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TAF1L

Official Full Name

TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 210kDa-like
Overview

This locus is intronless, and apparently arose in the primate lineage from retrotransposition of the transcript from the multi-exon TAF1 locus on the X chromosome. The gene is expressed in male germ cells, and the product has been shown to function interchangeably with the TAF1 product.
Synonyms

TAF1L; TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 210kDa-like; TAF1 like RNA polymerase II, TATA box binding protein (TBP) associated factor, 210kDa; transcription initiation factor TFIID subunit 1-like; TAF(II)210; TBP-asso;

Type

Recombinant Proteins
Assay Kits

Species

Human

Source

E.coli

Tag

GST
His|Flag
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	TAF1L-221H	Recombinant Human TAF1L Protein, GST-tagged	E.coli	GST	1392-1654	Inquiry
Human	TAF1L-80H	Recombinant Human TAF1L, His&FLAG-tagged	E.coli	His/Flag		Inquiry
Human	TAF1L-81H	Recombinant Human TAF1L, His&FLAG-tagged	E.coli	His/Flag		Inquiry
Human	TAF1L-217H	Recombinant Human TAF1L Protein, GST-tagged	E.coli	GST	1392-1519	Inquiry
Human	TAF1L-219H	Recombinant Human TAF1L Protein, GST-tagged	E.coli	GST	1502-1635	Inquiry
	Kit-1874	TAF1L (BD1/BD2) Inhibitor Screening Assay Kit		N/A		Inquiry
	Kit-1875	TAF1L (BD1+BD2) TR-FRET Assay Kit		N/A		Inquiry
	Kit-1876	TAF1L (BD2) Inhibitor Screening Assay Kit		N/A		Inquiry

Involved Pathway
Protein Function
Interacting Protein

TAF1L involved in several pathways and played different roles in them. We selected most pathways TAF1L participated on our site, such as Basal transcription factors, Disease, Gene Expression, which may be useful for your reference. Also, other proteins which involved in the same pathway with TAF1L were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Basal transcription factors	TAF7;GTF2H5;GTF2H2C_2;TAF11;TAF3;TAF13;GTF2F2A;TAF6L;GTF2F2
Disease	FDXR;LRRFIP1;PSIP1;APOBEC3G;KREMEN1;PPIAL4A;OS9;GCKR;WHSC2
Gene Expression	NFIX;IGF2BP3;MED13A;ZFP36L1A;PRDM7;SUZ12;ZNF563;NR2C2;ZFP37
HIV Infection	RCC1;PSIP1;ELL;TAF1L;CDK9;PDCD6IP;PACS1;VPS37A;AP1B1
HIV Life Cycle	CHMP4C;PSTPIP2;RCC1;CHMP4B;VPS37A;TCEB3;NMT2;PDCD6IP;PSIP1
HIV Transcription Initiation
Infectious disease	APOBEC3G;LTF;ANTXR2;DOCK2;TAF1L;IPO5;AP1G1;VPS37A;NMT1
Late Phase of HIV Life Cycle	NMT2;TAF1L;PDCD6IP;RCC1

TAF1L has several biochemical functions, for example, DNA binding, TBP-class protein binding, histone acetyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by TAF1L itself. We selected most functions TAF1L had, and list some proteins which have the same functions with TAF1L. You can find most of the proteins on our site.

Function	Related Protein
DNA binding	ZBTB20;RCAN1;CLSPN;ZNF781;DBX1A;HIST3H2A;HOXB13A;ZFAT;EME1
TBP-class protein binding	HHEX;PSMC3;PSMC1A;EFCAB11;PSMC4;TAF1;PSMC6;BRF1B;DR1
histone acetyltransferase activity	MED24;KAT7B;NCOA3;GTF3C4;NCOA2;vnc;METTL8;MGEA5;CSRP2BP
lysine-acetylated histone binding	BRD9;BRD3;PHIP;PSME4B;BRD7;CARM1;TAF1L;MLL1;BAZ2A
protein serine/threonine kinase activity	PLK3;ULK3;MAP2K2;MAP4K5;SGK3;ACVR1;CDC42BPG;STK17B;MARK3

TAF1L has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TAF1L here. Most of them are supplied by our site. Hope this information will be useful for your research of TAF1L.

Dlg4; PSTPIP1; TBP