TAF6

  • Official Full Name

    Taf6p

  • Overview

    The basal transcription factor TFIID plays a central role in the regulation of gene expression in Eukaryota and is a large protein complex composed of TATA box-binding protein (TBP) and 14 kinds of TBP-associated factors (TAF). TFIID directly recognizes and binds to different kinds of core promoter elements that localize near the transcription initiation site and forms a scaffold for the other basal transcription factors to assemble. At the same time, it transmits transcriptional activation signal originating from transcription regulating factors to RNA polymerase II. Taf6p is one of the subunits of TFIID and in the case of budding yeast, it is composed of 516 amino acid residues (aa). Taf6p is also a subunit of histoneacetylase complex SAGA which is said to have an overlapping function with TFIID. The protein contains histone folds in its interior and forms TAF octamer together with Taf4p, Taf9p and Taf12p.
  • Synonyms

    TAF6; Taf6p; TAF60; NP_011403.1; YGL112C; Eukaryota; Fungi; Ascomycota; Saccharomycotina (true yeasts); Taphrinomycotina; Schizosaccharomycetes (fission yeasts); Basidiomycota; Agaricomycotina; Tremellomycetes; Pucciniomycotina; Microbotryomycetes;
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human TAF6-1267HCL Recombinant Human TAF6 293 Cell Lysate HEK293 N/A
Mouse TAF6-16399M Recombinant Mouse TAF6 Protein Mammalian Cell His
Mouse TAF6-8970M Recombinant Mouse TAF6 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse TAF6-8970M-B Recombinant Mouse TAF6 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish TAF6-1280Z Recombinant Zebrafish TAF6 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

TAF6 involved in several pathways and played different roles in them. We selected most pathways TAF6 participated on our site, such as Basal transcription factors, Herpes simplex infection, which may be useful for your reference. Also, other proteins which involved in the same pathway with TAF6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Basal transcription factorsTAF5L;TAF4B;TAF1L;GTF2A1L;TAF13;TAF2;MNAT1;TBP;TAF9B
Herpes simplex infectionOAS3;C1QBP;IFNA21;Ifna11;IFNA4;CUL1;PPP1CB;HLA-DPA1;MAPK10

TAF6 has several biochemical functions, for example, DNA binding, protein binding, protein heterodimerization activity. Some of the functions are cooperated with other proteins, some of the functions could acted by TAF6 itself. We selected most functions TAF6 had, and list some proteins which have the same functions with TAF6. You can find most of the proteins on our site.

Function Related Protein
DNA bindingZBTB26;HIST1H2A9;ERCC3;FOXE1;ZNF423;NR6A1A;TIGD6;MEF2CA;EME1
protein bindingSEC24D;BCL2;MAPRE1;TBCB;F11R;COPE;GMPPB;EHD1;PHYH
protein heterodimerization activitySMAD4;HIST1H2BL;UGT1A6B;UGT1A7;ADORA1;BIK;H2AFZ;DRD1;SMC2
transcription factor activity, sequence-specific DNA bindingZNF202;NR1D4A;RORC;HOMEZ;MAFG;NFIL3-4;CTNNB1;GRHL2A;MYCN
contributes_to transcription factor activity, sequence-specific DNA bindingMAFGB;NKX2-5;FOXH1;GATA4;TAF10;TAF12;SOX1A;VDRB;VDR

TAF6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TAF6 here. Most of them are supplied by our site. Hope this information will be useful for your research of TAF6.

TBP; E2; E2; pyrF; q8ckw7_yerpe; q8czv1_yerpe; h3_peptide_2-18; MED26; CCNA2; MAPK3; WDR5; H3F3A

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