TAF1B

  • Official Full Name

    TATA box binding protein (TBP)-associated factor, RNA polymerase I, B, 63kDa

  • Overview

    Initiation of transcription by RNA polymerase I requires the formation of a complex composed of the TATA-binding protein (TBP) and three TBP-associated factors (TAFs) specific for RNA polymerase I. This complex, known as SL1, binds to the core promoter of ribosomal RNA genes to position the polymerase properly and acts as a channel for regulatory signals. This gene encodes one of the SL1-specific TAFs.
  • Synonyms

    TAF1B; TATA box binding protein (TBP)-associated factor, RNA polymerase I, B, 63kDa; TATA box binding protein (TBP) associated factor, RNA polymerase I, B, 63kD; TATA box-binding protein-associated factor RNA polymerase I subunit B; RAF1B; RAFI63; SL1; TAFI63; TAF1B TATA box binding protein (TBP) associated factor, RNA polymerase I, B, 63kDa; TATA box binding protein associated factor 1B; TAB1 B; TATA box binding protein associated factor RNA polymerase I subunit B; SL1, 63kD subunit; OTTHUMP00000200348; TBP-associated factor 1B; TATA box-binding protein-associated factor 1B; transcription initiation factor SL1/TIF-IB subunit B; RNA polymerase I-specifi; MGC:9349;

  • Cell & Tissue Lysates
  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Cynomolgus Monkey
  • Human
  • Mouse
  • Rat
  • Zebrafish
  • HEK293
  • Mammalian Cell
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human TAF1B-1271HCL Recombinant Human TAF1B 293 Cell Lysate HEK293 N/A
Mouse TAF1B-16391M Recombinant Mouse TAF1B Protein Mammalian Cell His
Mouse TAF1B-8965M Recombinant Mouse TAF1B Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse TAF1B-8965M-B Recombinant Mouse TAF1B Protein Pre-coupled Magnetic Beads HEK293
Rat TAF1B-5914R Recombinant Rat TAF1B Protein Mammalian Cell His
Rat TAF1B-5573R Recombinant Rat TAF1B Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat TAF1B-5573R-B Recombinant Rat TAF1B Protein Pre-coupled Magnetic Beads HEK293
Cynomolgus Monkey TAF1B-998C Recombinant Cynomolgus TAF1B Protein, His-tagged Mammalian Cell His
Cynomolgus Monkey TAF1B-741C-B Recombinant Cynomolgus Monkey TAF1B Protein Pre-coupled Magnetic Beads HEK293
Cynomolgus Monkey TAF1B-741C Recombinant Cynomolgus Monkey TAF1B Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Zebrafish TAF1B-3092Z Recombinant Zebrafish TAF1B Mammalian Cell His
Chicken TAF1B-1558C Recombinant Chicken TAF1B Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

TAF1B involved in several pathways and played different roles in them. We selected most pathways TAF1B participated on our site, such as Epigenetic regulation of gene expression, Gene Expression, Negative epigenetic regulation of rRNA expression, which may be useful for your reference. Also, other proteins which involved in the same pathway with TAF1B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Epigenetic regulation of gene expressionTAF1C;SAP18;EFCAB11;SAP30BP;SMARCA5;SUZ12A;TAF1B;SAP30;RBB4L
Gene ExpressionEFCAB11;CCDC76;ZNF471;VDRB;CD2BP2;POU2F1B;EIF1AXA;SETB;DCP1B
Negative epigenetic regulation of rRNA expressionSAP30L;TAF1C;SAP18;SIN3B;SAP130;EFCAB11;RRP8;DNMT1;SAP30
NoRC negatively regulates rRNA expressionTAF1A;SAP30L;DNMT3B;TAF1C;SAP130;BAZ2A;DNMT1;TAF1B;CD3EAP
RNA Polymerase I Chain ElongationTAF1C;CBX3;CBX3A;TAF1B;TAF1A;EFCAB11;UBTF;CD3EAP;TAF1D
RNA Polymerase I Promoter ClearanceMTA1;TAF1C;TAF1A;MBD3B;RRN3;UBTF;EFCAB11;MTA3;GATAD2AB
RNA Polymerase I Promoter EscapeUBTF;TAF1D;TAF1C;EFCAB11;TAF1B;RRN3;TAF1A;CD3EAP
RNA Polymerase I TranscriptionGATAD2A;CBX3A;CD3EAP;CBX3;RRN3;PTRFB;MTA2;TAF1A;MBD3

TAF1B has several biochemical functions, for example, RNA polymerase I CORE element sequence-specific DNA binding, TBP-class protein binding, metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TAF1B itself. We selected most functions TAF1B had, and list some proteins which have the same functions with TAF1B. You can find most of the proteins on our site.

Function Related Protein
RNA polymerase I CORE element sequence-specific DNA bindingSMARCB1;SMARCA4;BAZ2A;TAF1B;EFCAB11;TAF1C;RRN3;PIH1D1
TBP-class protein bindingPSMC3;HHEX;DR1;CAND1;TAF1;TAF1L;BRF1A;PSMC1;EFCAB11
metal ion bindingCYP8B2;SEMG1;NME6;PAK3;RORCA;B3GAT1;INSM1A;ZBTB17;CLEC7A
protein bindingOCRL;RYK;CXCR2;ARPM1;ZC3H11A;DCAF11;OLIG1;MBD3;FABP3
transcription factor activity, RNA polymerase I CORE element binding transcription factor recruitingTAF1B;EFCAB11
transcription factor activity, sequence-specific DNA bindingTAF5L;USF2;EOMESB;MSRB2;MYCA;ZNF41;LCOR;HOXB3A;IRF1B

TAF1B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TAF1B here. Most of them are supplied by our site. Hope this information will be useful for your research of TAF1B.

TBP; SET; SRPK1; TAF1C; TAF1A; TAF1D; NAPB; h3_peptide_2-18; POLR1A

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