleaved. Specifically catalyzes mono-, di- or tri-methylation of exposed alpha-amino group of Ala or Ser residue in the [Ala/Ser]-Pro-Lys motif and mono- or di-methylation of Pro in the Pro-Pro-Lys motif. Responsible for the N-terminal methylation of the ribosomal proteins RPL12A, RPL12B, RPS25A and RPS25B. -
Synonyms
TAE1;Tae1p;YBR261C, NTM1
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| TAE1-7904H | Recombinant Human TAE1 | E.coli | Human | Non |
|
Involved Pathway
TAE1 involved in several pathways and played different roles in them. We selected most pathways TAE1 participated on our site, such as Choline metabolism in cancer,Effects of PIP2 hydrolysis,G alpha (q) signalling events, which may be useful for your reference. Also, other proteins which involved in the same pathway with TAE1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| G alpha (q) signalling events | NMU,GPR132B,ADRA1D,MLN,PROKR2,UTS2,GCGB,ANXA1A,CYSLTR1,TAC2 |
| Hemostasis | DGKG,HBD,BA1L,ITPK1,AKAP1B,F13A1A.1,F11R.2,GATA1,IRF1B,JAM2B |
| GPCR downstream signaling | GPR68,PROKR2,CCR6,ADRB3,SCT,ARHGEF18,CCL35.2,DCLRE1B,ABR,PTH |
| Glycerophospholipid metabolism | PNPLA6,LPCAT4,PLD1A,PISD,DGKB,AGPAT9L,LYCAT,CHKA,LPIN1,PLA2G16 |
| Choline metabolism in cancer | PLA2G4A,TSC1,PDPK1,HIF1A,MAPK1,SLC22A1,DGKG,RAC1,SLC44A2,PIK3CD |
| Glycerolipid metabolism | PNLIP,ALDH2.2,AGPAT1,AGPAT2,LIPC,glpK,AKR1A1,MBOAT2,PPAP2B,PNLIPRP3 |
| Gastrin-CREB signalling pathway via PKC and MAPK | TAC3,MGLL,LPAR5A,NPFF,MLN,NTS,DGKB,NMBB,FPR-RS3,ANXA1A |
| Effects of PIP2 hydrolysis | TRPC7,DGKQ,ABHD6B,ABHD12,PRKCHB,DGKA,DGKB,TRPC3,MGLL,TRPC6A |
Protein Function
TAE1 has several biochemical functions, for example, ATP binding,diacylglycerol kinase activity,enzyme inhibitor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by TAE1 itself. We selected most functions TAE1 had, and list some proteins which have the same functions with TAE1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | PAX2,ECD,NCSTN,POP5,PML,RGS6,TGFB2,MAP3K3,SENP1,AARSD1 |
| metal ion binding | NAIP6,FCNA,TRIM7,PLA2G12B,OLA1,TRMT44,GMPR2,EXO1,DCST1,KCND3 |
| protein C-terminus binding | TNNI3K,VIM,SNTG1,SIAH1A,PDZD11,HESX1,YWHAB,SLC9A3R2,PRKAA1,PPP2CB |
| diacylglycerol kinase activity | DGKD,DGKG,DGKQ,DGKAA,DGKE,DGKZ,DGKB,DGKA,AGK |
| ATP binding | NEK4,RHOBTB3,BLK,SPHK2,CLK2,AMHR2,ADCK2,KCNJ10,PSMC3,DDX39B |
| enzyme inhibitor activity | UGT1A9,APOV1,PPP1R12A,HSPBP1,PDE6G,CALU,PRPSAP1,OAZ1A,PLN,ATPIF1B |
| lipid kinase activity | PIK3C2B,DGKZ |
Interacting Protein
TAE1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TAE1 here. Most of them are supplied by our site. Hope this information will be useful for your research of TAE1.
ILV1;CTT1;PIS1;SNA3;CTA1;HSP26;SEC18;ycp7_yeast;RNQ1;CAT2;MAC1;nnrd_yeast;PCH2;PBP2;yhr2_yeast;phs_yeast;QNS1;UBA4;APE4;MBB1
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