TAF10

  • Official Full Name

    Taf10p

  • Overview

    The basal transcription factor TFIID plays a central role in the regulation of gene expression in Eukaryota and is a large protein complex composed of TATA box-binding protein (TBP) and 14 kinds of TBP-associated factors (TAF). TFIID directly recognizes and binds to different kinds of core promoter elements that localize near the transcription initiation site and forms a scaffold for the other basal transcription factors to assemble. At the same time, it transmits transcriptional activation signal originating from transcription regulating factors to RNA polymerase II. Taf10p is one of the subunits of TFIID and in the case of budding yeast, it is composed of 206 amino acid residues (aa). Taf10p is also a subunit of histoneacetylase complex SAGA which is said to have an overlapping function with TFIID. This protein contains histone folds in its interior and forms dimers with Taf3p and Taf8p each.
  • Synonyms

    TAF10; Taf10p; TAF23; TAF25; NP_010451.1; YDR167W; Eukaryota; Fungi; Ascomycota; Saccharomycotina (true yeasts); Taphrinomycotina; Schizosaccharomycetes (fission yeasts); Basidiomycota; Agaricomycotina; Tremellomycetes; Pucciniomycotina; Microbotryomycetes;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • Mammalian Cell
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • Myc|DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human TAF10-3099H Recombinant Human TAF10, His-tagged E.coli His 70-218aa
Human TAF10-2346H Recombinant Human TAF10 protein, His-tagged E.coli His
Human TAF10-2139HCL Recombinant Human TAF10 cell lysate N/A
Human TAF10-131H Recombinant Human TAF10 Protein, MYC/DDK-tagged HEK293 Myc/DDK
Mouse TAF10-16385M Recombinant Mouse TAF10 Protein Mammalian Cell His
Mouse TAF10-8963M Recombinant Mouse TAF10 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Taf10-6274M Recombinant Mouse Taf10 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse TAF10-8963M-B Recombinant Mouse TAF10 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque TAF10-4605R Recombinant Rhesus monkey TAF10 Protein, His-tagged Mammalian Cell His
Rhesus Macaque TAF10-4421R Recombinant Rhesus Macaque TAF10 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque TAF10-4421R-B Recombinant Rhesus Macaque TAF10 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish TAF10-3947Z Recombinant Zebrafish TAF10 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

TAF10 involved in several pathways and played different roles in them. We selected most pathways TAF10 participated on our site, such as Basal transcription factors, Herpes simplex infection, which may be useful for your reference. Also, other proteins which involved in the same pathway with TAF10 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Basal transcription factorsGTF2H5;MNAT1;GTF2IRD1;TAF8;GTF2F2B;TAF5L;GTF2I;TAF13;TAF10
Herpes simplex infectionPPP1CBL;THOC4;SRSF1;HLA-DQA2;MHC2DEB;CUL1B;Hc;CCL5;TLR2-1

TAF10 has several biochemical functions, for example, RNA polymerase binding, enzyme binding, estrogen receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TAF10 itself. We selected most functions TAF10 had, and list some proteins which have the same functions with TAF10. You can find most of the proteins on our site.

Function Related Protein
RNA polymerase bindingRRN3;BIN1;GSG1;STOM;PKN2;WDHD1;ANP32B;TAF10;YTHDC2
enzyme bindingSlc4a2;RPA3;RCOR1;TGFB1;TSPAN14;HINFP;TSPAN15;PDE4DIP;GOLPH3
estrogen receptor bindingPPARGC1B;NSD1;HSD17B10;ISL1;CNOT1;PPARG;ARRB1;PPID;DDX17
contributes_to histone acetyltransferase activityTEX30;SUPT3H;SAP130;TAF9;ING3;SUPT7L;ELP4;KAT5;TADA1
protein bindingPKD2;NDUFS2;TCHP;SRPK3;ERAP1;WASH1;HBZ;FBXO25;PPP2R5A
contributes_to protein bindingMSH2;CRY1A;INTS10;PAK1;MSH6;TGFBR3;INHA;ACVR2A;CPSF3L
transcription coactivator activityCARM1;CREBBP;RNF20;BRCA1;FUS;NFYC;RUNX1;PMF1;ACTL6B
contributes_to transcription factor activity, sequence-specific DNA bindingSOX19B;NKX2;NKX2-5;VDRB;HNRNPAB;TAF7;GATA4;VDR;MAFGB

TAF10 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TAF10 here. Most of them are supplied by our site. Hope this information will be useful for your research of TAF10.

TBP; ATXN7; SETD7; KAT2B; BRCA1; FTL; h3_peptide_2-18; TAF4; MED26

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