TAF11
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Official Full Name
TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 28kDa -
Overview
The basal transcription factor TFIID plays a central role in the regulation of gene expression in Eukaryota and is a large protein complex composed of TATA box-binding protein (TBP) and 14 kinds of TBP-associated factors (TAF). TFIID directly recognizes and binds to different kinds of core promoter elements that localize near the transcription initiation site and forms a scaffold for the other basal transcription factors to assemble. At the same time, it transmits transcriptional activation signal originating from transcription regulating factors to RNA polymerase II. Taf11p is one of the subunits of TFIID and in the case of budding yeast, it is composed of 346 amino acid residues (aa). -
Synonyms
TAF11;TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 28kDa;TAF2I, TATA box binding protein (TBP) associated factor, RNA polymerase II, I, 28kD;transcription initiation factor TFIID subunit 11;TAFII28;TAFII-28;TAF(II)28
Recombinant Proteins
- Human
- Chicken
- Rhesus macaque
- Rat
- Zebrafish
- Mouse
- E.coli
- Mammalian Cells
- HEK293
- GST
- His
- Non
- DDK
- Myc
- Avi
- Fc
Involved Pathway
TAF11 involved in several pathways and played different roles in them. We selected most pathways TAF11 participated on our site, such as Basal transcription factors, which may be useful for your reference. Also, other proteins which involved in the same pathway with TAF11 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Basal transcription factors | TAF9,GTF2E2,GTF2H1,GTF2H3-2,GTF2IRD1,GTF2H3,CDK7,GTF2H2C,MNAT1,GTF2H2 |
Protein Function
TAF11 has several biochemical functions, for example, DNA binding,protein N-terminus binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TAF11 itself. We selected most functions TAF11 had, and list some proteins which have the same functions with TAF11. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein heterodimerization activity | DMRT3,NR2C2,DR1,ADRA1B,RRAGA,ADD2,TGFB1,SCGB2A1,ALX1,MAFG |
| protein N-terminus binding | MORF4L1,SMARCC1,KCNIP1,GTF2H3,EXOC5,ALG2,SNCA,NCOR2,NPAT,STX1A |
| vitamin D receptor binding | SNW1,MED16,MED4,MED1,RXRA,MED24,RUNX2B,MED14,MED17,MED30 |
| thyroid hormone receptor binding | GAS2L1,PRMT2,MED30,MED13,NR0B2,TRIP6,ZNHIT3,TRIP12,MED24,GTF2B |
| protein binding | RBM17,COL10A1,NSMAF,S100A16,TMPRSS7,KLF2,BRD4,MAK,AP5S1,WWOX |
| transcription coactivator activity | MLL5,RBPMS,SMARCD1,MYCBP,MYOD1,DYRK1B,KAT2A,PRMT2,TCERG1,HSF2 |
| DNA binding | PSMC3IP,TFIP11,SCML2,ZHX2,PHC1,VDRB,PBX1,ZNF576.2,EVE1,POGK |
Interacting Protein
TAF11 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TAF11 here. Most of them are supplied by our site. Hope this information will be useful for your research of TAF11.
APPBP2;TAF13;q5nh75_fratt;h3_peptide_2-18;Mtx1;MED26;MYH7;TBP;CCNA2;RAB4B;KPNB1;Prkaa1;Slain1;Ufl1;TSNAX;Ndc80;Cul3
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