TAF1B Protein

TAF1B

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TAF1B

Official Full Name TATA box binding protein (TBP)-associated factor, RNA polymerase I, B, 63kDa
Background Initiation of transcription by RNA polymerase I requires the formation of a complex composed of the TATA-binding protein (TBP) and three TBP-associated factors (TAFs) specific for RNA polymerase I. This complex, known as SL1, binds to the core promoter of ribosomal RNA genes to position the polymerase properly and acts as a channel for regulatory signals. This gene encodes one of the SL1-specific TAFs.
Synonyms TAF1B; TATA box binding protein (TBP)-associated factor, RNA polymerase I, B, 63kDa; TATA box binding protein (TBP) associated factor, RNA polymerase I, B, 63kD; TATA box-binding protein-associated factor RNA polymerase I subunit B; RAF1B; RAFI63; SL1; TAFI63; TAF1B TATA box binding protein (TBP) associated factor, RNA polymerase I, B, 63kDa; TATA box binding protein associated factor 1B; TAB1 B; TATA box binding protein associated factor RNA polymerase I subunit B; SL1, 63kD subunit; OTTHUMP00000200348; TBP-associated factor 1B; TATA box-binding protein-associated factor 1B; transcription initiation factor SL1/TIF-IB subunit B; RNA polymerase I-specifi; MGC:9349
    • Species :
    • Chicken
    • Cynomolgus Monkey
    • Human
    • Mouse
    • Rat
    • Zebrafish
    • Source :
    • HEK293
    • Mammalian Cell
    • Tag :
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human TAF1B-1271HCL Recombinant Human TAF1B 293 Cell Lysate HEK293 N/A
    Mouse TAF1B-16391M Recombinant Mouse TAF1B Protein Mammalian Cell His
    Rat TAF1B-5914R Recombinant Rat TAF1B Protein Mammalian Cell His
    Cynomolgus Monkey TAF1B-998C Recombinant Cynomolgus TAF1B Protein, His-tagged Mammalian Cell His
    Chicken TAF1B-1558C Recombinant Chicken TAF1B Mammalian Cell His
    Zebrafish TAF1B-3092Z Recombinant Zebrafish TAF1B Mammalian Cell His

    TAF1B involved in several pathways and played different roles in them. We selected most pathways TAF1B participated on our site, such as Epigenetic regulation of gene expression, Gene Expression, Negative epigenetic regulation of rRNA expression, which may be useful for your reference. Also, other proteins which involved in the same pathway with TAF1B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Epigenetic regulation of gene expression SMARCA5; SUDS3; SAP130; DNMT3B; UHRF1; DNMT3L; RRP8; TET2; TAF1C; SAP30
    Gene Expression ZNF565; ZNF547; POP4; FARS2; EARS2; PTRF; CPSF4; TNKS1BP1; ZNF100; ZNF202
    Negative epigenetic regulation of rRNA expression SAP30; SAP130; TAF1C; TAF1A; TAF1D; TAF1B; SIN3B; SUDS3; BAZ2A; DNMT3B
    NoRC negatively regulates rRNA expression DNMT3B; TAF1B; EFCAB11; DNMT1; SUDS3; TAF1C; TAF1A; SIN3B; SAP30L; SAP130
    RNA Polymerase I Chain Elongation TAF1B; CBX3A; CBX3; CD3EAP; EFCAB11; TAF1A; TAF1C; TAF1D; UBTF
    RNA Polymerase I Promoter Clearance TAF1D; GATAD2AB; MBD3A; MTA2; MTA1; TAF1B; MBD3B; EFCAB11; UBTF; TAF1C
    RNA Polymerase I Promoter Escape TAF1C; TAF1B; CD3EAP; TAF1D; RRN3; UBTF; EFCAB11; TAF1A
    RNA Polymerase I Transcription PTRF; CD3EAP; MBD3A; CBX3A; GATAD2AB; CHD4; GATAD2B; TAF1C; MTA1; RRN3

    TAF1B has several biochemical functions, for example, RNA polymerase I CORE element sequence-specific DNA binding, TBP-class protein binding, metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TAF1B itself. We selected most functions TAF1B had, and list some proteins which have the same functions with TAF1B. You can find most of the proteins on our site.

    Function Related Protein
    RNA polymerase I CORE element sequence-specific DNA binding SMARCB1; TAF1C; RRN3; PIH1D1; SMARCA4; TAF1B; EFCAB11; BAZ2A
    TBP-class protein binding GTF2A2; GTF2A1; PSMC4; EFCAB11; BRF1; PSMC1; PSMC2; TAF1; PSMC1B; TAF1L
    metal ion binding PPP6C; ZNF219; GNAL; CYP2AA1; LFNG; ARAF; DICER1; ZBTB39; GM757; PDE4D
    protein binding CRB1; TICAM1; NUP50; KCNRG; PKP1; MAP2K3; PAEP; WDR24; ATF6B; ARPM1
    transcription factor activity, RNA polymerase I CORE element binding transcription factor recruiting EFCAB11; TAF1B
    transcription factor activity, sequence-specific DNA binding SNAPC4; KLF2; ESR2; MZF1; ZFP322A; FOXL2; TEAD3B; ZNF606; SMAD2; ATF7B

    TAF1B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TAF1B here. Most of them are supplied by our site. Hope this information will be useful for your research of TAF1B.

    TBP; SET; SRPK1; TAF1C; TAF1A; TAF1D; NAPB; h3_peptide_2-18; POLR1A

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